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Brigita Urbanc
Brigita Urbanc
Professor of Physics & Associate Head for Graduate Studies, Drexel University
Geverifieerd e-mailadres voor drexel.edu
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In silico study of amyloid β-protein folding and oligomerization
B Urbanc, L Cruz, S Yun, SV Buldyrev, G Bitan, DB Teplow, HE Stanley
Proceedings of the National Academy of Sciences 101 (50), 17345-17350, 2004
4162004
Plaque-induced neurite abnormalities: implications for disruption of neural networks in Alzheimer’s disease
RB Knowles, C Wyart, SV Buldyrev, L Cruz, B Urbanc, ME Hasselmo, ...
Proceedings of the National Academy of Sciences 96 (9), 5274-5279, 1999
3101999
Neurotoxic effects of thioflavin S-positive amyloid deposits in transgenic mice and Alzheimer's disease
B Urbanc, L Cruz, R Le, J Sanders, KH Ashe, K Duff, HE Stanley, ...
Proceedings of the National Academy of Sciences 99 (22), 13990-13995, 2002
2762002
Elucidation of amyloid β-protein oligomerization mechanisms: discrete molecular dynamics study
B Urbanc, M Betnel, L Cruz, G Bitan, DB Teplow
Journal of the American Chemical Society 132 (12), 4266-4280, 2010
2692010
Elucidating amyloid β-protein folding and assembly: a multidisciplinary approach
DB Teplow, ND Lazo, G Bitan, S Bernstein, T Wyttenbach, MT Bowers, ...
Accounts of chemical research 39 (9), 635-645, 2006
2632006
Molecular dynamics simulation of amyloid β dimer formation
B Urbanc, L Cruz, F Ding, D Sammond, S Khare, SV Buldyrev, HE Stanley, ...
Biophysical journal 87 (4), 2310-2321, 2004
2492004
C-terminal peptides coassemble into Aβ42 oligomers and protect neurons against Aβ42-induced neurotoxicity
EA Fradinger, BH Monien, B Urbanc, A Lomakin, M Tan, H Li, SM Spring, ...
Proceedings of the National Academy of Sciences 105 (37), 14175-14180, 2008
2112008
Role of electrostatic interactions in amyloid β-protein (Aβ) oligomer formation: a discrete molecular dynamics study
S Yun, B Urbanc, L Cruz, G Bitan, DB Teplow, HE Stanley
Biophysical journal 92 (11), 4064-4077, 2007
1652007
Folding events in the 21-30 region of amyloid β-protein (Aβ) studied in silico
JM Borreguero, B Urbanc, ND Lazo, SV Buldyrev, DB Teplow, HE Stanley
Proceedings of the National Academy of Sciences 102 (17), 6015-6020, 2005
1512005
Solvent and mutation effects on the nucleation of amyloid β-protein folding
L Cruz, B Urbanc, JM Borreguero, ND Lazo, DB Teplow, HE Stanley
Proceedings of the National Academy of Sciences 102 (51), 18258-18263, 2005
1442005
Dimer formation enhances structural differences between amyloid β-protein (1–40) and (1–42): an explicit-solvent molecular dynamics study
B Barz, B Urbanc
PloS one 7 (4), e34345, 2012
1352012
Aggregation and disaggregation of senile plaques in Alzheimer disease
L Cruz, B Urbanc, SV Buldyrev, R Christie, T Gómez-Isla, S Havlin, ...
Proceedings of the National Academy of Sciences 94 (14), 7612-7616, 1997
1341997
Description of microcolumnar ensembles in association cortex and their disruption in Alzheimer and Lewy body dementias
SV Buldyrev, L Cruz, T Gomez-Isla, E Gomez-Tortosa, S Havlin, R Le, ...
Proceedings of the National Academy of Sciences 97 (10), 5039-5043, 2000
1232000
Plaque-induced abnormalities in neurite geometry in transgenic models of Alzheimer disease: implications for neural system disruption
R Le, L Cruz, B Urbanc, RB Knowles, K Hsiao-Ashe, K Duff, MC Irizarry, ...
Journal of Neuropathology & Experimental Neurology 60 (8), 753-758, 2001
1152001
Aβ42 oligomers, but not fibrils, simultaneously bind to and cause damage to ganglioside-containing lipid membranes
TL Williams, BRG Johnson, B Urbanc, ATA Jenkins, SDA Connell, ...
Biochemical Journal 439 (1), 67-77, 2011
1132011
Discrete molecular dynamics simulations of peptide aggregation
S Peng, F Ding, B Urbanc, SV Buldyrev, L Cruz, HE Stanley, ...
Physical Review E 69 (4), 041908, 2004
1032004
Effects of the Arctic (E22→G) Mutation on Amyloid β-Protein Folding: Discrete Molecular Dynamics Study
AR Lam, DB Teplow, HE Stanley, B Urbanc
Journal of the American Chemical Society 130 (51), 17413-17422, 2008
932008
Amyloid-Protein Aggregation: Ab Initio Discrete Molecular Dynamics Approaches
B Urbanc, JM Borreguero, L Cruz, HE Stanley
Meth. Enzymol 412, 314-338, 2006
90*2006
Dynamics of plaque formation in Alzheimer's disease
B Urbanc, L Cruz, SV Buldyrev, S Havlin, MC Irizarry, HE Stanley, ...
Biophysical journal 76 (3), 1330-1334, 1999
851999
pH-Independence of trialanine and the effects of termini blocking in short peptides: a combined vibrational, NMR, UVCD, and molecular dynamics study
S Toal, D Meral, D Verbaro, B Urbanc, R Schweitzer-Stenner
The Journal of Physical Chemistry B 117 (14), 3689-3706, 2013
772013
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Artikelen 1–20