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Colin Stack
Colin Stack
University of Western Sydney
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Fasciola hepatica cathepsin L-like proteases: biology, function, and potential in the development of first generation liver fluke vaccines
JP Dalton, SO Neill, C Stack, P Collins, A Walshe, M Sekiya, S Doyle, ...
International journal for parasitology 33 (11), 1173-1181, 2003
3272003
Helminth 2-Cys peroxiredoxin drives Th2 responses through a mechanism involving alternatively activated macrophages
S Donnelly, CM Stack, SM O'Neill, AA Sayed, DL Williams, JP Dalton
The FASEB Journal 22 (11), 4022, 2008
2712008
Helminth 2-Cys peroxiredoxin drives Th2 responses through a mechanism involving alternatively activated macrophages
S Donnelly, CM Stack, SM O'Neill, AA Sayed, DL Williams, JP Dalton
The FASEB Journal 22 (11), 4022, 2008
2712008
Cathepsin L1, the major protease involved in liver fluke (Fasciola hepatica) virulence: propeptide cleavage sites and autoactivation of the zymogen secreted from gastrodermal cells
PR Collins, CM Stack, SM O'Neill, S Doyle, T Ryan, GP Brennan, ...
Journal of Biological Chemistry 279 (17), 17038-17046, 2004
1922004
Structural basis for the inhibition of the essential Plasmodium falciparum M1 neutral aminopeptidase
S McGowan, CJ Porter, J Lowther, CM Stack, SJ Golding, ...
Proceedings of the National Academy of Sciences 106 (8), 2537-2542, 2009
1772009
Structural basis for the inhibition of the essential Plasmodium falciparum M1 neutral aminopeptidase
S McGowan, CJ Porter, J Lowther, CM Stack, SJ Golding, ...
Proceedings of the National Academy of Sciences 106 (8), 2537-2542, 2009
1772009
Helminth cysteine proteases inhibit TRIF-dependent activation of macrophages via degradation of TLR3
S Donnelly, SM O’Neill, CM Stack, MW Robinson, L Turnbull, ...
Journal of Biological Chemistry 285 (5), 3383-3392, 2010
1672010
Characterization of the Plasmodium falciparum M17 leucyl aminopeptidase: a protease involved in amino acid regulation with potential for antimalarial drug development
CM Stack, J Lowther, E Cunningham, S Donnelly, DL Gardiner, ...
Journal of Biological Chemistry 282 (3), 2069-2080, 2007
1582007
Characterization of the Plasmodium falciparum M17 leucyl aminopeptidase: a protease involved in amino acid regulation with potential for antimalarial drug development
CM Stack, J Lowther, E Cunningham, S Donnelly, DL Gardiner, ...
Journal of Biological Chemistry 282 (3), 2069-2080, 2007
1582007
Plasmodium falciparum neutral aminopeptidases: new targets for anti-malarials
TS Skinner-Adams, CM Stack, KR Trenholme, CL Brown, J Grembecka, ...
Trends in biochemical sciences 35 (1), 53-61, 2010
1562010
Proteomics and phylogenetic analysis of the cathepsin L protease family of the helminth pathogen Fasciola hepatica: expansion of a repertoire of virulence-associated factors
MW Robinson, JF Tort, J Lowther, SM Donnelly, E Wong, W Xu, CM Stack, ...
Molecular & Cellular Proteomics 7 (6), 1111-1123, 2008
1562008
Protection of cattle against a natural infection of Fasciola hepatica by vaccination with recombinant cathepsin L1 (rFhCL1)
O Golden, RJ Flynn, C Read, M Sekiya, SM Donnelly, C Stack, JP Dalton, ...
Vaccine 28 (34), 5551-5557, 2010
1402010
Protection of cattle against a natural infection of Fasciola hepatica by vaccination with recombinant cathepsin L1 (rFhCL1)
O Golden, RJ Flynn, C Read, M Sekiya, SM Donnelly, C Stack, JP Dalton, ...
Vaccine 28 (34), 5551-5557, 2010
1402010
Leucine aminopeptidase of the human blood flukes, Schistosoma mansoni and Schistosoma japonicum
E McCarthy, C Stack, SM Donnelly, S Doyle, VH Mann, PJ Brindley, ...
International journal for parasitology 34 (6), 703-714, 2004
1192004
Leucine aminopeptidase of the human blood flukes, Schistosoma mansoni and Schistosoma japonicum
E McCarthy, C Stack, SM Donnelly, S Doyle, VH Mann, PJ Brindley, ...
International journal for parasitology 34 (6), 703-714, 2004
1192004
Structural and functional relationships in the virulence-associated cathepsin L proteases of the parasitic liver fluke, Fasciola hepatica
CM Stack, CR Caffrey, SM Donnelly, A Seshaadri, J Lowther, JF Tort, ...
Journal of Biological Chemistry 283 (15), 9896-9908, 2008
1122008
Structural and functional relationships in the virulence-associated cathepsin L proteases of the parasitic liver fluke, Fasciola hepatica
CM Stack, CR Caffrey, SM Donnelly, A Seshaadri, J Lowther, JF Tort, ...
Journal of Biological Chemistry 283 (15), 9896-9908, 2008
1122008
Identification of phosphinate dipeptide analog inhibitors directed against the Plasmodium falciparum M17 leucine aminopeptidase as lead antimalarial compounds
TS Skinner-Adams, J Lowther, F Teuscher, CM Stack, J Grembecka, ...
Journal of medicinal chemistry 50 (24), 6024-6031, 2007
1092007
Identification of phosphinate dipeptide analog inhibitors directed against the Plasmodium falciparum M17 leucine aminopeptidase as lead antimalarial compounds
TS Skinner-Adams, J Lowther, F Teuscher, CM Stack, J Grembecka, ...
Journal of medicinal chemistry 50 (24), 6024-6031, 2007
1092007
Structure of the Plasmodium falciparum M17 aminopeptidase and significance for the design of drugs targeting the neutral exopeptidases
S McGowan, CA Oellig, WA Birru, TT Caradoc-Davies, CM Stack, ...
Proceedings of the National Academy of Sciences 107 (6), 2449-2454, 2010
1002010
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