| Metabolism of low-dose inorganic arsenic in a central European population: influence of sex and genetic polymorphisms AL Lindberg, R Kumar, W Goessler, RK Thirumaran, E Gurzau, ... Environmental health perspectives 115 (7), 1081, 2007 | 260 | 2007 |
| Pharmacogenetic Allele Nomenclature: International Workgroup Recommendations for Test Result Reporting. LV Kalman, JAG Agundez, ML Appell, JL Black, GC Bell, S Boukouvala, ... Clinical Pharmacology and Therapeutics, 2015 | 190 | 2015 |
| B-RAF and N-RAS mutations are preserved during short time in vitro propagation and differentially impact prognosis S Ugurel, RK Thirumaran, S Bloethner, A Gast, A Sucker, ... PloS one 2 (2), e236, 2007 | 168 | 2007 |
| Clinical impact of pharmacogenetic profiling with a clinical decision support tool in polypharmacy home health patients: a prospective pilot randomized controlled trial LS Elliott, JC Henderson, MB Neradilek, NA Moyer, KC Ashcraft, ... PloS one 12 (2), e0170905, 2017 | 160 | 2017 |
| Identification of CYP1A2 as the main isoform for the phase I hydroxylated metabolism of genistein and a prodrug converting enzyme of methylated isoflavones M Hu, K Krausz, J Chen, X Ge, J Li, HL Gelboin, FJ Gonzalez Drug Metabolism and Disposition 31 (7), 924-931, 2003 | 139 | 2003 |
| Drug transporters on arachnoid barrier cells contribute to the blood cerebrospinal fluid barrier K Yasuda, C Cline, P Vogel, M Onciu, S Fatima, BP Sorrentino, ... Drug Metabolism and Disposition 41 (4), 923-931, 2013 | 132 | 2013 |
| Polymorphisms in the DNA repair genes XRCC1, APEX1, XRCC3 and NBS1, and the risk for lung cancer in never and ever smokers C Ryk, R Kumar, RK Thirumaran, SM Hou Lung cancer 54 (3), 285-292, 2006 | 128 | 2006 |
| Single nucleotide polymorphisms in DNA repair genes and basal cell carcinoma of skin RK Thirumaran, JL Bermejo, P Rudnai, E Gurzau, K Koppova, W Goessler, ... Carcinogenesis 27 (8), 1676-1681, 2006 | 102 | 2006 |
| Melanocortin receptor 1 variants and melanoma risk: a study of 2 European populations D Scherer, E Nagore, JL Bermejo, A Figl, R Botella‐Estrada, ... International journal of cancer 125 (8), 1868-1875, 2009 | 85 | 2009 |
| Determination of allele frequency in pooled DNA: comparison of three PCR based methods. S Wilkening, K Hemminki, RK Thirumaran, JL Bermejo, S Bonn, A Försti, ... Biotechniques 39 (6), 853-858, 2005 | 82 | 2005 |
| MTHFR genetic polymorphisms and susceptibility to childhood acute lymphoblastic leukemia RK Thirumaran, A Gast, T Flohr, B Burwinkel, C Bartram, K Hemminki, ... Blood 106 (7), 2590-2591, 2005 | 62 | 2005 |
| Intestinal CYP3A4 and Midazolam disposition in vivo associate with VDR polymorphisms and show seasonal variation. SEG Thirumaran RK, Lamba JK, Kim RB, Urquhart BL Biochemical Pharmacology 1 (84 (1)), 104-12, 2012 | 60* | 2012 |
| Cytochrome P–450 gene and drug interaction analysis in patients referred for pharmacogenetic testing BT Hocum, JR White Jr, JW Heck, RK Thirumaran, N Moyer, R Newman, ... American Journal of Health-System Pharmacy 73 (2), 61-67, 2016 | 58 | 2016 |
| Exploration of CYP450 and drug transporter genotypes and correlations with nevirapine exposure in Malawians KC Brown, MC Hosseinipour, JM Hoskins, RK Thirumaran, HC Tien, ... Pharmacogenomics, 1-9, 2011 | 48 | 2011 |
| Multisite phosphorylation of human liver cytochrome P450 3A4 enhances its gp78-and CHIP-mediated ubiquitination: A pivotal role of its S478 residue in the gp78-catalyzed reaction. Y Wang, S Guan, P Acharya, RK Thirumaran, Y Liu, R Brandman, ... Molecular & cellular proteomics: MCP, 2011 | 37 | 2011 |
| The influence of sex, ethnicity, and CYP2B6 genotype on Bupropion metabolism as an index of hepatic CYP2B6 activity in humans K Ilic, RL Hawke, RK Thirumaran, EG Schuetz, JH Hull, ADM Kashuba, ... Drug Metabolism and Disposition 41 (3), 575-581, 2013 | 36 | 2013 |
| Single nucleotide polymorphisms in DNA-repair genes and cutaneous melanoma A Figl, D Scherer, E Nagore, JL Bermejo, R Estrada, A Gast, ... Mutation Research/Genetic Toxicology and Environmental Mutagenesis 702 (1), 8-16, 2010 | 36 | 2010 |
| Single nucleotide polymorphisms in DNA repair genes XRCC1 and APEX1 in progression and survival of primary cutaneous melanoma patients A Figl, D Scherer, E Nagore, JL Bermejo, E Dickes, RK Thirumaran, ... Mutation Research/Fundamental and Molecular Mechanisms of Mutagenesis 661 (1 …, 2009 | 33 | 2009 |
| Genetic variation in aldo-keto reductase 1D1 affects the expression and activity of multiple cytochrome P450s AS Chaudhry, RK Thirumaran, K Yasuda, X Yang, Y Fan, SC Strom, ... Drug Metabolism and Disposition 41 (8), 1538-1547, 2013 | 28 | 2013 |
| Prediction of CYP3A4 enzyme activity using haplotype tag SNPs in African Americans MA Perera, RK Thirumaran, NJ Cox, S Hanauer, S Das, C Brimer-Cline, ... The pharmacogenomics journal 9 (1), 49-60, 2009 | 27 | 2009 |
Giovanni LeonardiHonorary Associate Professor, London School of Hygiene and Tropical MedicineGeverifieerd e-mailadres voor lshtm.ac.uk
