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Evan W. Weber
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c-Jun overexpression in CAR T cells induces exhaustion resistance
RC Lynn, EW Weber, E Sotillo, D Gennert, P Xu, Z Good, H Anbunathan, ...
Nature 576 (7786), 293-300, 2019
5622019
Transient rest restores functionality in exhausted CAR-T cells through epigenetic remodeling
EW Weber, KR Parker, E Sotillo, RC Lynn, H Anbunathan, J Lattin, ...
Science 372 (6537), eaba1786, 2021
3502021
Tuning the antigen density requirement for CAR T-cell activity
RG Majzner, SP Rietberg, E Sotillo, R Dong, VT Vachharajani, ...
Cancer discovery 10 (5), 702-723, 2020
3462020
The emerging landscape of immune cell therapies
EW Weber, MV Maus, CL Mackall
Cell 181 (1), 46-62, 2020
3272020
Pharmacologic control of CAR-T cell function using dasatinib
EW Weber, RC Lynn, E Sotillo, J Lattin, P Xu, CL Mackall
Blood advances 3 (5), 711-717, 2019
1802019
TRPC6 is the endothelial calcium channel that regulates leukocyte transendothelial migration during the inflammatory response
EW Weber, F Han, M Tauseef, L Birnbaumer, D Mehta, WA Muller
Journal of Experimental Medicine 212 (11), 1883-1899, 2015
1202015
Enhanced safety and efficacy of protease-regulated CAR-T cell receptors
L Labanieh, RG Majzner, D Klysz, E Sotillo, CJ Fisher, JG Vilches-Moure, ...
Cell 185 (10), 1745-1763. e22, 2022
1032022
Co-opting signalling molecules enables logic-gated control of CAR T cells
AM Tousley, MC Rotiroti, L Labanieh, LW Rysavy, WJ Kim, C Lareau, ...
Nature 615 (7952), 507-516, 2023
762023
Enhanced T cell effector activity by targeting the Mediator kinase module
KA Freitas, JA Belk, E Sotillo, PJ Quinn, MC Ramello, M Malipatlolla, ...
Science 378 (6620), eabn5647, 2022
462022
Cyclin‐dependent kinase inhibitor p21, via its C‐terminal domain, is essential for resolution of murine inflammatory arthritis
M Mavers, CM Cuda, AV Misharin, AK Gierut, H Agrawal, E Weber, ...
Arthritis & Rheumatism 64 (1), 141-152, 2012
442012
Dynamic chromatin regulatory landscape of human CAR T cell exhaustion
DG Gennert, RC Lynn, JM Granja, EW Weber, MR Mumbach, Y Zhao, ...
Proceedings of the National Academy of Sciences 118 (30), e2104758118, 2021
422021
Requirement of myeloid cell–specific Fas expression for prevention of systemic autoimmunity in mice
CM Cuda, H Agrawal, AV Misharin, GK Haines III, J Hutcheson, E Weber, ...
Arthritis & Rheumatism 64 (3), 808-820, 2012
262012
Transient rest restores functionality in exhausted CAR-T cells through epigenetic remodeling. Science 372, eaba1786
EW Weber, KR Parker, E Sotillo, RC Lynn, H Anbunathan, J Lattin, ...
252021
Neurotoxicity associated with a high-affinity GD2 CAR
RG Majzner, EW Weber, RC Lynn, P Xu, CL Mackall
Cancer immunology research 6 (4), 494-495, 2018
232018
Cutting Edge: CD99 Is a Novel Therapeutic Target for Control of T Cell–Mediated Central Nervous System Autoimmune Disease
RC Winger, CT Harp, MY Chiang, DP Sullivan, RL Watson, EW Weber, ...
The Journal of Immunology 196 (4), 1443-1448, 2016
232016
Spatiotemporal restriction of endothelial cell calcium signaling is required during leukocyte transmigration
PJ Dalal, DP Sullivan, EW Weber, DB Sacks, M Gunzer, IM Grumbach, ...
Journal of Experimental Medicine 218 (1), 2021
212021
Transient “rest” induces functional reinvigoration and epigenetic remodeling in exhausted CAR-T cells
EW Weber, RC Lynn, KR Parker, H Anbunathan, J Lattin, E Sotillo, ...
Biorxiv, 2020.01. 26.920496, 2020
192020
BRCA testing in women with high-grade serous ovarian cancer: gynecologic oncologist-initiated testing compared with genetics referral
S Piedimonte, J Power, WD Foulkes, E Weber, L Palma, A Schiavi, ...
International Journal of Gynecologic Cancer 30 (11), 2020
172020
Tonic-signaling chimeric antigen receptors drive human regulatory T cell exhaustion
C Lamarche, K Ward-Hartstonge, T Mi, DTS Lin, Q Huang, A Brown, ...
Proceedings of the National Academy of Sciences 120 (14), e2219086120, 2023
142023
Blocking monocyte transmigration in in vitro system by a human antibody scFv anti-CD99. Efficient large scale purification from periplasmic inclusion bodies in E. coli …
D Moricoli, WA Muller, DC Carbonella, MC Balducci, S Dominici, ...
Journal of immunological methods 408, 35-45, 2014
142014
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Artikelen 1–20