| Potent noncovalent inhibitors of the main protease of SARS-CoV-2 from molecular sculpting of the drug perampanel guided by free energy perturbation calculations CH Zhang, EA Stone, M Deshmukh, JA Ippolito, MM Ghahremanpour, ... ACS central science 7 (3), 467-475, 2021 | 216 | 2021 |
| The Peroxidase and Cyclooxygenase Activity of Prostaglandin H Synthase SN Kudalkar, CA Rouzer, LJ Marnett Heme Peroxidases by Emma Raven, Brian Dunford,, 245-271, 2015 | 63* | 2015 |
| Covalent inhibitors for eradication of drug-resistant HIV-1 reverse transcriptase: From design to protein crystallography AH Chan, WG Lee, KA Spasov, JA Cisneros, SN Kudalkar, ZO Petrova, ... Proceedings of the National Academy of Sciences 114 (36), 9725-9730, 2017 | 55 | 2017 |
| From in silico hit to long-acting late-stage preclinical candidate to combat HIV-1 infection SN Kudalkar, J Beloor, E Quijano, KA Spasov, WG Lee, JA Cisneros, ... Proceedings of the National Academy of Sciences 115 (4), E802-E811, 2018 | 34 | 2018 |
| Action at a Distance: Mutations of Peripheral Residues Transform Rapid Reversible Inhibitors to Slow, Tight Binders of Cyclooxygenase-2 AL Blobaum, S Xu, SW Rowlinson, KC Duggan, S Banerjee, SN Kudalkar, ... The Journal of Biological Chemistry 290, 12793-12803, 2015 | 33 | 2015 |
| 13-Methylarachidonic acid is a positive allosteric modulator of endocannabinoid oxygenation by cyclooxygenase SN Kudalkar, SP Nikas, PJ Kingsley, S Xu, JJ Galligan, CA Rouzer, ... Journal of Biological Chemistry 290 (12), 7897-7909, 2015 | 27 | 2015 |
| (R)-N-(1-Methyl-2-hydroxyethyl)-13-(S)-methyl-arachidonamide (AMG315): A Novel Chiral Potent Endocannabinoid Ligand with Stability to Metabolizing Enzymes Journal of Medicinal Chemistry, 2018 | 22 | 2018 |
| Structural and pharmacological evaluation of a novel non-nucleoside reverse transcriptase inhibitor as a promising long acting nanoformulation for treating HIV SN Kudalkar, I Ullah, N Bertoletti, HK Mandl, JA Cisneros, J Beloor, ... Antiviral research 167, 110-116, 2019 | 17 | 2019 |
| Structural and preclinical studies of computationally designed non-nucleoside reverse transcriptase inhibitors for treating HIV infection SN Kudalkar, J Beloor, AH Chan, WG Lee, WL Jorgensen, P Kumar, ... Molecular pharmacology 91 (4), 383-391, 2017 | 17 | 2017 |
| Enhancing the peroxidatic activity of KatG by deletion mutagenesis SN Kudalkar, RA Campbell, Y Li, CL Varnado, C Prescott, DC Goodwin Journal of Inorganic Biochemistry 116, 106-115, 2012 | 17 | 2012 |
| Structure-guided identification of DNMT3b inhibitors AS Newton, JC Faver, G Micevic, V Muthusamy, SN Kudalkar, N Bertoletti, ... ACS Medicinal Chemistry Letters 11 (5), 971-976, 2020 | 15 | 2020 |
| Assay of Endocannabinoid Oxidation by Cyclooxygenase-2 SN Kudalkar, P Kingsley, LJ Marnett Endocannabinoid Signaling- Methods and Protocols 1412, 205-215, 2016 | 14* | 2016 |
| A role for catalase-peroxidase large loop 2 revealed by deletion mutagenesis: control of active site water and ferric enzyme reactivity SN Kudalkar, OJ Njuma, Y Li, M Muldowney, NR Fuanta, DC Goodwin Biochemistry 54 (8), 1648-1662, 2015 | 9 | 2015 |
| Potent Noncovalent Inhibitors of the Main Protease of SARS-CoV-2 from Molecular Sculpting of the Drug Perampanel Guided by Free Energy Perturbation Calculations. ACS Cent. Sci … CH Zhang, EA Stone, M Deshmukh, JA Ippolito, MM Ghahremanpour, ... DOI: https://doi. org/10.1021/acscentsci. 1c00039. PMID: https://www. ncbi …, 0 | 9 | |
| DRONE: Direct tracking of DNA cytidine deamination and other DNA modifying activities T Sasaki, S Kudalkar, N Bertoletti, K Anderson Analytical Chemistry, 2018 | 6 | 2018 |
| Long‐acting and extended‐release implant and nanoformulations with a synergistic antiretroviral two‐drug combination controls HIV‐1 infection in a humanized mouse model J Beloor, SN Kudalkar, G Buzzelli, F Yang, HK Mandl, JK Rajashekar, ... Bioengineering & Translational Medicine 7 (1), e10237, 2022 | 5 | 2022 |
| Molecular and cellular studies evaluating a potent 2-cyanoindolizine catechol diether NNRTI targeting wildtype and Y181C mutant HIV-1 reverse transcriptase T Sasaki, ZTK Gannam, SN Kudalkar, KM Frey, WG Lee, KA Spasov, ... Bioorganic & medicinal chemistry letters 29 (16), 2182-2188, 2019 | 4 | 2019 |
| Potent noncovalent inhibitors of the main protease of SARS-CoV-2 from molecular sculpting of the drug perampanel guided by free energy perturbation calculations, ACS Cent. Sci … CH Zhang, EA Stone, M Deshmukh, JA Ippolito, MM Ghahremanpour, ... | 4 | |
| The Structural Basis of Cyclooxygenase‐2 Inhibition by Fenamates S Xu, S Banerjee, SN Kudalkar, ET Perry, K Ghebreselasie, LJ Marnett The FASEB Journal 30, 842.6-842.6, 2016 | 2 | 2016 |
| Roles of Large Loops in Catalytic Versatility of Catalase-Peroxidases: Significance of Peripheral Structures in Improvising Enzyme Functions SN Kudalkar | 2 | 2012 |
William L. JorgensenSterling Professor of Chemistry, Yale UniversityVerified email at yale.edu
