Potent Noncovalent Inhibitors of the Main Protease of SARS-CoV-2 from Molecular Sculpting of the Drug Perampanel Guided by Free Energy Perturbation Calculations CH Zhang, EA Stone, M Deshmukh, JA Ippolito, MM Ghahremanpour, ... ACS central science 7 (3), 467-475, 2021 | 214 | 2021 |
Asymmetric Catalysis Mediated by Synthetic Peptides, Version 2.0: Expansion of Scope and Mechanisms AJ Metrano, AJ Chinn, CR Shugrue, EA Stone, B Kim, SJ Miller Chemical Reviews 120 (20), 11479-11615, 2020 | 126 | 2020 |
Parameterization and Analysis of Peptide-Based Catalysts for the Atroposelective Bromination of 3-Arylquinazolin-4(3H)-ones JM Crawford, EA Stone, AJ Metrano, SJ Miller, MS Sigman Journal of the American Chemical Society 140 (3), 868-871, 2018 | 64 | 2018 |
Structure-guided design of a perampanel-derived pharmacophore targeting the SARS-CoV-2 main protease KSA MG Deshmukh, JA Ippolito, CH Zhang, EA Stone, RA Reilly, SJ Miller, WL ... Structure 29 (6), P823–833, 2021 | 52 | 2021 |
Terahertz spectroscopy of tetrameric peptides J Neu, EA Stone, JA Spies, G Storch, AS Hatano, BQ Mercado, SJ Miller, ... The journal of physical chemistry letters 10 (10), 2624-2628, 2019 | 49 | 2019 |
Optimization of triarylpyridinone inhibitors of the main protease of SARS-CoV-2 to low-nanomolar antiviral potency CH Zhang, KA Spasov, RA Reilly, K Hollander, EA Stone, JA Ippolito, ... ACS Medicinal Chemistry Letters 12 (8), 1325-1332, 2021 | 47 | 2021 |
Desymmetrization of Diarylmethylamido Bis (phenols) through Peptide-Catalyzed Bromination: Enantiodivergence as a Consequence of a 2 amu Alteration at an Achiral Residue within … AE Hurtley, EA Stone, AJ Metrano, SJ Miller The Journal of organic chemistry 82 (21), 11326-11336, 2017 | 39 | 2017 |
Catalytic Enantioselective Pyridine N-Oxidation SY Hsieh, Y Tang, S Crotti, EA Stone, SJ Miller Journal of the American Chemical Society 141 (46), 18624-18629, 2019 | 35 | 2019 |
Asymmetric Catalysis upon Helically Chiral Loratadine Analogues Unveils Enantiomer-Dependent Antihistamine Activity EA Stone, KJ Cutrona, SJ Miller Journal of the American Chemical Society 142 (29), 12690-12698, 2020 | 20 | 2020 |
Troponoid Atropisomerism: Studies on the Configurational Stability of Tropone-Amide Chiral Axes DR Hirsch, AJ Metrano, EA Stone, G Storch, SJ Miller, RP Murelli Organic letters 21 (7), 2412-2415, 2019 | 18 | 2019 |
Isolating Conformers to Assess Dynamics of Peptidic Catalysts Using Computationally Designed Macrocyclic Peptides EA Stone, P Hosseinzadeh, TW Craven, MJ Robertson, Y Han, SY Hsieh, ... ACS Catalysis 11 (8), 4395-4400, 2021 | 13 | 2021 |
Utilization of the Thorpe–Ingold Effect in the Synthesis of Cyclooctanoid Ring Systems via Anionic 6-exo-dig Cyclization/Claisen Rearrangement Sequence WC DeLomba, EA Stone, KA Alley, V Iannarone, E Tarsis, S Ovaska, ... The Journal of Organic Chemistry 85 (15), 9464-9474, 2020 | 12 | 2020 |
Structure and Reactivity of Highly Twisted N-Acylimidazoles EA Stone, BQ Mercado, SJ Miller Organic letters 21 (7), 2346-2351, 2019 | 11 | 2019 |
On the Ability of the N–O Bond to Support a Stable Stereogenic Axis: Peptide-Catalyzed Atroposelective N-Oxidation SE Huth, EA Stone, S Crotti, SJ Miller The Journal of Organic Chemistry 88 (17), 12857-12862, 2023 | 1 | 2023 |