| Structures of the Middle East respiratory syndrome coronavirus 3C-like protease reveal insights into substrate specificity D Needle, GT Lountos, DS Waugh Acta Crystallographica Section D: Biological Crystallography 71 (5), 1102-1111, 2015 | 120 | 2015 |
| The Crystal Structure of NAD(P)H Oxidase from Lactobacillus sanfranciscensis: Insights into the Conversion of O2 into Two Water Molecules by the Flavoenzyme, GT Lountos, R Jiang, WB Wellborn, TL Thaler, AS Bommarius, AM Orville Biochemistry 45 (32), 9648-9659, 2006 | 114 | 2006 |
| Cellular inhibition of checkpoint kinase 2 (Chk2) and potentiation of camptothecins and radiation by the novel Chk2 inhibitor PV1019 [7-nitro-1H-indole-2-carboxylic acid {4-[1 … AG Jobson, GT Lountos, PL Lorenzi, J Llamas, J Connelly, D Cerna, ... Journal of Pharmacology and Experimental Therapeutics 331 (3), 816-826, 2009 | 112 | 2009 |
| Role of Glu312 in Binding and Positioning of the Substrate for the Hydride Transfer Reaction in Choline Oxidase, O Quaye, GT Lountos, Fan, AM Orville, G Gadda Biochemistry 47 (1), 243-256, 2008 | 109 | 2008 |
| Crystallographic, Spectroscopic, and Computational Analysis of a Flavin C4a−Oxygen Adduct in Choline Oxidase, AM Orville, GT Lountos, S Finnegan, G Gadda, R Prabhakar Biochemistry 48 (4), 720-728, 2009 | 72 | 2009 |
| Atomic resolution structure of the cytoplasmic domain of Yersinia pestis YscU, a regulatory switch involved in type III secretion GT Lountos, BP Austin, S Nallamsetty, DS Waugh Protein Science 18 (2), 467-474, 2009 | 57 | 2009 |
| Utilization of Nitrophenylphosphates and Oxime-Based Ligation for the Development of Nanomolar Affinity Inhibitors of the Yersinia pestis Outer Protein H (YopH … M Bahta, GT Lountos, B Dyas, SE Kim, RG Ulrich, DS Waugh, TR Burke Jr Journal of medicinal chemistry 54 (8), 2933-2943, 2011 | 52 | 2011 |
| Engineering of glycerol dehydrogenase for improved activity towards 1, 3-butanediol H Zhang, GT Lountos, CB Ching, R Jiang Applied microbiology and biotechnology 88, 117-124, 2010 | 39 | 2010 |
| Insights into the allosteric inhibition of the SUMO E2 enzyme Ubc9 WM Hewitt, GT Lountos, K Zlotkowski, SD Dahlhauser, LB Saunders, ... Angewandte Chemie 128 (19), 5797-5801, 2016 | 34 | 2016 |
| Structure of B-DNA with Cations Tethered in the Major Groove, T Moulaei, T Maehigashi, GT Lountos, S Komeda, D Watkins, MP Stone, ... Biochemistry 44 (20), 7458-7468, 2005 | 33 | 2005 |
| Crystal structure of checkpoint kinase 2 in complex with NSC 109555, a potent and selective inhibitor GT Lountos, JE Tropea, D Zhang, AG Jobson, Y Pommier, RH Shoemaker, ... Protein science 18 (1), 92-100, 2009 | 30 | 2009 |
| Identification of a ligand binding hot spot and structural motifs replicating aspects of tyrosyl-DNA phosphodiesterase I (TDP1) phosphoryl recognition by crystallographic … GT Lountos, XZ Zhao, E Kiselev, JE Tropea, D Needle, Y Pommier, ... Nucleic Acids Research 47 (19), 10134-10150, 2019 | 29 | 2019 |
| Overproduction, purification and structure determination of human dual-specificity phosphatase 14 GT Lountos, JE Tropea, S Cherry, DS Waugh Acta Crystallographica Section D: Biological Crystallography 65 (10), 1013-1020, 2009 | 24 | 2009 |
| Structural characterization of inhibitor complexes with checkpoint kinase 2 (Chk2), a drug target for cancer therapy GT Lountos, AG Jobson, JE Tropea, CR Self, G Zhang, Y Pommier, ... Journal of structural biology 176 (3), 292-301, 2011 | 23 | 2011 |
| A rapid oxime linker-based library approach to identification of bivalent inhibitors of the Yersinia pestis protein-tyrosine phosphatase, YopH F Liu, RM Hakami, B Dyas, M Bahta, GT Lountos, DS Waugh, RG Ulrich, ... Bioorganic & medicinal chemistry letters 20 (9), 2813-2816, 2010 | 23 | 2010 |
| Crystal Structures and Functional Studies of T4moD, the Toluene 4-Monooxygenase Catalytic Effector Protein, GT Lountos, KH Mitchell, JM Studts, BG Fox, AM Orville Biochemistry 44 (19), 7131-7142, 2005 | 23 | 2005 |
| Cryo-EM structure of substrate-free E. coli Lon protease provides insights into the dynamics of Lon machinery I Botos, GT Lountos, W Wu, S Cherry, R Ghirlando, AM Kudzhaev, ... Current Research in Structural Biology 1, 13-20, 2019 | 21 | 2019 |
| A small-molecule microarray approach for the identification of E2 enzyme inhibitors in ubiquitin-like conjugation pathways K Zlotkowski, WM Hewitt, RS Sinniah, JE Tropea, D Needle, GT Lountos, ... SLAS DISCOVERY: Advancing Life Sciences R&D 22 (6), 760-766, 2017 | 20 | 2017 |
| Phosphotyrosine substrate sequence motifs for dual specificity phosphatases BM Zhao, SL Keasey, JE Tropea, GT Lountos, BK Dyas, S Cherry, ... Plos one 10 (8), e0134984, 2015 | 20 | 2015 |
| Structure of human dual-specificity phosphatase 27 at 2.38 Å resolution GT Lountos, JE Tropea, DS Waugh Acta Crystallographica Section D: Biological Crystallography 67 (5), 471-479, 2011 | 20 | 2011 |
