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Christine Toelzer
Christine Toelzer
Geverifieerd e-mailadres voor bristol.ac.uk
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Free fatty acid binding pocket in the locked structure of SARS-CoV-2 spike protein
C Toelzer, K Gupta, SKN Yadav, U Borucu, AD Davidson, ...
Science 370 (6517), 725-730, 2020
3672020
Molecular simulations suggest vitamins, retinoids and steroids as ligands of the free fatty acid pocket of the SARS‐CoV‐2 Spike protein
DK Shoemark, CK Colenso, C Toelzer, K Gupta, RB Sessions, ...
Angewandte Chemie 133 (13), 7174-7186, 2021
892021
Multibac: baculovirus-mediated multigene DNA cargo delivery in insect and mammalian cells
K Gupta, C Tölzer, D Sari-Ak, DJ Fitzgerald, C Schaffitzel, I Berger
Viruses 11 (3), 198, 2019
342019
Large expert-curated database for benchmarking document similarity detection in biomedical literature search
P Brown, AC Tan, MA El-Esawi, T Liehr, O Blanck, DP Gladue, ...
Database 2019, 2019
342019
Arabidopsis immunity regulator EDS1 in a PAD4/SAG101-unbound form is a monomer with an inherently inactive conformation
M Voss, C Toelzer, DD Bhandari, JE Parker, K Niefind
Journal of structural biology 208 (3), 107390, 2019
282019
Control of Chiral Magnetism Through Electric Fields in Multiferroic Compounds above the Long-Range Multiferroic Transition
MB J. Stein, M. Baum, S. Holbein, T. Finger, T. Cronert, C. Tölzer, T ...
Physical Review Letters, 2017
272017
The free fatty acid–binding pocket is a conserved hallmark in pathogenic β-coronavirus spike proteins from SARS-CoV to Omicron
C Toelzer, K Gupta, SKN Yadav, L Hodgson, MK Williamson, D Buzas, ...
Science Advances 8 (47), eadc9179, 2022
232022
Structural insights in cell-type specific evolution of intra-host diversity by SARS-CoV-2
K Gupta, C Toelzer, MK Williamson, DK Shoemark, ASF Oliveira, ...
Nature communications 13 (1), 222, 2022
232022
Biological properties and structural study of new aminoalkyl derivatives of benzimidazole and benzotriazole, dual inhibitors of CK2 and PIM1 kinases
K Chojnacki, P Wińska, M Wielechowska, E Łukowska-Chojnacka, ...
Bioorganic Chemistry 80, 266-275, 2018
212018
Highly efficient CRISPR-mediated large DNA docking and multiplexed prime editing using a single baculovirus
F Aulicino, M Pelosse, C Toelzer, J Capin, E Ilegems, P Meysami, ...
Nucleic Acids Research 50 (13), 7783-7799, 2022
192022
Synthesis, biological properties and structural study of new halogenated azolo [4, 5-b] pyridines as inhibitors of CK2 kinase
K Chojnacki, D Lindenblatt, P Wińska, M Wielechowska, C Toelzer, ...
Bioorganic chemistry 106, 104502, 2021
132021
Cryo-EM reveals binding of linoleic acid to SARS-CoV-2 spike glycoprotein, suggesting an antiviral treatment strategy
C Toelzer, K Gupta, I Berger, C Schaffitzel
Acta Crystallographica Section D: Structural Biology 79 (2), 111-121, 2023
102023
A novel esterase subfamily with α/β‐hydrolase fold suggested by structures of two bacterial enzymes homologous to l‐homoserine O‐acetyl transferases
C Tölzer, S Pal, H Watzlawick, J Altenbuchner, K Niefind
FEBS letters 590 (1), 174-184, 2016
82016
Structures of nonsense-mediated mRNA decay factors UPF3B and UPF3A in complex with UPF2 reveal molecular basis for competitive binding and for neurodevelopmental disorder …
JC Bufton, KT Powers, JYA Szeto, C Toelzer, I Berger, C Schaffitzel
Nucleic acids research 50 (10), 5934-5947, 2022
72022
The MultiBac BEVS: Basics, applications, performance and recent developments
B Gorda, C Toelzer, F Aulicino, I Berger
Methods in Enzymology 660, 129-154, 2021
62021
Crystallization and preliminary crystallographic analysis of cgHle, a homoserine acetyltransferase homologue, from Corynebacterium glutamicum
C Tölzer, S Pal, H Watzlawick, J Altenbuchner, K Niefind
Acta Crystallographica Section F: Structural Biology and Crystallization …, 2009
62009
The MultiBac system: a perspective
I Berger, C Tölzer, K Gupta
Emerging Topics in Life Sciences 3 (5), 477-482, 2019
42019
Structural basis for cell-type specific evolution of viral fitness by SARS-CoV-2
K Gupta, C Toelzer, MK Williamson, DK Shoemark, ASF Oliveira, ...
bioRxiv, 2021.05. 11.443384, 2021
32021
Expanding the Application Range of Microbial Oxidoreductases by an Alcohol Dehydrogenase from Comamonas testosteroni with a Broad Substrate Spectrum and …
D Bakonyi, C Toelzer, M Stricker, W Hummel, K Niefind, H Gröger
Catalysts 10 (11), 1281, 2020
32020
Improved protein-crystal identification by using 2, 2, 2-trichloroethanol as a fluorescence enhancer
C Pichlo, C Toelzer, K Chojnacki, S Öcal, M Uthoff, S Ruegenberg, ...
Acta Crystallographica Section F: Structural Biology Communications 74 (5 …, 2018
32018
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Artikelen 1–20