| Effects of xanomeline, a selective muscarinic receptor agonist, on cognitive function and behavioral symptoms in Alzheimer disease NC Bodick, WW Offen, AI Levey, NR Cutler, SG Gauthier, A Satlin, ... Archives of neurology 54 (4), 465-473, 1997 | 763 | 1997 |
| Pronounced pharmacologic deficits in M2 muscarinic acetylcholine receptor knockout mice J Gomeza, H Shannon, E Kostenis, C Felder, L Zhang, J Brodkin, ... Proceedings of the National Academy of Sciences 96 (4), 1692-1697, 1999 | 457 | 1999 |
| Enhancement of D1 dopamine receptor-mediated locomotor stimulation in M4 muscarinic acetylcholine receptor knockout mice J Gomeza, L Zhang, E Kostenis, C Felder, F Bymaster, J Brodkin, ... Proceedings of the National Academy of Sciences 96 (18), 10483-10488, 1999 | 375 | 1999 |
| Evaluation of the discriminative effects of morphine in the rat. HE Shannon, SG Holtzman Journal of Pharmacology and Experimental Therapeutics 198 (1), 54-65, 1976 | 260 | 1976 |
| Blockade of phencyclidine-induced hyperlocomotion by olanzapine, clozapine and serotonin receptor subtype selective antagonists in mice SD Gleason, HE Shannon Psychopharmacology 129, 79-84, 1997 | 258 | 1997 |
| Brain exposure of two selective dual CDK4 and CDK6 inhibitors and the antitumor activity of CDK4 and CDK6 inhibition in combination with temozolomide in an intracranial … TJ Raub, GN Wishart, P Kulanthaivel, BA Staton, RT Ajamie, GA Sawada, ... Drug Metabolism and Disposition 43 (9), 1360-1371, 2015 | 256 | 2015 |
| Efficacy of duloxetine, a potent and balanced serotonergic and noradrenergic reuptake inhibitor, in inflammatory and acute pain models in rodents CK Jones, SC Peters, HE Shannon Journal of Pharmacology and Experimental Therapeutics 312 (2), 726-732, 2005 | 208 | 2005 |
| Xanomeline, an M1/M4 preferring muscarinic cholinergic receptor agonist, produces antipsychotic-like activity in rats and mice HE Shannon, K Rasmussen, FP Bymaster, JC Hart, SC Peters, ... Schizophrenia research 42 (3), 249-259, 2000 | 200 | 2000 |
| Xanomeline: a novel muscarinic receptor agonist with functional selectivity for M1 receptors. HE Shannon, FP Bymaster, DO Calligaro, B Greenwood, CH Mitch, ... Journal of Pharmacology and Experimental Therapeutics 269 (1), 271-281, 1994 | 190 | 1994 |
| Evaluation of phencyclidine analogs on the basis of their discriminative stimulus properties in the rat. HE Shannon Journal of Pharmacology and Experimental Therapeutics 216 (3), 543-551, 1981 | 182 | 1981 |
| Comparative behavioral and neurochemical activities of cholinergic antagonists in rats. FP Bymaster, IAN Heath, JC Hendrix, HE Shannon Journal of Pharmacology and Experimental Therapeutics 267 (1), 16-24, 1993 | 177 | 1993 |
| Morphine training dose: a determinant of stimulus generalization to narcotic antagonists in the rat HE Shannon, SG Holtzman Psychopharmacology 61, 239-244, 1979 | 162 | 1979 |
| Comparison of the peripheral and central effects of the opioid agonists loperamide and morphine in the formalin test in rats HE Shannon, EA Lutz Neuropharmacology 42 (2), 253-261, 2002 | 153 | 2002 |
| The selective muscarinic agonist xanomeline improves both the cognitive deficits and behavioral symptoms of Alzheimer disease. NC Bodick, WW Offen, HE Shannon, J Satterwhite, R Lucas, R Van Lier, ... Alzheimer disease and associated disorders 11, S16-22, 1997 | 150 | 1997 |
| Small-molecule covalent modification of conserved cysteine leads to allosteric inhibition of the TEAD⋅ Yap protein-protein interaction K Bum-Erdene, D Zhou, G Gonzalez-Gutierrez, MK Ghozayel, Y Si, D Xu, ... Cell chemical biology 26 (3), 378-389. e13, 2019 | 143 | 2019 |
| Comparison of the effect of glutamate receptor modulators in the 6 Hz and maximal electroshock seizure models ME Barton, SC Peters, HE Shannon Epilepsy research 56 (1), 17-26, 2003 | 135 | 2003 |
| Anxiolytic-like activity of the mGLU2/3 receptor agonist LY354740 in the elevated plus maze test is disrupted in metabotropic glutamate receptor 2 and 3 knock-out mice AM Linden, H Shannon, M Baez, JL Yu, A Koester, DD Schoepp Psychopharmacology 179, 284-291, 2005 | 132 | 2005 |
| Xanomeline: a selective muscarinic agonist for the treatment of Alzheimer's disease FP Bymaster, CA Whitesitt, HE Shannon, N DeLapp, JS Ward, ... Drug Development Research 40 (2), 158-170, 1997 | 131 | 1997 |
| Further evaluation of the discriminative effects of morphine in the rat. HE Shannon, SG Holtzman Journal of Pharmacology and Experimental Therapeutics 201 (1), 55-66, 1977 | 130 | 1977 |
| Muscarinic cholinergic modulation of prepulse inhibition of the acoustic startle reflex CK Jones, HE Shannon Journal of Pharmacology and Experimental Therapeutics 294 (3), 1017-1023, 2000 | 127 | 2000 |
