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Linda Holmfeldt
Linda Holmfeldt
Andere namenLinda U Johansson
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The genetic basis of early T-cell precursor acute lymphoblastic leukaemia
J Zhang, L Ding, L Holmfeldt, G Wu, SL Heatley, D Payne-Turner, ...
Nature 481 (7380), 157-163, 2012
17872012
The genomic landscape of hypodiploid acute lymphoblastic leukemia
L Holmfeldt, L Wei, E Diaz-Flores, M Walsh, J Zhang, L Ding, ...
Nature genetics 45 (3), 242-252, 2013
7842013
CREBBP mutations in relapsed acute lymphoblastic leukaemia
CG Mullighan, J Zhang, LH Kasper, S Lerach, D Payne-Turner, ...
Nature 471 (7337), 235-239, 2011
6962011
CREST maps somatic structural variation in cancer genomes with base-pair resolution
J Wang, CG Mullighan, J Easton, S Roberts, SL Heatley, J Ma, MC Rusch, ...
Nature methods 8 (8), 652-654, 2011
5612011
The landscape of somatic mutations in infant MLL-rearranged acute lymphoblastic leukemias
AK Andersson, J Ma, J Wang, X Chen, AL Gedman, J Dang, J Nakitandwe, ...
Nature genetics 47 (4), 330-337, 2015
505*2015
Contrasting roles of histone 3 lysine 27 demethylases in acute lymphoblastic leukaemia
P Ntziachristos, A Tsirigos, GG Welstead, T Trimarchi, S Bakogianni, L Xu, ...
Nature 514 (7523), 513-517, 2014
3772014
The BCL11B tumor suppressor is mutated across the major molecular subtypes of T-cell acute lymphoblastic leukemia
A Gutierrez, A Kentsis, T Sanda, L Holmfeldt, SC Chen, J Zhang, ...
Blood, The Journal of the American Society of Hematology 118 (15), 4169-4173, 2011
1962011
NALP3 inflammasome upregulation and CASP1 cleavage of the glucocorticoid receptor cause glucocorticoid resistance in leukemia cells
SW Paugh, EJ Bonten, D Savic, LB Ramsey, WE Thierfelder, P Gurung, ...
Nature genetics 47 (6), 607-614, 2015
1572015
Cell of origin strongly influences genetic selection in a mouse model of T-ALL
KE Berquam-Vrieze, K Nannapaneni, BT Brett, L Holmfeldt, J Ma, ...
Blood, The Journal of the American Society of Hematology 118 (17), 4646-4656, 2011
1252011
The guanosine tetraphosphate (ppGpp) alarmone, DksA and promoter affinity for RNA polymerase in regulation of σ54‐dependent transcription
LMD Bernardo, LUM Johansson, D Solera, E Skärfstad, V Shingler
Molecular microbiology 60 (3), 749-764, 2006
1052006
CONSERTING: integrating copy-number analysis with structural-variation detection
X Chen, P Gupta, J Wang, J Nakitandwe, K Roberts, JD Dalton, M Parker, ...
Nature methods 12 (6), 527-530, 2015
782015
Rare allelic forms of PRDM9 associated with childhood leukemogenesis
J Hussin, D Sinnett, F Casals, Y Idaghdour, V Bruat, V Saillour, J Healy, ...
Genome research 23 (3), 419-430, 2013
672013
Properties of RNA polymerase bypass mutants: implications for the role of ppGpp and its co-factor DksA in controlling transcription dependent on σ54
A Szalewska-Palasz, LUM Johansson, LMD Bernardo, E Skärfstad, ...
Journal of Biological Chemistry 282 (25), 18046-18056, 2007
662007
Genomic characterization of relapsed acute myeloid leukemia reveals novel putative therapeutic targets
S Stratmann, SA Yones, M Mayrhofer, N Norgren, A Skaftason, J Sun, ...
Blood Advances 5 (3), 900-912, 2021
412021
σ54-promoter discrimination and regulation by ppGpp and DksA
LMD Bernardo, LUM Johansson, E Skärfstad, V Shingler
Journal of Biological Chemistry 284 (2), 828-838, 2009
402009
σ54‐RNA polymerase controls σ70‐dependent transcription from a non‐overlapping divergent promoter
LUM Johansson, D Solera, LMD Bernardo, JA Moscoso, V Shingler
Molecular microbiology 70 (3), 709-723, 2008
322008
The role of TET2 in hematologic neoplasms
L Holmfeldt, CG Mullighan
Cancer cell 20 (1), 1-2, 2011
262011
Transcriptomic analysis reveals proinflammatory signatures associated with acute myeloid leukemia progression
S Stratmann, SA Yones, M Garbulowski, J Sun, A Skaftason, M Mayrhofer, ...
Blood advances 6 (1), 152-164, 2022
182022
A hyper-mutant of the unusual σ70-Pr promoter bypasses synergistic ppGpp/DksA co-stimulation
T del Peso-Santos, LMD Bernardo, E Skärfstad, L Holmfeldt, P Togneri, ...
Nucleic acids research 39 (14), 5853-5865, 2011
162011
Whole Genome Sequence Analysis of 22 MLL Rearranged Infant Acute Lymphoblastic Leukemias Reveals Remarkably Few Somatic Mutations: A Report From the …
AK Andersson, J Ma, J Wang, X Chen, M Rusch, G Wu, J Easton, ...
Blood, The Journal of the American Society of Hematology 118 (21), 69-69, 2011
132011
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Artikelen 1–20