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Chichao Chen
Chichao Chen
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Verified email at takeda.com
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Cited by
Year
SOX2 promotes lineage plasticity and antiandrogen resistance in TP53-and RB1-deficient prostate cancer
P Mu, Z Zhang, M Benelli, WR Karthaus, E Hoover, CC Chen, ...
Science 355 (6320), 84-88, 2017
8852017
A combinatorial strategy for treating KRAS-mutant lung cancer
E Manchado, S Weissmueller, JP Morris, CC Chen, R Wullenkord, ...
Nature 534 (7609), 647-651, 2016
4102016
BRD4 connects enhancer remodeling to senescence immune surveillance
N Tasdemir, A Banito, JS Roe, D Alonso-Curbelo, M Camiolo, ...
Cancer discovery 6 (6), 612-629, 2016
324*2016
NK cell–mediated cytotoxicity contributes to tumor control by a cytostatic drug combination
M Ruscetti, J Leibold, MJ Bott, M Fennell, A Kulick, NR Salgado, CC Chen, ...
Science 362 (6421), 1416-1422, 2018
2912018
α-Ketoglutarate links p53 to cell fate during tumour suppression
JP Morris IV, JJ Yashinskie, R Koche, R Chandwani, S Tian, CC Chen, ...
Nature 573 (7775), 595-599, 2019
2172019
DNAJB1–PRKACA fusion kinase interacts with β-catenin and the liver regenerative response to drive fibrolamellar hepatocellular carcinoma
ER Kastenhuber, G Lalazar, SL Houlihan, DF Tschaharganeh, T Baslan, ...
Proceedings of the National Academy of Sciences 114 (50), 13076-13084, 2017
1472017
The SS18-SSX oncoprotein hijacks KDM2B-PRC1. 1 to drive synovial sarcoma
A Banito, X Li, AN Laporte, JS Roe, F Sanchez-Vega, CH Huang, ...
Cancer cell 33 (3), 527-541. e8, 2018
1322018
MAT2A inhibition blocks the growth of MTAP-deleted cancer cells by reducing PRMT5-dependent mRNA splicing and inducing DNA damage
P Kalev, ML Hyer, S Gross, Z Konteatis, CC Chen, M Fletcher, M Lein, ...
Cancer Cell, 2021
1212021
Loss of CHD1 promotes heterogeneous mechanisms of resistance to AR-targeted therapy via chromatin dysregulation
Z Zhang, C Zhou, X Li, SD Barnes, S Deng, E Hoover, CC Chen, YS Lee, ...
Cancer cell 37 (4), 584-598. e11, 2020
1082020
A gain-of-function p53-mutant oncogene promotes cell fate plasticity and myeloid leukemia through the pluripotency factor FOXH1
E Loizou, A Banito, G Livshits, YJ Ho, RP Koche, FJ Sánchez-Rivera, ...
Cancer discovery 9 (7), 962-979, 2019
682019
Vitamin B6 addiction in acute myeloid leukemia
CC Chen, B Li, SE Millman, C Chen, X Li, JP Morris, A Mayle, YJ Ho, ...
Cancer Cell 37 (1), 71-84. e7, 2020
582020
Cooperative loss of RAS feedback regulation drives myeloid leukemogenesis
Z Zhao, CC Chen, CD Rillahan, R Shen, T Kitzing, ME McNerney, ...
Nature genetics 47 (5), 539-543, 2015
482015
Onco-proteogenomics identifies urinary S100A9 and GRN as potential combinatorial biomarkers for early diagnosis of hepatocellular carcinoma
CH Huang, CJ Kuo, SS Liang, SW Chi, E Hsi, CC Chen, KT Lee, ...
BBA clinical 3, 205-213, 2015
472015
Impact of RNA-guided technologies for target identification and deconvolution
M Fennell, Q Xiang, A Hwang, C Chen, CH Huang, CC Chen, R Pelossof, ...
Journal of biomolecular screening 19 (10), 1327-1337, 2014
262014
MLL3 regulates the CDKN2A tumor suppressor locus in liver cancer
C Zhu, YM Soto-Feliciano, JP Morris, CH Huang, RP Koche, Y Ho, ...
Elife 12, e80854, 2023
62023
A preclinical platform for assessing antitumor effects and systemic toxicities of cancer drug targets
X Li, CH Huang, FJ Sánchez-Rivera, MC Kennedy, DF Tschaharganeh, ...
Proceedings of the National Academy of Sciences 119 (17), e2110557119, 2022
52022
Pancreatic Cancer
JP Morris IV, JJ Yashinskie, R Koche, R Chandwani, S Tian, CC Chen
12009
Timing of treatment shapes the path to androgen receptor signaling inhibitor resistance in prostate cancer
E Lee, Z Zhang, CC Chen, D Choi, ACA Rivera, E Linton, Y Ho, J Love, ...
bioRxiv, 2024.03. 18.585532, 2024
2024
Abstract NG06: CHD1-loss confers AR targeted therapy resistance via promoting cancer heterogeneity and lineage plasticity
Z Zhang, C Zhou, X Li, S Barnes, S Deng, E Hoover, CC Chen, YS Lee, ...
Cancer Research 80 (16_Supplement), NG06-NG06, 2020
2020
Targeted therapy-induced senescence enhances immune surveillance of KRAS mutant lung cancers
M Ruscetti, J Leibold, MJ Bott, M Shields, CC Chen, M Fennell, HC Chen, ...
Cancer Research 78 (10 Sup), 2018
2018
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