| Mechanism by which 2, 2, 2-trifluoroethanol/water mixtures stabilize secondary-structure formation in peptides: a molecular dynamics study D Roccatano, G Colombo, M Fioroni, AE Mark Proceedings of the National Academy of Sciences 99 (19), 12179-12184, 2002 | 551 | 2002 |
| Rational design of shepherdin, a novel anticancer agent J Plescia, W Salz, F Xia, M Pennati, N Zaffaroni, MG Daidone, M Meli, ... Cancer cell 7 (5), 457-468, 2005 | 393 | 2005 |
| Structure-activity relationships of linear and cyclic peptides containing the NGR tumor-homing motif G Colombo, F Curnis, GMS De Mori, A Gasparri, C Longoni, A Sacchi, ... Journal of Biological Chemistry 277 (49), 47891-47897, 2002 | 241 | 2002 |
| Combinatorial drug design targeting multiple cancer signaling networks controlled by mitochondrial Hsp90 BH Kang, J Plescia, HY Song, M Meli, G Colombo, K Beebe, B Scroggins, ... The Journal of clinical investigation 119 (3), 454-464, 2009 | 229 | 2009 |
| Swe1Wee1-dependent tyrosine phosphorylation of Hsp90 regulates distinct facets of chaperone function M Mollapour, S Tsutsumi, AC Donnelly, K Beebe, MJ Tokita, MJ Lee, ... Molecular cell 37 (3), 333-343, 2010 | 178 | 2010 |
| Peptide self-assembly at the nanoscale: a challenging target for computational and experimental biotechnology G Colombo, P Soto, E Gazit TRENDS in Biotechnology 25 (5), 211-218, 2007 | 166 | 2007 |
| Modeling signal propagation mechanisms and ligand-based conformational dynamics of the Hsp90 molecular chaperone full-length dimer G Morra, G Verkhivker, G Colombo PLoS computational biology 5 (3), e1000323, 2009 | 155 | 2009 |
| Solvent dynamics and mechanism of proton transfer in human carbonic anhydrase II S Toba, G Colombo, KM Merz Journal of the American Chemical Society 121 (10), 2290-2302, 1999 | 127 | 1999 |
| β‐Hairpin conformation of fibrillogenic peptides: Structure and α‐β transition mechanism revealed by molecular dynamics simulations I Daidone, F Simona, D Roccatano, RA Broglia, G Tiana, G Colombo, ... Proteins: Structure, Function, and Bioinformatics 57 (1), 198-204, 2004 | 112 | 2004 |
| Antileukemic activity of shepherdin and molecular diversity of hsp90 inhibitors B Gyurkocza, J Plescia, CM Raskett, DS Garlick, PA Lowry, BZ Carter, ... Journal of the National Cancer Institute 98 (15), 1068-1077, 2006 | 111 | 2006 |
| Enantioselective Mukaiyama-Michael reactions of 2-carbomethoxy cyclopentenone catalyzed by chiral bis (oxazoline)-Cu (II) complexes A Bernardi, G Colombo, C Scolastico Tetrahedron letters 37 (49), 8921-8924, 1996 | 105 | 1996 |
| Small-molecule targeting of heat shock protein 90 chaperone function: rational identification of a new anticancer lead M Meli, M Pennati, M Curto, MG Daidone, J Plescia, S Toba, DC Altieri, ... Journal of medicinal chemistry 49 (26), 7721-7730, 2006 | 104 | 2006 |
| Pharmacological enhancement of α-glucosidase by the allosteric chaperone N-acetylcysteine C Porto, MC Ferrara, M Meli, E Acampora, V Avolio, M Rosa, ... Molecular Therapy 20 (12), 2201-2211, 2012 | 99 | 2012 |
| The Chaperone TRAP1 As a Modulator of the Mitochondrial Adaptations in Cancer Cells I Masgras, C Sanchez-Martin, G Colombo, A Rasola Frontiers in Oncology 7, 58, 2017 | 94 | 2017 |
| Corresponding functional dynamics across the Hsp90 Chaperone family: insights from a multiscale analysis of MD simulations G Morra, R Potestio, C Micheletti, G Colombo PLoS computational biology 8 (3), e1002433, 2012 | 94 | 2012 |
| Effect of hexafluoroisopropanol alcohol on the structure of melittin: A molecular dynamics simulation study D Roccatano, M Fioroni, M Zacharias, G Colombo Protein Science 14 (10), 2582-2589, 2005 | 94 | 2005 |
| Sequence dependence of amyloid fibril formation: insights from molecular dynamics simulations ML de la Paz, GMS de Mori, L Serrano, G Colombo Journal of molecular biology 349 (3), 583-596, 2005 | 93 | 2005 |
| Simulation of MscL gating in a bilayer under stress G Colombo, SJ Marrink, AE Mark Biophysical journal 84 (4), 2331-2337, 2003 | 93 | 2003 |
| Long-pentraxin 3 derivative as a small-molecule FGF trap for cancer therapy R Ronca, A Giacomini, E Di Salle, D Coltrini, K Pagano, L Ragona, ... Cancer cell 28 (2), 225-239, 2015 | 92 | 2015 |
| Understanding the determinants of stability and folding of small globular proteins from their energetics G Tiana, F Simona, GMS De Mori, RA Broglia, G Colombo Protein Science 13 (1), 113-124, 2004 | 91 | 2004 |
Meli MassimilianoIstituto di Scienze e Tecnologie Chimiche (SCITEC-CNR)Verified email at scitec.cnr.it
