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Lutz Tautz, Ph.D.
Lutz Tautz, Ph.D.
Sanford Burnham Prebys Medical Discovery Institute
Geverifieerd e-mailadres voor sanfordburnham.org - Homepage
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Autoimmune-associated lymphoid tyrosine phosphatase is a gain-of-function variant
T Vang, M Congia, MD Macis, L Musumeci, V Orrú, P Zavattari, K Nika, ...
Nature genetics 37 (12), 1317-1319, 2005
8912005
Protein tyrosine phosphatases in autoimmunity
T Vang, AV Miletic, Y Arimura, L Tautz, RC Rickert, T Mustelin
Annu. Rev. Immunol. 26, 29-55, 2008
2092008
The lipid-binding SEC14 domain
K Saito, L Tautz, T Mustelin
Biochimica et Biophysica Acta (BBA)-Molecular and Cell Biology of Lipids …, 2007
1572007
LYP inhibits T-cell activation when dissociated from CSK
T Vang, WH Liu, L Delacroix, S Wu, S Vasile, R Dahl, L Yang, L Musumeci, ...
Nature chemical biology 8 (5), 437-446, 2012
1522012
Protein tyrosine phosphatases: structure, function, and implication in human disease
L Tautz, DA Critton, S Grotegut
Phosphatase Modulators, 179-221, 2013
1412013
Inhibitor of the tyrosine phosphatase STEP reverses cognitive deficits in a mouse model of Alzheimer's disease
J Xu, M Chatterjee, TD Baguley, J Brouillette, P Kurup, D Ghosh, J Kanyo, ...
PLoS biology 12 (8), e1001923, 2014
1382014
Targeting the PTPome in human disease
L Tautz, M Pellecchia, T Mustelin
Expert opinion on therapeutic targets 10 (1), 157-177, 2006
1322006
Covalent decoration of multi-walled carbon nanotubes with silica nanoparticles
M Bottini, L Tautz, H Huynh, E Monosov, N Bottini, MI Dawson, S Bellucci, ...
Chemical communications, 758-760, 2005
1282005
Protein tyrosine phosphatases in T cell physiology
T Mustelin, A Alonso, N Bottini, H Huynh, S Rahmouni, K Nika, ...
Molecular immunology 41 (6-7), 687-700, 2004
1262004
NMR-based techniques in the hit identification and optimisation processes
M Pellecchia, B Becattini, KJ Crowell, R Fattorusso, M Forino, M Fragai, ...
Expert opinion on therapeutic targets 8 (6), 597-611, 2004
982004
Cervix carcinoma is associated with an up-regulation and nuclear localization of the dual-specificity protein phosphatase VHR
R Henkens, P Delvenne, M Arafa, M Moutschen, M Zeddou, L Tautz, ...
BMC cancer 8, 1-9, 2008
802008
Inhibition of Yersinia tyrosine phosphatase by furanyl salicylate compounds
L Tautz, S Bruckner, S Sareth, A Alonso, J Bogetz, N Bottini, M Pellecchia, ...
Journal of Biological Chemistry 280 (10), 9400-9408, 2005
732005
An adamantyl-substituted retinoid-derived molecule that inhibits cancer cell growth and angiogenesis by inducing apoptosis and binds to small heterodimer partner nuclear …
MI Dawson, Z Xia, G Liu, JA Fontana, L Farhana, BB Patel, ...
Journal of medicinal chemistry 50 (11), 2622-2639, 2007
692007
Strategies for developing protein tyrosine phosphatase inhibitors
L Tautz, T Mustelin
Methods 42 (3), 250-260, 2007
662007
The autoimmune-predisposing variant of lymphoid tyrosine phosphatase favors T helper 1 responses
T Vang, J Landskron, MK Viken, N Oberprieler, KM Torgersen, T Mustelin, ...
Human immunology 74 (5), 574-585, 2013
652013
A conserved mechanism for control of human and mouse embryonic stem cell pluripotency and differentiation by shp2 tyrosine phosphatase
D Wu, Y Pang, Y Ke, J Yu, Z He, L Tautz, T Mustelin, S Ding, Z Huang, ...
PLoS One 4 (3), e4914, 2009
642009
Multidentate Small-Molecule Inhibitors of Vaccinia H1-Related (VHR) Phosphatase Decrease Proliferation of Cervix Cancer Cells
S Wu, S Vossius, S Rahmouni, AV Miletic, T Vang, J Vazquez-Rodriguez, ...
Journal of medicinal chemistry 52 (21), 6716-6723, 2009
622009
Low-Molecular-Weight Protein Tyrosine Phosphatases of Bacillus subtilis
L Musumeci, C Bongiorni, L Tautz, RA Edwards, A Osterman, M Perego, ...
Journal of bacteriology 187 (14), 4945-4956, 2005
612005
Yersinia phosphatase induces mitochondrially dependent apoptosis of T cells
S Bruckner, S Rhamouni, L Tautz, JB Denault, A Alonso, B Becattini, ...
Journal of Biological Chemistry 280 (11), 10388-10394, 2005
582005
Dual-specificity phosphatase 3 deficiency or inhibition limits platelet activation and arterial thrombosis
L Musumeci, MJ Kuijpers, K Gilio, A Hego, E Théâtre, L Maurissen, ...
Circulation 131 (7), 656-668, 2015
542015
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Artikelen 1–20