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Luke Norton
Luke Norton
Associate Professor, University of Texas Health Science Center at San Antonio
Geverifieerd e-mailadres voor uthscsa.edu
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Dapagliflozin improves muscle insulin sensitivity but enhances endogenous glucose production
A Merovci, C Solis-Herrera, G Daniele, R Eldor, TV Fiorentino, D Tripathy, ...
The Journal of clinical investigation 124 (2), 509-514, 2014
8642014
Renal, metabolic and cardiovascular considerations of SGLT2 inhibition
RA DeFronzo, L Norton, M Abdul-Ghani
Nature Reviews Nephrology 13 (1), 11-26, 2017
5322017
Role of sodium-glucose cotransporter 2 (SGLT 2) inhibitors in the treatment of type 2 diabetes
MA Abdul-Ghani, L Norton, RA DeFronzo
Endocrine reviews 32 (4), 515-531, 2011
4932011
Novel hypothesis to explain why SGLT2 inhibitors inhibit only 30–50% of filtered glucose load in humans
MA Abdul-Ghani, RA DeFronzo, L Norton
Diabetes 62 (10), 3324-3328, 2013
2532013
Dapagliflozin enhances fat oxidation and ketone production in patients with type 2 diabetes
G Daniele, J Xiong, C Solis-Herrera, A Merovci, R Eldor, D Tripathy, ...
Diabetes care 39 (11), 2036-2041, 2016
2032016
Distinct β-cell defects in impaired fasting glucose and impaired glucose tolerance
M Kanat, A Mari, L Norton, D Winnier, RA DeFronzo, C Jenkinson, ...
Diabetes 61 (2), 447-453, 2012
1522012
Renal sodium-glucose cotransporter inhibition in the management of type 2 diabetes mellitus
MA Abdul-Ghani, L Norton, RA DeFronzo
American Journal of Physiology-Renal Physiology 309 (11), F889-F900, 2015
1512015
Efficacy and safety of SGLT2 inhibitors in the treatment of type 2 diabetes mellitus
MA Abdul-Ghani, L Norton, RA DeFronzo
Current diabetes reports 12, 230-238, 2012
1502012
The diabetes gene and Wnt pathway effector TCF7L2 regulates adipocyte development and function
X Chen, I Ayala, C Shannon, M Fourcaudot, NK Acharya, CP Jenkinson, ...
Diabetes 67 (4), 554-568, 2018
1162018
Insulin: The master regulator of glucose metabolism
L Norton, C Shannon, A Gastaldelli, RA DeFronzo
Metabolism 129, 155142, 2022
1032022
High-fat/low-carbohydrate diet reduces insulin-stimulated carbohydrate oxidation but stimulates nonoxidative glucose disposal in humans: An important role for skeletal muscle …
K Chokkalingam, K Jewell, L Norton, J Littlewood, LJC Van Loon, ...
The Journal of Clinical Endocrinology & Metabolism 92 (1), 284-292, 2007
1022007
Lactate elicits ER-mitochondrial Mg2+ dynamics to integrate cellular metabolism
CC Daw, K Ramachandran, BT Enslow, S Maity, B Bursic, MJ Novello, ...
Cell 183 (2), 474-489. e17, 2020
982020
Chromatin occupancy of transcription factor 7-like 2 (TCF7L2) and its role in hepatic glucose metabolism
L Norton, M Fourcaudot, MA Abdul-Ghani, D Winnier, FF Mehta, ...
Diabetologia 54, 3132-3142, 2011
952011
Sodium‐glucose co‐transporter (SGLT) and glucose transporter (GLUT) expression in the kidney of type 2 diabetic subjects
L Norton, CE Shannon, M Fourcaudot, C Hu, N Wang, W Ren, J Song, ...
Diabetes, Obesity and Metabolism 19 (9), 1322-1326, 2017
872017
Impaired early-but not late-phase insulin secretion in subjects with impaired fasting glucose
M Kanat, L Norton, D Winnier, C Jenkinson, RA DeFronzo, ...
Acta diabetologica 48, 209-217, 2011
812011
Elevated free fatty acids attenuate the insulin-induced suppression of PDK4 gene expression in human skeletal muscle: potential role of intramuscular long-chain acyl-coenzyme A
K Tsintzas, K Chokkalingam, K Jewell, L Norton, IA Macdonald, ...
The Journal of Clinical Endocrinology & Metabolism 92 (10), 3967-3972, 2007
812007
FGF21 is an insulin-dependent postprandial hormone in adult humans
RJ Samms, JE Lewis, L Norton, FB Stephens, CJ Gaffney, T Butterfield, ...
The Journal of Clinical Endocrinology & Metabolism 102 (10), 3806-3813, 2017
782017
The relationship between β-cell function and glycated hemoglobin: results from the veterans administration genetic epidemiology study
M Kanat, D Winnier, L Norton, N Arar, C Jenkinson, RA DeFronzo, ...
Diabetes care 34 (4), 1006-1010, 2011
752011
Empagliflozin and kinetics of renal glucose transport in healthy individuals and individuals with type 2 diabetes
H Al-Jobori, G Daniele, E Cersosimo, C Triplitt, R Mehta, L Norton, ...
Diabetes 66 (7), 1999-2006, 2017
722017
Blockade of MCU-mediated Ca2+ uptake perturbs lipid metabolism via PP4-dependent AMPK dephosphorylation
D Tomar, F Jaña, Z Dong, WJ Quinn, P Jadiya, SL Breves, CC Daw, ...
Cell reports 26 (13), 3709-3725. e7, 2019
642019
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