Nicholas Waglechner
Nicholas Waglechner
Sinai Health System
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CARD 2017: expansion and model-centric curation of the comprehensive antibiotic resistance database
B Jia, AR Raphenya, B Alcock, N Waglechner, P Guo, KK Tsang, BA Lago, ...
Nucleic acids research, gkw1004, 2016
The comprehensive antibiotic resistance database
AG McArthur, N Waglechner, F Nizam, A Yan, MA Azad, AJ Baylay, ...
Antimicrobial agents and chemotherapy 57 (7), 3348-3357, 2013
Antibiotic resistance is prevalent in an isolated cave microbiome
K Bhullar, N Waglechner, A Pawlowski, K Koteva, ED Banks, ...
PloS one 7 (4), e34953, 2012
A draft genome of Yersinia pestis from victims of the Black Death
KI Bos, VJ Schuenemann, GB Golding, HA Burbano, N Waglechner, ...
Nature 478 (7370), 506-510, 2011
Yersinia pestis and the Plague of Justinian 541–543 AD: a genomic analysis
DM Wagner, J Klunk, M Harbeck, A Devault, N Waglechner, JW Sahl, ...
The Lancet infectious diseases 14 (4), 319-326, 2014
IslandViewer 3: more flexible, interactive genomic island discovery, visualization and analysis
BK Dhillon, MR Laird, JA Shay, GL Winsor, R Lo, F Nizam, SK Pereira, ...
Nucleic acids research 43 (W1), W104-W108, 2015
Identifying producers of antibacterial compounds by screening for antibiotic resistance
MN Thaker, W Wang, P Spanogiannopoulos, N Waglechner, AM King, ...
Nature biotechnology 31 (10), 922-927, 2013
The prehistory of antibiotic resistance
J Perry, N Waglechner, G Wright
Cold Spring Harbor perspectives in medicine 6 (6), a025197, 2016
Evolution-guided discovery of antibiotics that inhibit peptidoglycan remodelling
EJ Culp, N Waglechner, W Wang, AA Fiebig-Comyn, YP Hsu, K Koteva, ...
Nature 578 (7796), 582-587, 2020
Eighteenth century Yersinia pestis genomes reveal the long-term persistence of an historical plague focus
KI Bos, A Herbig, J Sahl, N Waglechner, M Fourment, SA Forrest, J Klunk, ...
Elife 5, e12994, 2016
Second-pandemic strain of Vibrio cholerae from the Philadelphia cholera outbreak of 1849
AM Devault, GB Golding, N Waglechner, JM Enk, M Kuch, JH Tien, M Shi, ...
New England Journal of Medicine 370 (4), 334-340, 2014
Clinical utilization of genomics data produced by the international Pseudomonas aeruginosa consortium
L Freschi, J Jeukens, I Kukavica-Ibrulj, B Boyle, MJ Dupont, J Laroche, ...
Frontiers in microbiology 6, 1036, 2015
Antibiotic resistance: it’s bad, but why isn’t it worse?
N Waglechner, GD Wright
BMC biology 15, 1-8, 2017
Bacterial inactivation of the anticancer drug doxorubicin
EL Westman, MJ Canova, IJ Radhi, K Koteva, I Kireeva, N Waglechner, ...
Chemistry & biology 19 (10), 1255-1264, 2012
Hidden antibiotics in actinomycetes can be identified by inactivation of gene clusters for common antibiotics
EJ Culp, G Yim, N Waglechner, W Wang, AC Pawlowski, GD Wright
Nature Biotechnology 37 (10), 1149-1154, 2019
A small molecule discrimination map of the antibiotic resistance kinome
T Shakya, PJ Stogios, N Waglechner, E Evdokimova, L Ejim, ...
Chemistry & Biology 18 (12), 1591-1601, 2011
Phylogenetic reconciliation reveals the natural history of glycopeptide antibiotic biosynthesis and resistance
N Waglechner, AG McArthur, GD Wright
Nature microbiology 4 (11), 1862-1871, 2019
A cryptic polyene biosynthetic gene cluster in Streptomyces calvus is expressed upon complementation with a functional bldA gene
L Kalan, A Gessner, MN Thaker, N Waglechner, XM Zhu, A Szawiola, ...
Chemistry & biology 20 (10), 1214-1224, 2013
Inactivation of the lipopeptide antibiotic daptomycin by hydrolytic mechanisms
VM D'Costa, TA Mukhtar, T Patel, K Koteva, N Waglechner, DW Hughes, ...
Antimicrobial agents and chemotherapy 56 (2), 757-764, 2012
A rifamycin inactivating phosphotransferase family shared by environmental and pathogenic bacteria
P Spanogiannopoulos, N Waglechner, K Koteva, GD Wright
Proceedings of the National Academy of Sciences 111 (19), 7102-7107, 2014
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