Ole Thastrup
Ole Thastrup
Verified email at sund.ku.dk
TitleCited byYear
Thapsigargin, a tumor promoter, discharges intracellular Ca2+ stores by specific inhibition of the endoplasmic reticulum Ca2 (+)-ATPase
O Thastrup, PJ Cullen, BK Drøbak, MR Hanley, AP Dawson
Proceedings of the National Academy of Sciences 87 (7), 2466-2470, 1990
33141990
Activation of calcium entry by the tumor promoter thapsigargin in parotid acinar cells. Evidence that an intracellular calcium pool and not an inositol phosphate regulates …
H Takemura, AR Hughes, O Thastrup, JW Putney
Journal of Biological Chemistry 264 (21), 12266-12271, 1989
8211989
Thapsigargin, a novel molecular probe for studying intracellular calcium release and storage
O Thastrup, AP Dawson, O Scharff, B Foder, PJ Cullen, BK Drøbak, ...
Agents and actions 27 (1-2), 17-23, 1989
590*1989
[Leu31, Pro34] neuropeptide Y: a specific Y1 receptor agonist
J Fuhlendorff, U Gether, L Aakerlund, N Langeland-Johansen, ...
Proceedings of the National Academy of Sciences 87 (1), 182-186, 1990
4321990
A novel tumour promoter, thapsigargin, transiently increases cytoplasmic free Ca2+ without generation of inositol phosphates in NG115-401L neuronal cells
TR Jackson, SI Patterson, O Thastrup, MR Hanley
Biochemical Journal 253 (1), 81-86, 1988
3231988
Role of Ca2+-ATPases in regulation of cellular Ca2+ signalling, as studied with the selective microsomal Ca2+-ATPase inhibitor, thapsigargin
O Thastrup
Agents and actions 29 (1-2), 8-15, 1990
2671990
Separation of the glucose-stimulated cytoplasmic and mitochondrial NAD (P) H responses in pancreatic islet β cells
GH Patterson, SM Knobel, P Arkhammar, O Thastrup, DW Piston
Proceedings of the National Academy of Sciences 97 (10), 5203-5207, 2000
2662000
Effects of MeCh, thapsigargin, and La3+ on plasmalemmal and intracellular Ca2+ transport in lacrimal acinar cells
CY Kwan, H Takemura, JF Obie, O Thastrup, JW Putney Jr
American Journal of Physiology-Cell Physiology 258 (6), C1006-C1015, 1990
2011990
Signal transduction via the mitogen-activated protein kinase pathway induced by binding of coagulation factor VIIa to tissue factor
LK Poulsen, N Jacobsen, BB Sørensen, NCH Bergenhem, JD Kelly, ...
Journal of Biological Chemistry 273 (11), 6228-6232, 1998
1881998
How do inositol phosphates regulate calcium signaling?
JW Putney Jr, H Takemura, AR Hughes, DA Horstman, O Thastrup
The FASEB journal 3 (8), 1899-1905, 1989
1731989
Y1 receptors for neuropeptide Y are coupled to mobilization of intracellular calcium and inhibition of adenylate cyclase
L Aakerlund, U Gether, J Fuhlendorff, TW Schwartz, O Thastrup
FEBS letters 260 (1), 73-78, 1990
1681990
Jr Activation of calcium entry by the tumor promoter thapsigargin in parotid acinar cells. Evidence that an intracellular calcium pool and not an inositol phosphate regulates …
H Takemura, AR Hughes, O Thastrup, JW Putney Jr
J Biol Chem 264 (21), 12266-12271, 1989
1601989
Demonstration of two forms of calcium pumps by thapsigargin inhibition and radioimmunoblotting in platelet membrane vesicles.
B Papp, A Enyedi, T Kovács, B Sarkadi, F Wuytack, O Thastrup, G Gárdos, ...
Journal of Biological Chemistry 266 (22), 14593-14596, 1991
1401991
The calcium mobilizing and tumor promoting agent, thapsigargin elevates the platelet cytoplasmic free calcium concentration to a higher steady state level. A possible mechanism …
O Thastrup, B Foder, O Scharff
Biochemical and biophysical research communications 142 (3), 654-660, 1987
1401987
Method of detecting biologically active substances by using green fluorescent protein
O Thastrup, LK Poulsen
US Patent 5,958,713, 1999
1121999
The ability of thapsigargin and thapsigargicin to activate cells involved in the inflammatory response
H Ali, SB Christensen, JC Foreman, FL Pearce, W Piotrowski, O Thastrup
British journal of pharmacology 85 (3), 705-712, 1985
1101985
Fluorescent proteins
O Thastrup, S Tullin, LK Poulsen, SP Bjørn
US Patent 6,172,188, 2001
1032001
Method and apparatus for high density format screening for bioactive molecules
BR Terry, KM Scudder, POG Arkhammer, O Thastrup
US Patent 6,790,652, 2004
942004
The inflammatory and tumor-promoting sesquiterpene lactone, thapsigargin, activates platelets by selective mobilization of calcium as shown by protein phosphorylations
O Thastrup, H Linnebjerg, PJ Bjerrum, JB Knudsen, SB Christensen
Biochimica et Biophysica Acta (BBA)-Molecular Cell Research 927 (1), 65-73, 1987
941987
Inositol trisphosphate and thapsigargin discriminate endoplasmic reticulum stores of calcium in rat brain
A Verma, DJ Hirsch, MR Hanley, O Thastrup, SB Christensen, SH Snyder
Biochemical and biophysical research communications 172 (2), 811-816, 1990
801990
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