| Pten is essential for embryonic development and tumour suppression A Di Cristofano, B Pesce, C Cordon-Cardo, PP Pandolfi Nature Genetics 19 (4), 348-355, 2008 | 1962* | 2008 |
| The multiple roles of PTEN in tumor suppression A Di Cristofano, PP Pandolfi Cell 100 (4), 387-390, 2000 | 1565 | 2000 |
| Crystal structure of the PTEN tumor suppressor: implications for its phosphoinositide phosphatase activity and membrane association JO Lee, H Yang, MM Georgescu, A Di Cristofano, T Maehama, Y Shi, ... Cell 99 (3), 323-334, 1999 | 1361 | 1999 |
| Activation of AKT kinases in cancer: implications for therapeutic targeting A Bellacosa, CC Kumar, A Di Cristofano, JR Testa Advances in cancer research 94, 29-86, 2005 | 1019 | 2005 |
| Sox2 deficiency causes neurodegeneration and impaired neurogenesis in the adult mouse brain ALM Ferri, M Cavallaro, D Braida, A Di Cristofano, A Canta, A Vezzani, ... Oxford University Press for The Company of Biologists Limited 131 (15), 3805 …, 2004 | 842 | 2004 |
| Pten dose dictates cancer progression in the prostate LC Trotman, M Niki, ZA Dotan, JA Koutcher, A Di Cristofano, A Xiao, ... PLoS biology 1 (3), e59, 2003 | 834 | 2003 |
| Impaired Fas Response and Autoimmunity in Pten+/− Mice AD Cristofano, P Kotsi, YF Peng, C Cordon-Cardo, KB Elkon, PP Pandolfi Science 285 (5436), 2122-2125, 1999 | 684 | 1999 |
| Pten and p27KIP1 cooperate in prostate cancer tumor suppression in the mouse A Di Cristofano, M De Acetis, A Koff, C Cordon-Cardo, P P Pandolfi Nature genetics 27 (2), 222-224, 2001 | 615 | 2001 |
| 2021 American thyroid association guidelines for management of patients with anaplastic thyroid cancer: American thyroid association anaplastic thyroid cancer guidelines task force KC Bible, E Kebebew, J Brierley, JP Brito, ME Cabanillas, TJ Clark Jr, ... Thyroid 31 (3), 337-386, 2021 | 395 | 2021 |
| Activation of Akt/Protein Kinase B Overcomes a G2/M Cell Cycle Checkpoint Induced by DNA Damage ES Kandel, J Skeen, N Majewski, A Di Cristofano, PP Pandolfi, ... Molecular and cellular biology 22 (22), 7831-7841, 2002 | 393 | 2002 |
| The deficiency of Akt1 is sufficient to suppress tumor development in Pten+/− mice ML Chen, PZ Xu, X Peng, WS Chen, G Guzman, X Yang, A Di Cristofano, ... Genes & development 20 (12), 1569-1574, 2006 | 317 | 2006 |
| Endometrial carcinoma A Di Cristofano, LH Ellenson Annu. Rev. Pathol. Mech. Dis. 2, 57-85, 2007 | 279 | 2007 |
| Positive feedback regulation between AKT activation and fatty acid synthase expression in ovarian carcinoma cells HQ Wang, DA Altomare, KL Skele, PI Poulikakos, FP Kuhajda, ... Oncogene 24 (22), 3574-3582, 2005 | 237 | 2005 |
| The ETS protein MEF plays a critical role in perforin gene expression and the development of natural killer and NK-T cells HD Lacorazza, Y Miyazaki, A Di Cristofano, A Deblasio, C Hedvat, ... Immunity 17 (4), 437-449, 2002 | 234 | 2002 |
| PTEN and TNF-α regulation of the intestinal-specific Cdx-2 homeobox gene through a PI3K, PKB/Akt, and NF-κB–dependent pathway S Kim, C Domon-Dell, Q Wang, DH Chung, A Di Cristofano, PP Pandolfi, ... Gastroenterology 123 (4), 1163-1178, 2002 | 174 | 2002 |
| PTEN in neural precursor cells: regulation of migration, apoptosis, and proliferation L Li, F Liu, RA Salmonsen, TK Turner, NS Litofsky, A Di Cristofano, ... Molecular and cellular neuroscience 20 (1), 21-29, 2002 | 168 | 2002 |
| Molecular cloning and characterization of p56dok-2 defines a new family of RasGAP-binding proteins A Di Cristofano, N Carpino, N Dunant, G Friedland, R Kobayashi, A Strife, ... Journal of Biological Chemistry 273 (9), 4827-4830, 1998 | 167 | 1998 |
| Oncogenic Kras requires simultaneous PI3K signaling to induce ERK activation and transform thyroid epithelial cells in vivo KA Miller, N Yeager, K Baker, XH Liao, S Refetoff, A Di Cristofano Cancer research 69 (8), 3689-3694, 2009 | 154 | 2009 |
| Pten loss in the mouse thyroid causes goiter and follicular adenomas: insights into thyroid function and Cowden disease pathogenesis N Yeager, A Klein-Szanto, S Kimura, A Di Cristofano Cancer research 67 (3), 959-966, 2007 | 146 | 2007 |
| Class reunion: PTEN joins the nuclear crew Z Lian, A Di Cristofano Oncogene 24 (50), 7394-7400, 2005 | 144 | 2005 |
