Bin Fang

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Mitchell A. LazarWillard and Rhoda Ware Professor of Diabetes and Metabolic Diseases, University of PennsylvaniaAdresse e-mail validée de pennmedicine.upenn.edu
Manashree DamleMassachusetts General HospitalAdresse e-mail validée de molbio.mgh.harvard.edu
Yuxiang ZhangBoston Children's Hospital / Howard Hughes Medical InstituteAdresse e-mail validée de childrens.harvard.edu
David StegerDirector of Discovery Research, Gene Therapy Program, University of PennsylvaniaAdresse e-mail validée de upenn.edu
Logan J EverettEnvironmental Protection AgencyAdresse e-mail validée de epa.gov
Irene WeberGeorgia State UniversityAdresse e-mail validée de gsu.edu
Kyoung Jae WonUniversity of CopenhagenAdresse e-mail validée de bric.ku.dk
dongyin guanBaylor College of MedicineAdresse e-mail validée de case.edu
Frances SladekUniversity of California RiversideAdresse e-mail validée de ucr.edu
Matthew J. Emmett, MD, PhDHematology/Oncology Fellow, Dana-Farber Cancer Institute, Mass General BrighamAdresse e-mail validée de partners.org
Hee-Woong LimAssistant Professor, Division of Biomedical Informatics, Cincinnati Children's HospitalAdresse e-mail validée de cchmc.org
Eugene BolotinSanta Ana BioAdresse e-mail validée de santaanabio.com
Sean M. Armour, Ph.D.Head of DiscoveryAdresse e-mail validée de sparktx.com
Zach Gerhart-HinesUniversity of CopenhagenAdresse e-mail validée de sund.ku.dk
Eric R. ChenFlaum Eye Institute, University of Rochester Medical CenterAdresse e-mail validée de urmc.rochester.edu
Jarrett R. RemsbergThe Scripps Research InstituteAdresse e-mail validée de scripps.edu
Guoxing FuPh.D.Adresse e-mail validée de student.gsu.edu
Robert HarrisonProfessor of computer science, georgia state universityAdresse e-mail validée de cs.gsu.edu
Tao JiangUC RiversideAdresse e-mail validée de cs.ucr.edu
József TőzsérDepartment of Biochemistry and Molecular Biology, Faculty of Medicine, University of DebrecenAdresse e-mail validée de med.unideb.hu

Suivre

Bin Fang

Genomics Institute of Novartis Research Fundation

Adresse e-mail validée de gnf.org

Bioinformatics Investigator


Titre Trier par citations Trier par année Trier par titre	Citée par Citée par	Année
Discrete functions of nuclear receptor Rev-erbα couple metabolism to the clock Y Zhang, B Fang, MJ Emmett, M Damle, Z Sun, D Feng, SM Armour, ... Science 348 (6242), 1488-1492, 2015	261	2015
Deacetylase-independent function of HDAC3 in transcription and metabolism requires nuclear receptor corepressor Z Sun, D Feng, B Fang, SE Mullican, SH You, HW Lim, LJ Everett, ... Molecular cell 52 (6), 769-782, 2013	221	2013
Circadian enhancers coordinate multiple phases of rhythmic gene transcription in vivo B Fang, LJ Everett, J Jager, E Briggs, SM Armour, D Feng, A Roy, ... Cell 159 (5), 1140-1152, 2014	192	2014
Genetic Variation Determines PPARγ Function and Anti-diabetic Drug Response In Vivo LMA Soccio RE, Chen ER, Rajapurkar SR, Safabakhsh P, Marinis JM, Dispirito ... cell 162 (1), 33-44, 2015	122	2015
Diet-induced circadian enhancer remodeling synchronizes opposing hepatic lipid metabolic processes D Guan, Y Xiong, PC Borck, C Jang, PT Doulias, R Papazyan, B Fang, ... Cell 174 (4), 831-842. e12, 2018	117	2018
Identification of a binding motif specific to HNF4 by comparative analysis of multiple nuclear receptors B Fang, D Mane-Padros, E Bolotin, T Jiang, FM Sladek Nucleic Acids Research 40 (12), 5343-5356, 2012	110	2012
Dissociation of muscle insulin sensitivity from exercise endurance in mice by HDAC3 depletion S Hong, W Zhou, B Fang, W Lu, E Loro, M Damle, G Ding, J Jager, ... Nature Medicine, 2016	74	2016
Structural and kinetic analysis of caspase-3 reveals role for s5 binding site in substrate recognition B Fang, PI Boross, J Tozser, IT Weber Journal of molecular biology 360 (3), 654-666, 2006	68	2006
Behavioral changes and dopaminergic dysregulation in mice lacking the nuclear receptor Rev-erbα J Jager, WT O'Brien, J Manlove, EN Krizman, B Fang, Z Gerhart-Hines, ... Molecular endocrinology 28 (4), 490-498, 2014	65	2014
Plasticity of S2–S4 specificity pockets of executioner caspase‐7 revealed by structural and kinetic analysis J Agniswamy, B Fang, IT Weber The FEBS Journal 274 (18), 4752-4765, 2007	60	2007
Tropifexor‐mediated abrogation of steatohepatitis and fibrosis is associated with the antioxidative gene expression profile in rodents ED Hernandez, L Zheng, Y Kim, B Fang, B Liu, RA Valdez, WF Dietrich, ... Hepatology communications 3 (8), 1085-1097, 2019	56	2019
Differential effects of hepatocyte nuclear factor 4α isoforms on tumor growth and T-cell factor 4/AP-1 interactions in human colorectal cancer cells LM Vuong, K Chellappa, JM Dhahbi, JR Deans, B Fang, E Bolotin, ... Molecular and Cellular Biology 35 (20), 3471-3490, 2015	56	2015
The hepatic circadian clock fine-tunes the lipogenic response to feeding through RORα/γ Y Zhang, R Papazyan, M Damle, B Fang, J Jager, D Feng, LC Peed, ... Genes & Development 31 (12), 1202-1211, 2017	53	2017
HNF6 and Rev-erbα integrate hepatic lipid metabolism by overlapping and distinct transcriptional mechanisms Y Zhang, B Fang, M Damle, D Guan, Z Li, YH Kim, M Gannon, MA Lazar Genes & development 30 (14), 1636-1644, 2016	53	2016
Stimulus-cleavable chemistry in the field of controlled drug delivery Y Xue, H Bai, B Peng, B Fang, J Baell, L Li, W Huang, NH Voelcker Chemical Society Reviews 50 (8), 4872-4931, 2021	46	2021
Structural basis for executioner caspase recognition of P5 position in substrates G Fu, AA Chumanevich, J Agniswamy, B Fang, RW Harrison, IT Weber Apoptosis 13 (11), 1291-1302, 2008	38	2008
Caspase-3 binds diverse P4 residues in peptides as revealed by crystallography and structural modeling B Fang, G Fu, J Agniswamy, RW Harrison, IT Weber Apoptosis 14 (5), 741-752, 2009	33	2009
The nuclear receptor Rev-erbα regulates adipose tissue-specific FGF21 signaling J Jager, F Wang, B Fang, HW Lim, LC Peed, DJ Steger, KJ Won, ... Journal of Biological Chemistry 291 (20), 10867-10875, 2016	32	2016
Caspases: structure-guided design of drugs to control cell death IT Weber, B Fang, J Agniswamy Mini reviews in medicinal chemistry 8 (11), 1154-1162, 2008	31	2008
Genetic backgrounds determine brown remodeling of white fat in rodents G Ferrannini, M Namwanje, B Fang, M Damle, D Li, Q Liu, MA Lazar, ... Molecular metabolism 5 (10), 948-958, 2016	30	2016

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