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Ranjit S. Bindra
Ranjit S. Bindra
Associate Professor, Yale Medical School
Geverifieerd e-mailadres voor yale.edu
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Mutations in the chloride channel gene, CLCNKB, cause Bartter's syndrome type III
DB Simon, RS Bindra, TA Mansfield, C Nelson-Williams, E Mendonca, ...
Nature genetics 17 (2), 171-178, 1997
10161997
Glioblastoma in adults: a Society for Neuro-Oncology (SNO) and European Society of Neuro-Oncology (EANO) consensus review on current management and future directions
PY Wen, M Weller, EQ Lee, BM Alexander, JS Barnholtz-Sloan, ...
Neuro-oncology 22 (8), 1073-1113, 2020
7042020
2-Hydroxyglutarate produced by neomorphic IDH mutations suppresses homologous recombination and induces PARP inhibitor sensitivity
PL Sulkowski, CD Corso, ND Robinson, SE Scanlon, KR Purshouse, ...
Science translational medicine 9 (375), eaal2463, 2017
5072017
Down-regulation of Rad51 and decreased homologous recombination in hypoxic cancer cells
RS Bindra, PJ Schaffer, A Meng, J Woo, K Måseide, ME Roth, P Lizardi, ...
Molecular and cellular biology 24 (19), 8504-8518, 2004
4112004
Hypoxia-induced down-regulation of BRCA1 expression by E2Fs
RS Bindra, SL Gibson, A Meng, U Westermark, M Jasin, AJ Pierce, ...
Cancer research 65 (24), 11597-11604, 2005
3792005
Residual Convolutional Neural Network for the Determination of IDH Status in Low- and High-Grade Gliomas from MR Imaging
K Chang, HX Bai, H Zhou, C Su, WL Bi, E Agbodza, VK Kavouridis, ...
Clinical Cancer Research 24 (5), 1073-1081, 2018
3712018
Chronic hypoxia decreases synthesis of homologous recombination proteins to offset chemoresistance and radioresistance
N Chan, M Koritzinsky, H Zhao, R Bindra, PM Glazer, S Powell, ...
Cancer research 68 (2), 605-614, 2008
3512008
Decreased Expression of the DNA Mismatch Repair Gene Mlh1 under Hypoxic Stress in Mammalian Cells
VT Mihaylova, RS Bindra, J Yuan, D Campisi, L Narayanan, R Jensen, ...
Molecular and cellular biology 23 (9), 3265-3273, 2003
3302003
Inhibition of poly (ADP-ribose) polymerase down-regulates BRCA1 and RAD51 in a pathway mediated by E2F4 and p130
DC Hegan, Y Lu, GC Stachelek, ME Crosby, RS Bindra, PM Glazer
Proceedings of the National Academy of Sciences 107 (5), 2201-2206, 2010
2472010
Regulation of DNA repair in hypoxic cancer cells
RS Bindra, ME Crosby, PM Glazer
Cancer and Metastasis Reviews 26, 249-260, 2007
2412007
Oncometabolites suppress DNA repair by disrupting local chromatin signalling
PL Sulkowski, S Oeck, J Dow, NG Economos, L Mirfakhraie, Y Liu, ...
Nature 582 (7813), 586-591, 2020
2232020
Hypoxia down-regulates DNA double strand break repair gene expression in prostate cancer cells
AX Meng, F Jalali, A Cuddihy, N Chan, RS Bindra, PM Glazer, RG Bristow
Radiotherapy and Oncology 76 (2), 168-176, 2005
2172005
Genetic instability and the tumor microenvironment: towards the concept of microenvironment-induced mutagenesis
RS Bindra, PM Glazer
Mutation Research/Fundamental and Molecular Mechanisms of Mutagenesis 569 (1 …, 2005
2052005
Krebs-cycle-deficient hereditary cancer syndromes are defined by defects in homologous-recombination DNA repair
PL Sulkowski, RK Sundaram, S Oeck, CD Corso, Y Liu, S Noorbakhsh, ...
Nature Genetics 50 (8), 1086-1092, 2018
1832018
Repression of RAD51 gene expression by E2F4/p130 complexes in hypoxia
RS Bindra, PM Glazer
Oncogene 26 (14), 2048-2057, 2007
1772007
Repression of RAD51 gene expression by E2F4/p130 complexes in hypoxia
RS Bindra, PM Glazer
Oncogene 26 (14), 2048-2057, 2007
1772007
Hypoxia-induced genetic instability—a calculated mechanism underlying tumor progression
LE Huang, RS Bindra, PM Glazer, AL Harris
Journal of Molecular Medicine 85, 139-148, 2007
1752007
SAMHD1 promotes DNA end resection to facilitate DNA repair by homologous recombination
W Daddacha, AE Koyen, AJ Bastien, PSE Head, VR Dhere, GN Nabeta, ...
Cell reports 20 (8), 1921-1935, 2017
1692017
VHL-mediated hypoxia regulation of cyclin D1 in renal carcinoma cells
RS Bindra, JR Vasselli, R Stearman, WM Linehan, RD Klausner
Cancer research 62 (11), 3014-3019, 2002
1592002
Pediatric high-grade glioma: current molecular landscape and therapeutic approaches
S Braunstein, D Raleigh, R Bindra, S Mueller, D Haas-Kogan
Journal of neuro-oncology 134, 541-549, 2017
1432017
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