Volgen
Brett Knolhoff
Brett Knolhoff
Geverifieerd e-mailadres voor wustl.edu
Titel
Geciteerd door
Geciteerd door
Jaar
CSF1/CSF1R blockade reprograms tumor-infiltrating macrophages and improves response to T-cell checkpoint immunotherapy in pancreatic cancer models
Y Zhu, BL Knolhoff, MA Meyer, TM Nywening, BL West, J Luo, ...
Cancer research 74 (18), 5057-5069, 2014
12972014
Targeting tumor-infiltrating macrophages decreases tumor-initiating cells, relieves immunosuppression, and improves chemotherapeutic responses
JB Mitchem, DJ Brennan, BL Knolhoff, BA Belt, Y Zhu, DE Sanford, ...
Cancer research 73 (3), 1128-1141, 2013
9922013
Targeting focal adhesion kinase renders pancreatic cancers responsive to checkpoint immunotherapy
H Jiang, S Hegde, BL Knolhoff, Y Zhu, JM Herndon, MA Meyer, ...
Nature medicine 22 (8), 851-860, 2016
8832016
Tissue-resident macrophages in pancreatic ductal adenocarcinoma originate from embryonic hematopoiesis and promote tumor progression
Y Zhu, JM Herndon, DK Sojka, KW Kim, BL Knolhoff, C Zuo, DR Cullinan, ...
Immunity 47 (2), 323-338. e6, 2017
7062017
Stromal senescence establishes an immunosuppressive microenvironment that drives tumorigenesis
MK Ruhland, AJ Loza, AH Capietto, X Luo, BL Knolhoff, KC Flanagan, ...
Nature communications 7 (1), 11762, 2016
3712016
Dendritic cell paucity leads to dysfunctional immune surveillance in pancreatic cancer
S Hegde, VE Krisnawan, BH Herzog, C Zuo, MA Breden, BL Knolhoff, ...
Cancer cell 37 (3), 289-307. e9, 2020
3102020
Breast and pancreatic cancer interrupt IRF8-dependent dendritic cell development to overcome immune surveillance
MA Meyer, JM Baer, BL Knolhoff, TM Nywening, RZ Panni, X Su, ...
Nature communications 9 (1), 1250, 2018
1932018
Agonism of CD11b reprograms innate immunity to sensitize pancreatic cancer to immunotherapies
RZ Panni, JM Herndon, C Zuo, S Hegde, GD Hogg, BL Knolhoff, ...
Science translational medicine 11 (499), eaau9240, 2019
1622019
Development of resistance to FAK inhibition in pancreatic cancer is linked to stromal depletion
H Jiang, X Liu, BL Knolhoff, S Hegde, KB Lee, H Jiang, RC Fields, ...
Gut 69 (1), 122-132, 2020
1032020
Antagonizing integrin β3 increases immunosuppression in cancer
X Su, AK Esser, SR Amend, J Xiang, Y Xu, MH Ross, GC Fox, ...
Cancer research 76 (12), 3484-3495, 2016
742016
Constitutive IRAK4 activation underlies poor prognosis and chemoresistance in pancreatic ductal adenocarcinoma
D Zhang, L Li, H Jiang, BL Knolhoff, AC Lockhart, A Wang-Gillam, ...
Clinical cancer research 23 (7), 1748-1759, 2017
692017
SNAIL1 action in tumor cells influences macrophage polarization and metastasis in breast cancer through altered GM-CSF secretion
A Brenot, BL Knolhoff, DG DeNardo, GD Longmore
Oncogenesis 7 (3), 32, 2018
532018
Stromal reprogramming by FAK inhibition overcomes radiation resistance to allow for immune priming and response to checkpoint blockade
VE Lander, JI Belle, NL Kingston, JM Herndon, GD Hogg, X Liu, LI Kang, ...
Cancer discovery 12 (12), 2774-2799, 2022
282022
IRAK4 signaling drives resistance to checkpoint immunotherapy in pancreatic ductal adenocarcinoma
VK Somani, D Zhang, PB Dodhiawala, VE Lander, X Liu, LI Kang, ...
Gastroenterology 162 (7), 2047-2062, 2022
192022
Context-dependent activation of STING-interferon signaling by CD11b agonists enhances anti-tumor immunity
X Liu, GD Hogg, C Zuo, NC Borcherding, JM Baer, VE Lander, LI Kang, ...
Cancer Cell 41 (6), 1073-1090. e12, 2023
162023
Stromal and therapy-induced macrophage proliferation promotes PDAC progression and susceptibility to innate immunotherapy
C Zuo, JM Baer, BL Knolhoff, JI Belle, X Liu, A Alarcon De La Lastra, C Fu, ...
Journal of Experimental Medicine 220 (6), e20212062, 2023
112023
Fibrosis induced by resident macrophages has divergent roles in pancreas inflammatory injury and PDAC
JM Baer, C Zuo, LI Kang, AA de la Lastra, NC Borcherding, BL Knolhoff, ...
Nature immunology 24 (9), 1443-1457, 2023
102023
BH3-only proteins contribute to steatotic liver ischemia–reperfusion injury
BJ DuBray Jr, KD Conzen, GA Upadhya, KL Gunter, J Jia, BL Knolhoff, ...
journal of surgical research 194 (2), 653-658, 2015
102015
Tumor-associated fibrosis impairs immune surveillance and response to immune checkpoint blockade in non–small cell lung cancer
BH Herzog, JM Baer, N Borcherding, NL Kingston, JI Belle, BL Knolhoff, ...
Science translational medicine 15 (699), eadh8005, 2023
92023
Pancreas resident macrophage-induced fibrosis has divergent roles in pancreas inflammatory injury and PDAC
JM Baer, C Zuo, LI Kang, A Alarcon de la Lastra, NC Borcherding, ...
bioRxiv, 2022.02. 09.479745, 2022
72022
Het systeem kan de bewerking nu niet uitvoeren. Probeer het later opnieuw.
Artikelen 1–20