| Diazepam-bound GABAA receptor models identify new benzodiazepine binding-site ligands L Richter, C De Graaf, W Sieghart, Z Varagic, M Mörzinger, IJP De Esch, ... Nature chemical biology 8 (5), 455, 2012 | 234 | 2012 |
| The benzodiazepine binding sites of GABAA receptors E Sigel, M Ernst Trends in pharmacological sciences 39 (7), 659-671, 2018 | 231 | 2018 |
| Comparative modeling of GABAA receptors: limits, insights, future developments M Ernst, D Brauchart, S Boresch, W Sieghart Neuroscience 119 (4), 933-943, 2003 | 215 | 2003 |
| Comparative models of GABAA receptor extracellular and transmembrane domains: important insights in pharmacology and function M Ernst, S Bruckner, S Boresch, W Sieghart Molecular pharmacology 68 (5), 1291-1300, 2005 | 180 | 2005 |
| Pentameric ligand-gated ion channel ELIC is activated by GABA and modulated by benzodiazepines R Spurny, J Ramerstorfer, K Price, M Brams, M Ernst, H Nury, M Verheij, ... Proceedings of the National Academy of Sciences 109 (44), E3028-E3034, 2012 | 149 | 2012 |
| The GABAA receptor α+ β− interface: a novel target for subtype selective drugs J Ramerstorfer, R Furtmüller, I Sarto-Jackson, Z Varagic, W Sieghart, ... Journal of neuroscience 31 (3), 870-877, 2011 | 133 | 2011 |
| A novel GABAA receptor pharmacology: drugs interacting with the α+ β‐interface W Sieghart, J Ramerstorfer, I Sarto‐Jackson, Z Varagic, M Ernst British journal of pharmacology 166 (2), 476-485, 2012 | 106 | 2012 |
| An updated unified pharmacophore model of the benzodiazepine binding site on γ-aminobutyric acida receptors: correlation with comparative models T Clayton, JL Chen, M Ernst, L Richter, BA Cromer, CJ Morton, H Ng, ... Current medicinal chemistry 14 (26), 2755-2775, 2007 | 101 | 2007 |
| Structural studies of GABAA receptor binding sites: which experimental structure tells us what? R Puthenkalam, M Hieckel, X Simeone, C Suwattanasophon, ... Frontiers in molecular neuroscience 9, 44, 2016 | 90 | 2016 |
| Heterogeneity of GABAA receptors: revived interest in the development of subtype-selective drugs W Sieghart, M Ernst Current Medicinal Chemistry-Central Nervous System Agents 5 (3), 217-242, 2005 | 87 | 2005 |
| Subtype selectivity of α+ β− site ligands of GABAA receptors: identification of the first highly specific positive modulators at α6β2/3γ2 receptors Z Varagic, J Ramerstorfer, S Huang, S Rallapalli, I Sarto‐Jackson, J Cook, ... British journal of pharmacology 169 (2), 384-399, 2013 | 77 | 2013 |
| GABAA Receptors M Ernst, F Steudle, K Bampali eLS, 0 | 73* | |
| Computational thermochemistry of medium-sized silicon hydrides G Katzer, MC Ernst, AF Sax, J Kalcher The Journal of Physical Chemistry A 101 (21), 3942-3958, 1997 | 71 | 1997 |
| Affinity of various benzodiazepine site ligands in mice with a point mutation in the GABAA receptor γ2 subunit W Ogris, A Pöltl, B Hauer, M Ernst, A Oberto, P Wulff, H Höger, W Wisden, ... Biochemical pharmacology 68 (8), 1621-1629, 2004 | 64 | 2004 |
| Identification of novel positive allosteric modulators and null modulators at the GABAA receptor α+ β− interface Z Varagic, L Wimmer, M Schnürch, MD Mihovilovic, S Huang, S Rallapalli, ... British journal of pharmacology 169 (2), 371-383, 2013 | 60 | 2013 |
| Accepted Article Z Varagic, L Wimmer, M Schnürch, MD Mihovilovic, S Huang, S Rallapalli, ... | 60* | 2013 |
| Design and Synthesis of Novel Deuterated Ligands Functionally Selective for the γ-Aminobutyric Acid Type A Receptor (GABAAR) α6 Subtype with Improved … DE Knutson, R Kodali, B Divović, M Treven, MR Stephen, NM Zahn, ... Journal of medicinal chemistry, 2018 | 59 | 2018 |
| Ester to amide substitution improves selectivity, efficacy and kinetic behavior of a benzodiazepine positive modulator of GABAA receptors containing the α5 subunit TT Stamenić, MM Poe, S Rehman, A Santrač, B Divović, P Scholze, ... European journal of pharmacology 791, 433-443, 2016 | 47 | 2016 |
| α subunits in GABA A receptors are dispensable for GABA and diazepam action N Wongsamitkul, MC Maldifassi, X Simeone, R Baur, M Ernst, E Sigel Scientific Reports 7 (1), 15498, 2017 | 44 | 2017 |
| Synthesis and Characterization of a Novel γ-Aminobutyric Acid Type A (GABAA) Receptor Ligand That Combines Outstanding Metabolic Stability … MM Poe, KR Methuku, G Li, AR Verma, KA Teske, DC Stafford, LA Arnold, ... Journal of medicinal chemistry 59 (23), 10800-10806, 2016 | 44 | 2016 |
