| SARS-CoV-2 reverse genetics reveals a variable infection gradient in the respiratory tract YJ Hou, K Okuda, CE Edwards, DR Martinez, T Asakura, KH Dinnon, ... Cell 182 (2), 429-446. e14, 2020 | 1460 | 2020 |
| Administration of vorinostat disrupts HIV-1 latency in patients on antiretroviral therapy NM Archin, AL Liberty, AD Kashuba, SK Choudhary, JD Kuruc, ... Nature 487 (7408), 482-485, 2012 | 1334 | 2012 |
| The challenge of finding a cure for HIV infection DD Richman, DM Margolis, M Delaney, WC Greene, D Hazuda, ... Science 323 (5919), 1304-1307, 2009 | 1071 | 2009 |
| SARS-CoV-2 D614G variant exhibits efficient replication ex vivo and transmission in vivo YJ Hou, S Chiba, P Halfmann, C Ehre, M Kuroda, KH Dinnon III, SR Leist, ... Science 370 (6523), 1464-1468, 2020 | 897 | 2020 |
| The receptor-binding domain of the viral spike protein is an immunodominant and highly specific target of antibodies in SARS-CoV-2 patients L Premkumar, B Segovia-Chumbez, R Jadi, DR Martinez, R Raut, ... Science immunology 5 (48), eabc8413, 2020 | 872 | 2020 |
| Depletion of latent HIV-1 infection in vivo: a proof-of-concept study G Lehrman, IB Hogue, S Palmer, C Jennings, CA Spina, A Wiegand, ... The Lancet 366 (9485), 549-555, 2005 | 682 | 2005 |
| Towards an HIV cure: a global scientific strategy Nature reviews Immunology 12 (8), 607-614, 2012 | 605 | 2012 |
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| Inhibition of HIV fusion with multivalent gold nanoparticles MC Bowman, TE Ballard, CJ Ackerson, DL Feldheim, DM Margolis, ... Journal of the American Chemical Society 130 (22), 6896-6897, 2008 | 454 | 2008 |
| An in-depth comparison of latent HIV-1 reactivation in multiple cell model systems and resting CD4+ T cells from aviremic patients CA Spina, J Anderson, NM Archin, A Bosque, J Chan, M Famiglietti, ... PLoS pathogens 9 (12), e1003834, 2013 | 447 | 2013 |
| The human factors YY1 and LSF repress the human immunodeficiency virus type 1 long terminal repeat via recruitment of histone deacetylase 1 JJ Coull, F Romerio, JM Sun, JL Volker, KM Galvin, JR Davie, Y Shi, ... Journal of virology 74 (15), 6790-6799, 2000 | 435 | 2000 |
| Precise quantitation of the latent HIV-1 reservoir: implications for eradication strategies AM Crooks, R Bateson, AB Cope, NP Dahl, MK Griggs, JAD Kuruc, ... The Journal of infectious diseases 212 (9), 1361-1365, 2015 | 427 | 2015 |
| Expression of latent HIV induced by the potent HDAC inhibitor suberoylanilide hydroxamic acid NM Archin, A Espeseth, D Parker, M Cheema, D Hazuda, DM Margolis AIDS research and human retroviruses 25 (2), 207-212, 2009 | 425 | 2009 |
| The effect of raltegravir intensification on low-level residual viremia in HIV-infected patients on antiretroviral therapy: a randomized controlled trial RT Gandhi, L Zheng, RJ Bosch, ES Chan, DM Margolis, S Read, ... PLoS medicine 7 (8), e1000321, 2010 | 356 | 2010 |
| Eradicating HIV-1 infection: seeking to clear a persistent pathogen NM Archin, JM Sung, C Garrido, N Soriano-Sarabia, DM Margolis Nature Reviews Microbiology 12 (11), 750-764, 2014 | 351 | 2014 |
| BET bromodomain inhibition as a novel strategy for reactivation of HIV-1 C Banerjee, N Archin, D Michaels, AC Belkina, GV Denis, J Bradner, ... Journal of leukocyte biology 92 (6), 1147-1154, 2012 | 343 | 2012 |
| HIV reservoirs: what, where and how to target them MJ Churchill, SG Deeks, DM Margolis, RF Siliciano, R Swanstrom Nature Reviews Microbiology 14 (1), 55-60, 2016 | 320 | 2016 |
| Epigenetic silencing of HIV-1 by the histone H3 lysine 27 methyltransferase enhancer of Zeste 2 J Friedman, WK Cho, CK Chu, KS Keedy, NM Archin, DM Margolis, J Karn Journal of virology 85 (17), 9078-9089, 2011 | 318 | 2011 |
| Coaxing HIV-1 from resting CD4 T cells: histone deacetylase inhibition allows latent viral expression L Ylisastigui, NM Archin, G Lehrman, RJ Bosch, DM Margolis Aids 18 (8), 1101-1108, 2004 | 316 | 2004 |
| Counterregulation of chromatin deacetylation and histone deacetylase occupancy at the integrated promoter of human immunodeficiency virus type 1 (HIV-1) by the HIV-1 repressor … G He, DM Margolis Molecular and cellular biology 22 (9), 2965-2973, 2002 | 306 | 2002 |
Joseph J EronProfessor of Medicine, University of North Carolina at Chapel HillVerified email at med.unc.edu
