Tobias Sing
Tobias Sing
Novartis Institutes for BioMedical Research
Geverifieerd e-mailadres voor novartis.com
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ROCR: visualizing classifier performance in R
T Sing, O Sander, N Beerenwinkel, T Lengauer
Bioinformatics 21 (20), 3940-3941, 2005
26402005
The selective sphingosine 1-phosphate receptor modulator BAF312 redirects lymphocyte distribution and has species-specific effects on heart rate
P Gergely, B Nuesslein-Hildesheim, D Guerini, V Brinkmann, M Traebert, ...
Br J Pharmacol 167 (5), 1035-47, 2012
2212012
Predicting HIV coreceptor usage on the basis of genetic and clinical covariates
T Sing, AJ Low, N Beerenwinkel, O Sander, PK Cheung, FS Domingues, ...
Antiviral therapy 12 (7), 1097, 2007
2012007
Predicting HIV coreceptor usage on the basis of genetic and clinical covariates
T Sing, AJ Low, N Beerenwinkel, O Sander, PK Cheung, FS Domingues, ...
Antiviral therapy 12 (7), 1097, 2007
2012007
Visualizing the performance of scoring classifiers
T Sing, O Sander, N Beerenwinkel, T Lengauer, T Sing, O Sander
Package ROCR Version 10, 4, 2009
198*2009
ROCR: Visualizing the performance of scoring classifiers. R package version 1.0-4
T Sing, O Sander, N Beerenwinkel, T Lengauer
185*2007
Current V3 genotyping algorithms are inadequate for predicting X4 co-receptor usage in clinical isolates
AJ Low, W Dong, D Chan, T Sing, R Swanstrom, M Jensen, S Pillai, ...
Aids 21 (14), F17-F24, 2007
1712007
Computational methods for the design of effective therapies against drug resistant HIV strains
N Beerenwinkel, T Sing, T Lengauer, J Rahnenführer, K Roomp, ...
Bioinformatics 21 (21), 3943-3950, 2005
1262005
Determining human immunodeficiency virus coreceptor use in a clinical setting: degree of correlation between two phenotypic assays and a bioinformatic model
K Skrabal, AJ Low, W Dong, T Sing, PK Cheung, F Mammano, ...
Journal of clinical microbiology 45 (2), 279-284, 2007
1242007
Structural descriptors of gp120 V3 loop for the prediction of HIV-1 coreceptor usage
O Sander, T Sing, I Sommer, AJ Low, PK Cheung, PR Harrigan, ...
PLoS Comput Biol 3 (3), e58, 2007
1182007
Bioinformatics-assisted anti-HIV therapy
T Lengauer, T Sing
Nature Reviews Microbiology 4 (10), 790-797, 2006
1142006
Estimating HIV evolutionary pathways and the genetic barrier to drug resistance
N Beerenwinkel, M Däumer, T Sing, J Rahnenführer, T Lengauer, ...
The Journal of infectious diseases 191 (11), 1953-1960, 2005
1082005
Gene expression profiles differentiating between breast cancers clinically responsive or resistant to letrozole
WR Miller, A Larionov, L Renshaw, TJ Anderson, JR Walker, A Krause, ...
J Clin Oncol 27 (9), 1382-1387, 2009
1042009
Involvement of novel human immunodeficiency virus type 1 reverse transcriptase mutations in the regulation of resistance to nucleoside inhibitors
V Svicher, T Sing, MM Santoro, F Forbici, F Rodríguez-Barrios, A Bertoli, ...
Journal of virology 80 (14), 7186-7198, 2006
952006
HIV-1 gp120 V3 loop for structure-based drug design
S Sirois, T Sing, KC Chou
Current Protein and Peptide Science 6 (5), 413-422, 2005
932005
Compensatory mutations at the HIV cleavage sites p7/p1 and p1/p6-gag in therapy-naive and therapy-experienced patients
J Verheyen, E Litau, T Sing, M Daumer, M Balduin, M Oette, ...
Antiviral therapy 11 (7), 879, 2006
842006
Characterization and structural analysis of novel mutations in human immunodeficiency virus type 1 reverse transcriptase involved in the regulation of resistance to …
F Ceccherini-Silberstein, V Svicher, T Sing, A Artese, MM Santoro, ...
Journal of virology 81 (20), 11507-11519, 2007
762007
Improved prediction of response to antiretroviral combination therapy using the genetic barrier to drug resistance
A Altmann, N Beerenwinkel, T Sing, I Savenkov, M Däumer, R Kaiser, ...
Antiviral therapy 12 (2), 169, 2007
712007
Learning mixtures of localized rules by maximizing the area under the ROC curve.
T Sing, N Beerenwinkel, T Lengauer
ROCAI 4, 96-98, 2004
512004
Stable coreceptor usage of HIV in patients with ongoing treatment failure on HAART
C Lehmann, M Däumer, I Boussaad, T Sing, N Beerenwinkel, T Lengauer, ...
Journal of clinical virology 37 (4), 300-304, 2006
382006
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