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Yoon-Sim Yap
Yoon-Sim Yap
National Cancer Centre Singapore
Geverifieerd e-mailadres voor nus.edu.sg
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Ribociclib as first-line therapy for HR-positive, advanced breast cancer
GN Hortobagyi, SM Stemmer, HA Burris, YS Yap, GS Sonke, ...
New England journal of medicine 375 (18), 1738-1748, 2016
18032016
Updated results from MONALEESA-2, a phase III trial of first-line ribociclib plus letrozole versus placebo plus letrozole in hormone receptor-positive, HER2-negative advanced …
GN Hortobagyi, SM Stemmer, HA Burris, YS Yap, GS Sonke, ...
Annals of Oncology 29 (7), 1541-1547, 2018
7462018
Neratinib after trastuzumab-based adjuvant therapy in HER2-positive breast cancer (ExteNET): 5-year analysis of a randomised, double-blind, placebo-controlled, phase 3 trial
M Martin, FA Holmes, B Ejlertsen, S Delaloge, B Moy, H Iwata, ...
The lancet oncology 18 (12), 1688-1700, 2017
6402017
Everolimus for women with trastuzumab-resistant, HER2-positive, advanced breast cancer (BOLERO-3): a randomised, double-blind, placebo-controlled phase 3 trial
F André, R O'Regan, M Ozguroglu, M Toi, B Xu, G Jerusalem, N Masuda, ...
The lancet oncology 15 (6), 580-591, 2014
5632014
Neratinib plus capecitabine versus lapatinib plus capecitabine in HER2-positive metastatic breast cancer previously treated with≥ 2 HER2-directed regimens: phase III NALA trial
C Saura, M Oliveira, YH Feng, MS Dai, SW Chen, SA Hurvitz, SB Kim, ...
Journal of Clinical Oncology 38 (27), 3138, 2020
4502020
PI3K/Akt/mTOR inhibitors in breast cancer
JJX Lee, K Loh, YS Yap
Cancer biology & medicine 12 (4), 342, 2015
3102015
Adjuvant abemaciclib combined with endocrine therapy for high-risk early breast cancer: updated efficacy and Ki-67 analysis from the monarchE study
N Harbeck, P Rastogi, M Martin, SM Tolaney, ZM Shao, PA Fasching, ...
Annals of Oncology 32 (12), 1571-1581, 2021
2962021
Overall survival with ribociclib plus letrozole in advanced breast cancer
GN Hortobagyi, SM Stemmer, HA Burris, YS Yap, GS Sonke, L Hart, ...
New England Journal of Medicine 386 (10), 942-950, 2022
2942022
The NF1 gene revisited–from bench to bedside
YS Yap, JR McPherson, CK Ong, SG Rozen, BT Teh, ASG Lee, DF Callen
Oncotarget 5 (15), 5873, 2014
245*2014
Adjuvant aromatase inhibitors for early breast cancer after chemotherapy-induced amenorrhoea: caution and suggested guidelines
IE Smith, M Dowsett, YS Yap, G Walsh, PE Lønning, RJ Santen, D Hayes
Journal of Clinical Oncology 24 (16), 2444-2447, 2006
2452006
Association of proinflammatory cytokines and chemotherapy-associated cognitive impairment in breast cancer patients: a multi-centered, prospective, cohort study
YT Cheung, T Ng, M Shwe, HK Ho, KM Foo, MT Cham, JA Lee, G Fan, ...
Annals of Oncology 26 (7), 1446-1451, 2015
2252015
Clinical validation of an ultra high-throughput spiral microfluidics for the detection and enrichment of viable circulating tumor cells
BL Khoo, ME Warkiani, DSW Tan, AAS Bhagat, D Irwin, DP Lau, AST Lim, ...
PloS one 9 (7), e99409, 2014
2172014
Tamoxifen metabolism predicts drug concentrations and outcome in premenopausal patients with early breast cancer
P Saladores, T Mürdter, D Eccles, B Chowbay, NK Zgheib, S Winter, ...
The pharmacogenomics journal 15 (1), 84-94, 2015
2092015
An ultra-high-throughput spiral microfluidic biochip for the enrichment of circulating tumor cells
ME Warkiani, BL Khoo, DSW Tan, AAS Bhagat, WT Lim, YS Yap, SC Lee, ...
Analyst 139 (13), 3245-3255, 2014
2072014
Genotype-phenotype correlation in NF1: evidence for a more severe phenotype associated with missense mutations affecting NF1 codons 844–848
M Koczkowska, Y Chen, T Callens, A Gomes, A Sharp, S Johnson, ...
The American Journal of Human Genetics 102 (1), 69-87, 2018
1932018
Impact of CYP2D6, CYP3A5, CYP2C9 and CYP2C19 polymorphisms on tamoxifen pharmacokinetics in Asian breast cancer patients
JSL Lim, XA Chen, O Singh, YS Yap, RCH Ng, NS Wong, M Wong, ...
British journal of clinical pharmacology 71 (5), 737-750, 2011
1522011
Chromosome 1q21. 3 amplification is a trackable biomarker and actionable target for breast cancer recurrence
JY Goh, M Feng, W Wang, G Oguz, SMJM Yatim, PL Lee, Y Bao, TH Lim, ...
Nature medicine 23 (11), 1319-1330, 2017
1422017
Neratinib+ capecitabine versus lapatinib+ capecitabine in patients with HER2+ metastatic breast cancer previously treated with≥ 2 HER2-directed regimens: Findings from the …
C Saura, M Oliveira, YH Feng, MS Dai, SA Hurvitz, SB Kim, B Moy, ...
Journal of Clinical Oncology 37 (15_suppl), 1002-1002, 2019
1282019
Minimal clinically important difference (MCID) for the functional assessment of cancer therapy: cognitive function (FACT-Cog) in breast cancer patients
YT Cheung, YL Foo, M Shwe, YP Tan, G Fan, WS Yong, P Madhukumar, ...
Journal of clinical epidemiology 67 (7), 811-820, 2014
1152014
Minimal clinically important difference (MCID) for the functional assessment of cancer therapy: cognitive function (FACT-Cog) in breast cancer patients
YT Cheung, YL Foo, M Shwe, YP Tan, G Fan, WS Yong, P Madhukumar, ...
Journal of clinical epidemiology 67 (7), 811-820, 2014
1152014
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