TLR7/8-mediated activation of human NK cells results in accessory cell-dependent IFN-γ production OM Hart, V Athie-Morales, GM O’Connor, CM Gardiner The journal of immunology 175 (3), 1636-1642, 2005 | 402 | 2005 |
Mg2+ regulates cytotoxic functions of NK and CD8 T cells in chronic EBV infection through NKG2D B Chaigne-Delalande, FY Li, GM O’Connor, MJ Lukacs, P Jiang, L Zheng, ... Science 341 (6142), 186-191, 2013 | 367 | 2013 |
HLA-C cell surface expression and control of HIV/AIDS correlate with a variant upstream of HLA-C R Thomas, R Apps, Y Qi, X Gao, V Male, C O'huigin, G O'Connor, D Ge, ... Nature genetics 41 (12), 1290-1294, 2009 | 330 | 2009 |
Lentiviral hematopoietic stem cell gene therapy for X-linked severe combined immunodeficiency SS De Ravin, X Wu, S Moir, L Kardava, S Anaya-O’Brien, N Kwatemaa, ... Science translational medicine 8 (335), 335ra57-335ra57, 2016 | 305 | 2016 |
Putting the natural killer cell in its place GM O'Connor, OM Hart, CM Gardiner Immunology 117 (1), 1-10, 2006 | 218 | 2006 |
Killer cell immunoglobulin-like receptor 3DL1-mediated recognition of human leukocyte antigen B JP Vivian, RC Duncan, R Berry, GM O’Connor, HH Reid, T Beddoe, ... Nature 479 (7373), 401-405, 2011 | 214 | 2011 |
Functional polymorphism of the KIR3DL1/S1 receptor on human NK cells GM O’Connor, KJ Guinan, RT Cunningham, D Middleton, P Parham, ... The Journal of Immunology 178 (1), 235-241, 2007 | 209 | 2007 |
A bird's eye view of NK cell receptor interactions with their MHC class I ligands PM Saunders, JP Vivian, GM O'Connor, LC Sullivan, P Pymm, J Rossjohn, ... Immunological reviews 267 (1), 148-166, 2015 | 111 | 2015 |
Natural Killer cells from long-term non-progressor HIV patients are characterized by altered phenotype and function GM O’Connor, A Holmes, F Mulcahy, CM Gardiner Clinical immunology 124 (3), 277-283, 2007 | 101 | 2007 |
MHC-I peptides get out of the groove and enable a novel mechanism of HIV-1 escape P Pymm, PT Illing, SH Ramarathinam, GM O'Connor, VA Hughes, ... Nature structural & molecular biology 24 (4), 387-394, 2017 | 99 | 2017 |
Killer cell immunoglobulin-like receptor 3DL1 polymorphism defines distinct hierarchies of HLA class I recognition PM Saunders, P Pymm, G Pietra, VA Hughes, C Hitchen, GM O’Connor, ... Journal of Experimental Medicine 213 (5), 791-807, 2016 | 91 | 2016 |
Peptide-dependent recognition of HLA-B* 57: 01 by KIR3DS1 GM O'Connor, JP Vivian, E Gostick, P Pymm, BAP Lafont, DA Price, ... Journal of virology 89 (10), 5213-5221, 2015 | 90 | 2015 |
Common HIV-1 peptide variants mediate differential binding of KIR3DL1 to HLA-Bw4 molecules L Fadda, GM O'Connor, S Kumar, A Piechocka-Trocha, CM Gardiner, ... Journal of virology 85 (12), 5970-5974, 2011 | 83 | 2011 |
Activation of human NK cells by the bacterial pathogen-associated molecular pattern muramyl dipeptide V Athié-Morales, GM O’Connor, CM Gardiner The Journal of Immunology 180 (6), 4082-4089, 2008 | 58 | 2008 |
Mutational and structural analysis of KIR3DL1 reveals a lineage-defining allotypic dimorphism that impacts both HLA and peptide sensitivity GM O’Connor, JP Vivian, JM Widjaja, JS Bridgeman, E Gostick, ... The Journal of Immunology 192 (6), 2875-2884, 2014 | 57 | 2014 |
Interaction of a dengue virus NS1-derived peptide with the inhibitory receptor KIR3DL1 on natural killer cells E Townsley, G O'connor, C Cosgrove, M Woda, M Co, SJ Thomas, ... Clinical & Experimental Immunology 183 (3), 419-430, 2016 | 41 | 2016 |
The yin-yang of KIR3DL1/S1: molecular mechanisms and cellular function GM O'Connor, DW McVicar Critical Reviews™ in Immunology 33 (3), 2013 | 40 | 2013 |
Analysis of binding of KIR3DS1* 014 to HLA suggests distinct evolutionary history of KIR3DS1 GM O’Connor, E Yamada, A Rampersaud, R Thomas, M Carrington, ... The Journal of Immunology 187 (5), 2162-2171, 2011 | 36 | 2011 |
The interaction of KIR3DL1* 001 with HLA class I molecules is dependent upon molecular microarchitecture within the Bw4 epitope PM Saunders, JP Vivian, N Baschuk, T Beddoe, J Widjaja, GM O’Connor, ... The Journal of Immunology 194 (2), 781-789, 2015 | 34 | 2015 |
Pemphigus is associated with KIR3DL2 expression levels and provides evidence that KIR3DL2 may bind HLA-A3 and A11 in vivo. PEML Augusto DG, O'Connor GM, Lobo-Alves SC, Bass S, Martin MP, Carrington M ... European Journal of Immunology, 2015 | 31 | 2015 |