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Zhen-Qiang Pan
Zhen-Qiang Pan
Professor of Oncological Sciences, Icahn School of Medicine at Mount Sinai
Geverifieerd e-mailadres voor mssm.edu
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Identification of ubiquitin ligases required for skeletal muscle atrophy
SC Bodine, E Latres, S Baumhueter, VKM Lai, L Nunez, BA Clarke, ...
Science 294 (5547), 1704-1708, 2001
39712001
Cdk-interacting protein 1 directly binds with proliferating cell nuclear antigen and inhibits DNA replication catalyzed by the DNA polymerase delta holoenzyme.
H Flores-Rozas, Z Kelman, FB Dean, ZQ Pan, JW Harper, SJ Elledge, ...
Proceedings of the National Academy of Sciences 91 (18), 8655-8659, 1994
6051994
The cullin protein family
A Sarikas, T Hartmann, ZQ Pan
Genome biology 12, 1-12, 2011
5502011
Nedd8 on cullin: building an expressway to protein destruction
ZQ Pan, A Kentsis, DC Dias, K Yamoah, K Wu
Oncogene 23 (11), 1985-1997, 2004
4912004
Inhibition of p21‐mediated ROS accumulation can rescue p21‐induced senescence
S Macip, M Igarashi, L Fang, A Chen, ZQ Pan, SW Lee, SA Aaronson
The EMBO journal, 2002
4372002
Recruitment of a ROC1–CUL1 ubiquitin ligase by Skp1 and HOS to catalyze the ubiquitination of IκBα
P Tan, SY Fuchs, A Chen, K Wu, C Gomez, Z Ronai, ZQ Pan
Molecular cell 3 (4), 527-533, 1999
4351999
SUMO-1 modification of Mdm2 prevents its self-ubiquitination and increases Mdm2 ability to ubiquitinate p53
T Buschmann, SY Fuchs, CG Lee, ZQ Pan, Z Ronai
Cell 101 (7), 753-762, 2000
3742000
Commensal bacteria modulate cullin‐dependent signaling via generation of reactive oxygen species
A Kumar, H Wu, LS Collier‐Hyams, JM Hansen, T Li, K Yamoah, ZQ Pan, ...
The EMBO journal 26 (21), 4457-4466, 2007
2972007
Studies on the activator 1 protein complex, an accessory factor for proliferating cell nuclear antigen-dependent DNA polymerase delta.
SH Lee, AD Kwong, ZQ Pan, J Hurwitz
Journal of Biological Chemistry 266 (1), 594-602, 1991
2961991
Autoubiquitination of the BRCA1· BARD1 RING ubiquitin ligase
A Chen, FE Kleiman, JL Manley, T Ouchi, ZQ Pan
Journal of Biological Chemistry 277 (24), 22085-22092, 2002
2902002
Clamp loading, unloading and intrinsic stability of the PCNA, β and gp45 sliding clamps of human, E. coli and T4 replicases
N Yao, J Turner, Z Kelman, PT Stukenberg, F Dean, D Shechter, ZQ Pan, ...
Genes to Cells 1 (1), 101-113, 1996
2721996
The CUL7 E3 ubiquitin ligase targets insulin receptor substrate 1 for ubiquitin-dependent degradation
X Xu, A Sarikas, DC Dias-Santagata, G Dolios, PJ Lafontant, SC Tsai, ...
Molecular cell 30 (4), 403-414, 2008
2582008
Synthesis of DNA by DNA polymerase epsilon in vitro.
SH Lee, ZQ Pan, AD Kwong, PM Burgers, J Hurwitz
Journal of Biological Chemistry 266 (33), 22707-22717, 1991
2561991
p53 Is Phosphorylated by CDK7-Cyclin H in a p36MAT1-Dependent Manner
LJ Ko, SY Shieh, X Chen, L Jayaraman, K Tamai, Y Taya, C Prives, ...
Molecular and cellular biology 17 (12), 7220-7229, 1997
2481997
Conjugation of Nedd8 to CUL1 enhances the ability of the ROC1-CUL1 complex to promote ubiquitin polymerization
K Wu, A Chen, ZQ Pan
Journal of Biological Chemistry 275 (41), 32317-32324, 2000
2452000
HOS, a human homolog of Slimb, forms an SCF complex with Skp1 and Cullin1 and targets the phosphorylation-dependent degradation of IκB and β-catenin
SY Fuchs, A Chen, Y Xiong, ZQ Pan, Z Ronai
Oncogene 18 (12), 2039-2046, 1999
2411999
The Mdm2 RING domain C‐terminus is required for supramolecular assembly and ubiquitin ligase activity
MV Poyurovsky, C Priest, A Kentsis, KLB Borden, ZQ Pan, N Pavletich, ...
The EMBO journal 26 (1), 90-101, 2007
2382007
Inhibition of nucleotide excision repair by the cyclin-dependent kinase inhibitor p21
ZQ Pan, JT Reardon, L Li, H Flores-Rozas, R Legerski, A Sancar, ...
Journal of Biological Chemistry 270 (37), 22008-22016, 1995
2381995
Identification and characterization of DEN1, a deneddylase of the ULP family
T Gan-Erdene, K Nagamalleswari, L Yin, K Wu, ZQ Pan, KD Wilkinson
Journal of Biological Chemistry 278 (31), 28892-28900, 2003
2372003
DEN1 is a dual function protease capable of processing the C terminus of Nedd8 and deconjugating hyper-neddylated CUL1
K Wu, K Yamoah, G Dolios, T Gan-Erdene, P Tan, A Chen, C Lee, N Wei, ...
Journal of Biological Chemistry 278 (31), 28882-28891, 2003
2192003
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