A bioimage informatics based reconstruction of breast tumor microvasculature with computational blood flow predictions SK Stamatelos, E Kim, AP Pathak, AS Popel Microvascular research 91, 8-21, 2014 | 102 | 2014 |
Multiscale imaging and computational modeling of blood flow in the tumor vasculature E Kim, S Stamatelos, J Cebulla, ZM Bhujwalla, AS Popel, AP Pathak Annals of biomedical engineering 40, 2425-2441, 2012 | 76 | 2012 |
Tumor ensemble-based modeling and visualization of emergent angiogenic heterogeneity in breast cancer SK Stamatelos, A Bhargava, E Kim, AS Popel, AP Pathak Scientific reports 9 (1), 5276, 2019 | 28 | 2019 |
Mathematical model of uptake and metabolism of arsenic (III) in human hepatocytes-Incorporation of cellular antioxidant response and threshold-dependent behavior SK Stamatelos, CJ Brinkerhoff, SS Isukapalli, PG Georgopoulos BMC systems biology 5, 1-15, 2011 | 21 | 2011 |
Predicting In Vivo Efficacy from In Vitro Data: Quantitative Systems Pharmacology Modeling for an Epigenetic Modifier Drug in Cancer M Bouhaddou, LJ Yu, S Lunardi, SK Stamatelos, F Mack, JM Gallo, ... Clinical and Translational Science 13 (2), 419-429, 2020 | 20 | 2020 |
A semi-mechanistic integrated toxicokinetic–toxicodynamic (TK/TD) model for arsenic (III) in hepatocytes SK Stamatelos, IP Androulakis, ANT Kong, PG Georgopoulos Journal of theoretical biology 317, 244-256, 2013 | 14 | 2013 |
From cold to hot: changing perceptions and future opportunities for quantitative systems pharmacology modeling in cancer immunotherapy V Lemaire, D Bassen, M Reed, R Song, S Khalili, YT Lien, L Huang, ... Clinical Pharmacology & Therapeutics 113 (5), 963-972, 2023 | 9 | 2023 |
Quantitative systems pharmacology modeling sheds light into the dose response relationship of a trispecific T cell engager in multiple myeloma RE Abrams, K Pierre, N El-Murr, E Seung, L Wu, E Luna, R Mehta, J Li, ... Scientific Reports 12 (1), 10976, 2022 | 7 | 2022 |
Image‐based Characterization of Functional and Structural Heterogeneity of Tumor Xenografts using Blood Flow modeling, Oxygenation Modeling and Multivariate Analysis S Stamatelos, E Kim, A Pathak, A Popel The FASEB Journal 29, 787.11, 2015 | 1 | 2015 |
Abstract CT276: Preliminary analysis of pharmacokinetic (PK) and target engagement biomarkers from a first in human phase 1 study of immunomodulatory aryl hydrocarbon receptor … K Papadopoulos, M Cecchini, JS Lopez, D Jäger, KY Chung, M Platten, ... Cancer Research 83 (8_Supplement), CT276-CT276, 2023 | | 2023 |
PREDICTING DRUG EFFICACY AND CYTOKINE RELEASE WITH A VERSATILE QUANTITATIVE SYSTEMS PHARMACOLOGY (QSP) MODELING STRATEGY FOR MULTISPECIFIC T-CELL ENGAGERS. R Abrams, K Pierre, N El-Murr, A Li, J Fretland, J Li, L Wu, E Seung, ... CLINICAL PHARMACOLOGY & THERAPEUTICS 107, S114-S114, 2020 | | 2020 |
Development of a multiscale QSP model to characterize the tumor suppressive effects of a cytokine mRNA immunotherapy in a preclinical melanoma mouse model K Pierre, L Lin, L Gruenbaum, C Young, J Apgar, C Hotz, T Wagenaar, ... Cancer Research 79 (13_Supplement), 685-685, 2019 | | 2019 |
Development of an Integrated Human Model of Electrophysiology and Actin-Myosin Binding to Describe Sarcomere Force Generation in Cardiomyocytes RE Abrams, HC Schneider, T Radziun, B Goebel, L Lucats, K Azer, ... Biophysical Journal 116 (3), 422a-423a, 2019 | | 2019 |
Development of a multiscale model for heart failure focusing on cardiac myosin modulators SK Stamatelos, R Abrams, E Sobie, L Lucats, H Surks, ... JOURNAL OF PHARMACOKINETICS AND PHARMACODYNAMICS 45, S125-S125, 2018 | | 2018 |
Predicting in vivo efficacy from in vitro data: Quantitative systems pharmacology modeling for an epigenetic modifier drug in cancer M Bouhaddou, LJ Yu, S Lunardi, SK Stamatelos, F Mack, JM Gallo, ... Cancer Research 78 (13_Supplement), 2796-2796, 2018 | | 2018 |
Characterization of tumor heterogeneity using bioimage informatics and 3D computational modeling S Stamatelos, A Carlier, E Kim, A Pathak, A Popel Meeting of the Biomedical Engineering Society, 2013 | | 2013 |
Identification of morphological and hemodynamic biomarkers for tumor vascular perfusion through mathematical modeling and high‐resolution imaging SK Stamatelos, E Kim, AP Pathak, AS Popel The FASEB Journal 27, 685.12-685.12, 2013 | | 2013 |
In Silico Modeling of Uptake and Metabolism of Arsenicals In Hepatocytes with Implications for Hepatotoxicity SK Stamatelos, CJ Brinkerhoff, AF Sasso, SS Isukapalli, ... 2008 AIChE Annual Meeting, AIChE 100, 2008 | | 2008 |
Population Approach Group Europe Population Approach Group Europe S Stamatelos | | |
765a In Silico Modeling of Uptake and Metabolism of Arsenicals In Hepatocytes with Implications for Hepatotoxicity SK Stamatelos | | |