c-Jun overexpression in CAR T cells induces exhaustion resistance RC Lynn, EW Weber, E Sotillo, D Gennert, P Xu, Z Good, H Anbunathan, ... Nature 576 (7786), 293-300, 2019 | 562 | 2019 |
Transient rest restores functionality in exhausted CAR-T cells through epigenetic remodeling EW Weber, KR Parker, E Sotillo, RC Lynn, H Anbunathan, J Lattin, ... Science 372 (6537), eaba1786, 2021 | 350 | 2021 |
Tuning the antigen density requirement for CAR T-cell activity RG Majzner, SP Rietberg, E Sotillo, R Dong, VT Vachharajani, ... Cancer discovery 10 (5), 702-723, 2020 | 346 | 2020 |
The emerging landscape of immune cell therapies EW Weber, MV Maus, CL Mackall Cell 181 (1), 46-62, 2020 | 327 | 2020 |
Pharmacologic control of CAR-T cell function using dasatinib EW Weber, RC Lynn, E Sotillo, J Lattin, P Xu, CL Mackall Blood advances 3 (5), 711-717, 2019 | 180 | 2019 |
TRPC6 is the endothelial calcium channel that regulates leukocyte transendothelial migration during the inflammatory response EW Weber, F Han, M Tauseef, L Birnbaumer, D Mehta, WA Muller Journal of Experimental Medicine 212 (11), 1883-1899, 2015 | 120 | 2015 |
Enhanced safety and efficacy of protease-regulated CAR-T cell receptors L Labanieh, RG Majzner, D Klysz, E Sotillo, CJ Fisher, JG Vilches-Moure, ... Cell 185 (10), 1745-1763. e22, 2022 | 103 | 2022 |
Co-opting signalling molecules enables logic-gated control of CAR T cells AM Tousley, MC Rotiroti, L Labanieh, LW Rysavy, WJ Kim, C Lareau, ... Nature 615 (7952), 507-516, 2023 | 76 | 2023 |
Enhanced T cell effector activity by targeting the Mediator kinase module KA Freitas, JA Belk, E Sotillo, PJ Quinn, MC Ramello, M Malipatlolla, ... Science 378 (6620), eabn5647, 2022 | 46 | 2022 |
Cyclin‐dependent kinase inhibitor p21, via its C‐terminal domain, is essential for resolution of murine inflammatory arthritis M Mavers, CM Cuda, AV Misharin, AK Gierut, H Agrawal, E Weber, ... Arthritis & Rheumatism 64 (1), 141-152, 2012 | 44 | 2012 |
Dynamic chromatin regulatory landscape of human CAR T cell exhaustion DG Gennert, RC Lynn, JM Granja, EW Weber, MR Mumbach, Y Zhao, ... Proceedings of the National Academy of Sciences 118 (30), e2104758118, 2021 | 42 | 2021 |
Requirement of myeloid cell–specific Fas expression for prevention of systemic autoimmunity in mice CM Cuda, H Agrawal, AV Misharin, GK Haines III, J Hutcheson, E Weber, ... Arthritis & Rheumatism 64 (3), 808-820, 2012 | 26 | 2012 |
Transient rest restores functionality in exhausted CAR-T cells through epigenetic remodeling. Science 372, eaba1786 EW Weber, KR Parker, E Sotillo, RC Lynn, H Anbunathan, J Lattin, ... | 25 | 2021 |
Neurotoxicity associated with a high-affinity GD2 CAR RG Majzner, EW Weber, RC Lynn, P Xu, CL Mackall Cancer immunology research 6 (4), 494-495, 2018 | 23 | 2018 |
Cutting Edge: CD99 Is a Novel Therapeutic Target for Control of T Cell–Mediated Central Nervous System Autoimmune Disease RC Winger, CT Harp, MY Chiang, DP Sullivan, RL Watson, EW Weber, ... The Journal of Immunology 196 (4), 1443-1448, 2016 | 23 | 2016 |
Spatiotemporal restriction of endothelial cell calcium signaling is required during leukocyte transmigration PJ Dalal, DP Sullivan, EW Weber, DB Sacks, M Gunzer, IM Grumbach, ... Journal of Experimental Medicine 218 (1), 2021 | 21 | 2021 |
Transient “rest” induces functional reinvigoration and epigenetic remodeling in exhausted CAR-T cells EW Weber, RC Lynn, KR Parker, H Anbunathan, J Lattin, E Sotillo, ... Biorxiv, 2020.01. 26.920496, 2020 | 19 | 2020 |
BRCA testing in women with high-grade serous ovarian cancer: gynecologic oncologist-initiated testing compared with genetics referral S Piedimonte, J Power, WD Foulkes, E Weber, L Palma, A Schiavi, ... International Journal of Gynecologic Cancer 30 (11), 2020 | 17 | 2020 |
Tonic-signaling chimeric antigen receptors drive human regulatory T cell exhaustion C Lamarche, K Ward-Hartstonge, T Mi, DTS Lin, Q Huang, A Brown, ... Proceedings of the National Academy of Sciences 120 (14), e2219086120, 2023 | 14 | 2023 |
Blocking monocyte transmigration in in vitro system by a human antibody scFv anti-CD99. Efficient large scale purification from periplasmic inclusion bodies in E. coli … D Moricoli, WA Muller, DC Carbonella, MC Balducci, S Dominici, ... Journal of immunological methods 408, 35-45, 2014 | 14 | 2014 |