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Keyu Li
Keyu Li
Associate Director, IGM Biosciences Inc.
Geverifieerd e-mailadres voor igmbio.com
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A microfluidic platform for systems pathology: multiparameter single-cell signaling measurements of clinical brain tumor specimens
J Sun, MD Masterman-Smith, NA Graham, J Jiao, J Mottahedeh, DR Laks, ...
Cancer research 70 (15), 6128-6138, 2010
1162010
Anti-MET ImmunoPET for Non–Small Cell Lung Cancer Using Novel Fully Human Antibody Fragments
K Li, R Tavaré, KA Zettlitz, SM Mumenthaler, P Mallick, Y Zhou, JD Marks, ...
Molecular cancer therapeutics 13 (11), 2607-2617, 2014
382014
A fully human scFv phage display library for rapid antibody fragment reformatting
K Li, KA Zettlitz, J Lipianskaya, Y Zhou, JD Marks, P Mallick, RE Reiter, ...
Protein Engineering, Design and Selection 28 (10), 307-316, 2015
352015
Dual transcript and protein quantification in a massive single cell array
S Park, JY Lee, S Hong, SH Lee, IK Dimov, H Lee, S Suh, Q Pan, K Li, ...
Lab on a Chip 16 (19), 3682-3688, 2016
222016
High avidity IgM-based CD20xCD3 bispecific antibody (IGM-2323) for enhanced T-cell dependent killing with minimal cytokine release
R Baliga, K Li, M Manlusoc, P Hinton, D Ng, M Tran, B Shan, H Lu, A Saini, ...
Blood 134, 1574, 2019
112019
IGM-2323: High Avidity IgM-based CD20 x CD3 Bispecific Antibody for Enhanced T-Cell Dependent Killing with Minimal Cytokine Release
R Baliga, K Li, M Manlusoc, PR Hinton, DC Ng, M Tran, B Shan, H Lu, ...
Abstract 1574, 7-10, 2019
62019
Igm-2644, a novel CD38xCD3 bispecific IgM T cell engager demonstrates potent efficacy on myeloma cells with an improved preclinical safety profile
K Li, R Yun, M Chai, P Yakkundi, R Rosete, G Li, L Liu, D Ng, PR Hinton, ...
Blood 140 (Supplement 1), 6010-6011, 2022
42022
Dual-inhibitory domain iCARs improve the efficiency of the AND-NOT gate CAR T strategy
NJ Bangayan, L Wang, G Burton Sojo, M Noguchi, D Cheng, L Ta, ...
Proceedings of the National Academy of Sciences 120 (47), e2312374120, 2023
32023
A Bispecific IgM Antibody Format for Enhanced T cell-Dependent Killing with Minimal Cytokine Release
R Baliga, K Li, M Manlusoc, PR Hinton, DC Ng, MH Tran, B Shan, H Lu, ...
Cancer Res 80 (16 Supplement), 5664-5664, 2020
32020
Novel CD38xCD3 Bispecific IgM T Cell Engager, IGM-2644, Potently Kills Multiple Myeloma Cells Through Complement and T Cell Dependent Mechanisms
K Li, R Yun, M Chai, P Yakkundi, R Rosete, G Li, L Liu, M Li, D Santos, ...
Cancer Research 83 (7_Supplement), 2959-2959, 2023
12023
High valency of IGM-2323, a CD20xCD3 IgM bispecific T cell engager, displaces rituximab binding and induces potent B lymphoma cell killing
KC Hart, K Logronio, M Li, P Yakkundi, M Manlusoc, K Li, PR Hinton, ...
Cancer Research 82 (12), 2022
12022
841P IGM-2323 is a CD20xCD3 IgM bispecific T-cell engager that kills low CD20-expressing and rituximab-resistant B-cell lymphomas
K Li, MF Kotturi, M Manlusoc, R Yun, PR Hinton, K Logronio, R Baliga, ...
Annals of Oncology 32, S778-S779, 2021
12021
Lymphoma cell-killing activity and cytokine release by CD20-directed bispecific IgM antibody-based T-cell engager (IGM-2323).
B Keyt, R Baliga, K Li, M Manlusoc, P Hinton, D Ng, M Tran, B Shan, H Lu, ...
Journal of Clinical Oncology 38 (15_suppl), e15007-e15007, 2020
12020
IGM-2644, a CD38xCD3 bispecific IgM T cell engager, shows enhanced anti-tumor activity compared to daratumumab in preclinical models of multiple myeloma
KC Hart, D Santos, K Li, R Yun, M Chai, A Kabai, G Li, P Yakkundi, ...
Cancer Research 84 (6_Supplement), 1237-1237, 2024
2024
Costimulatory IgM T-cell engagers with enhanced and durable cytotoxicity
J Xue, K Li, P Yakkundi, P Chadasama, T Mao, Z Malik, V Rao, ...
Cancer Research 84 (6_Supplement), 6726-6726, 2024
2024
1174 Costimulatory IgM T-cell engagers with enhanced and durable cytotoxicity
K Li, J Xue, D Pandya, P Yakkundi, G Li, K Mai, N Hanna, Z Ye, R Rosete, ...
Journal for ImmunoTherapy of Cancer 11 (Suppl 1), 2023
2023
P-047 Trial in progress: an open-label, multicenter, phase 1 study for IGM-2644 in participants with relapsed and/or refractory multiple myeloma (RRMM)
R Funke, H Schade, J Berdeja, K Li, M Kotturi, G Hernandez, Y Guan, ...
Clinical Lymphoma Myeloma and Leukemia 23, S60-S61, 2023
2023
P1276: DOSE RESPONSE PROFILE OF IGM-2323, A CD20XCD3 IGM BISPECIFIC T CELL ENGAGER, IN TRANSLATIONAL MODELS SUPPORTS PHASE 2 DOSE SELECTION IN NON-HODGKIN’S LYMPHOMA
MK Leabman, G Hernandez, CM Ng, J Tang, D Pandya, KC Hart, K Li, ...
HemaSphere 6, 1161-1162, 2022
2022
Fully human antibodies and fragments recognizing human c-Met
AM Wu, LI Keyu
US Patent 10,407,503, 2019
2019
Development of fully humanized N-cadherin monoclonal antibodies for treatment of castration resistant prostate cancer
EA Kono, N Kobayashi, K Zettlitz, K Li, J Yamashiro, C Wang, A Wu, ...
Cancer Research 78 (13_Supplement), 1775-1775, 2018
2018
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Artikelen 1–20