Gain of function of mutant p53 by coaggregation with multiple tumor suppressors J Xu, J Reumers, JR Couceiro, F De Smet, R Gallardo, S Rudyak, ... Nature chemical biology 7 (5), 285-295, 2011 | 566 | 2011 |
Roles of PD-1/PD-L1 pathway: signaling, cancer, and beyond L Ai, A Xu, J Xu Regulation of Cancer Immune Checkpoints: Molecular and Cellular Mechanisms …, 2020 | 315 | 2020 |
Inhibiting PD-L1 palmitoylation enhances T-cell immune responses against tumours H Yao, J Lan, C Li, H Shi, JP Brosseau, H Wang, H Lu, C Fang, Y Zhang, ... Nature biomedical engineering 3 (4), 306-317, 2019 | 309 | 2019 |
Long noncoding RNA GAPLINC regulates CD44-dependent cell invasiveness and associates with poor prognosis of gastric cancer Y Hu, J Wang, J Qian, X Kong, J Tang, Y Wang, H Chen, J Hong, W Zou, ... Cancer research 74 (23), 6890-6902, 2014 | 283 | 2014 |
Regulation of PD-L1: emerging routes for targeting tumor immune evasion Y Wang, H Wang, H Yao, C Li, JY Fang, J Xu Frontiers in pharmacology 9, 536, 2018 | 217 | 2018 |
HIP1R targets PD-L1 to lysosomal degradation to alter T cell–mediated cytotoxicity H Wang, H Yao, C Li, H Shi, J Lan, Z Li, Y Zhang, L Liang, JY Fang, J Xu Nature chemical biology 15 (1), 42-50, 2019 | 211 | 2019 |
Cancer cell-intrinsic PD-1 and implications in combinatorial immunotherapy H Yao, H Wang, C Li, JY Fang, J Xu Frontiers in immunology 9, 1774, 2018 | 154 | 2018 |
Gastric cancer and gene copy number variation: emerging cancer drivers for targeted therapy L Liang, JY Fang, J Xu Oncogene 35 (12), 1475-1482, 2016 | 149 | 2016 |
Fecal Clostridium symbiosum for noninvasive detection of early and advanced colorectal cancer: test and validation studies YH Xie, QY Gao, GX Cai, XM Sun, TH Zou, HM Chen, SY Yu, YW Qiu, ... EBioMedicine 25, 32-40, 2017 | 142 | 2017 |
Molecular and cellular functions of CTLA-4 S Van Coillie, B Wiernicki, J Xu Regulation of Cancer Immune Checkpoints: Molecular and Cellular Mechanisms …, 2020 | 135 | 2020 |
Unequal prognostic potentials of p53 gain-of-function mutations in human cancers associate with drug-metabolizing activity J Xu, J Wang, Y Hu, J Qian, B Xu, H Chen, W Zou, JY Fang Cell death & disease 5 (3), e1108-e1108, 2014 | 115 | 2014 |
Long noncoding RNA MEG3 suppresses liver cancer cells growth through inhibiting β-catenin by activating PKM2 and inactivating PTEN Q Zheng, Z Lin, J Xu, Y Lu, Q Meng, C Wang, Y Yang, X Xin, X Li, H Pu, ... Cell death & disease 9 (3), 253, 2018 | 104 | 2018 |
Somatic gene copy number alterations in colorectal cancer: new quest for cancer drivers and biomarkers JX Huanbin Wang, Lunxi Liang, Jing-Yuan Fang Oncogene, onc.2015.304, 2015 | 100* | 2015 |
Rise of PD‐L1 expression during metastasis of colorectal cancer: Implications for immunotherapy HB Wang, H Yao, CS Li, LX Liang, Y Zhang, YX Chen, JY Fang, J Xu Journal of digestive diseases 18 (10), 574-581, 2017 | 93 | 2017 |
Clinical and molecular characterization of Wilson's disease in China: identification of 14 novel mutations XH Li, Y Lu, Y Ling, QC Fu, J Xu, GQ Zang, F Zhou, Y De-Min, Y Han, ... BMC medical genetics 12, 1-13, 2011 | 93 | 2011 |
Elf3 drives β-catenin transactivation and associates with poor prognosis in colorectal cancer JL Wang, ZF Chen, HM Chen, MY Wang, X Kong, YC Wang, TT Sun, ... Cell death & disease 5 (5), e1263, 2014 | 89 | 2014 |
Long noncoding RNA expression profiles in gut tissues constitute molecular signatures that reflect the types of microbes JX Lunxi Liang, Luoyan Ai, Jin Qian, Jing-Yuan Fang Scientific Reports 5, 2015 | 82 | 2015 |
PD-L2 expression in colorectal cancer: Independent prognostic effect and targetability by deglycosylation H Wang, H Yao, C Li, L Liang, Y Zhang, H Shi, C Zhou, Y Chen, JY Fang, ... Oncoimmunology 6 (7), e1327494, 2017 | 76 | 2017 |
OCT1 is a determinant of synbindin-related ERK signalling with independent prognostic significance in gastric cancer J Qian, X Kong, N Deng, P Tan, H Chen, J Wang, Z Li, Y Hu, W Zou, J Xu, ... Gut 64 (1), 37-48, 2015 | 74 | 2015 |
RhoGAPs attenuate cell proliferation by direct interaction with p53 tetramerization domain J Xu, X Zhou, J Wang, Z Li, X Kong, J Qian, Y Hu, JY Fang Cell reports 3 (5), 1526-1538, 2013 | 72 | 2013 |