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J. M. Gottesfeld
J. M. Gottesfeld
Geverifieerd e-mailadres voor scripps.edu
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Dynamic changes in the copy number of pluripotency and cell proliferation genes in human ESCs and iPSCs during reprogramming and time in culture
LC Laurent, I Ulitsky, I Slavin, H Tran, A Schork, R Morey, C Lynch, ...
Cell stem cell 8 (1), 106-118, 2011
10202011
Regulation of gene expression by small molecules
JM Gottesfeld, L Neely, JW Trauger, EE Baird, PB Dervan
Nature 387 (6629), 202-205, 1997
6791997
Histone deacetylase inhibitors reverse gene silencing in Friedreich's ataxia
D Herman, K Jenssen, R Burnett, E Soragni, SL Perlman, JM Gottesfeld
Nature chemical biology 2 (10), 551-558, 2006
5052006
Mitotic repression of the transcriptional machinery
JM Gottesfeld, DJ Forbes
Trends in biochemical sciences 22 (6), 197-202, 1997
4631997
Zinc finger protein derivatives and methods therefor
CF Barbas III, JM Gottesfeld, PE Wright
US Patent 6,140,466, 2000
4222000
Zinc finger protein derivatives and methods therefor
CF Barbas III, JM Gottesfeld, PE Wright
US Patent 6,242,568, 2001
3992001
Inhibition of RNA polymerase II transcription in human cells by synthetic DNA-binding ligands
LA Dickinson, RJ Gulizia, JW Trauger, EE Baird, DE Mosier, JM Gottesfeld, ...
Proceedings of the National Academy of Sciences 95 (22), 12890-12895, 1998
3681998
The HDAC inhibitor 4b ameliorates the disease phenotype and transcriptional abnormalities in Huntington's disease transgenic mice
EA Thomas, G Coppola, PA Desplats, B Tang, E Soragni, R Burnett, ...
Proceedings of the National Academy of Sciences 105 (40), 15564-15569, 2008
3372008
Reduced histone deacetylase 7 activity restores function to misfolded CFTR in cystic fibrosis
DM Hutt, D Herman, APC Rodrigues, S Noel, JM Pilewski, J Matteson, ...
Nature chemical biology 6 (1), 25-33, 2010
2812010
HDAC inhibitors correct frataxin deficiency in a Friedreich ataxia mouse model
M Rai, E Soragni, K Jenssen, R Burnett, D Herman, G Coppola, ...
PloS one 3 (4), e1958, 2008
2562008
Partial purification of the template-active fraction of chromatin: a preliminary report
JM Gottesfeld, WT Garrard, G Bagi, RF Wilson, J Bonner
Proceedings of the National Academy of Sciences 71 (6), 2193-2197, 1974
2551974
Friedreich's ataxia induced pluripotent stem cells model intergenerational GAA⋅ TTC triplet repeat instability
S Ku, E Soragni, E Campau, EA Thomas, G Altun, LC Laurent, JF Loring, ...
Cell stem cell 7 (5), 631-637, 2010
2432010
Solution structure of the first three zinc fingers of TFIIIA bound to the cognate DNA sequence: determinants of affinity and sequence specificity
DS Wuttke, MP Foster, DA Case, JM Gottesfeld, PE Wright
Journal of molecular biology 273 (1), 183-206, 1997
2431997
Pimelic diphenylamide 106 is a slow, tight-binding inhibitor of class I histone deacetylases
CJ Chou, D Herman, JM Gottesfeld
Journal of Biological Chemistry 283 (51), 35402-35409, 2008
2302008
Assembly of transcriptionally active 5S RNA gene chromatin in vitro
J Gottesfeld, LS Bloomer
Cell 28 (4), 781-791, 1982
2091982
Crystal structures of nucleosome core particles in complex with minor groove DNA-binding ligands
RK Suto, RS Edayathumangalam, CL White, C Melander, JM Gottesfeld, ...
Journal of molecular biology 326 (2), 371-380, 2003
2052003
Molecular basis for specific recognition of both RNA and DNA by a zinc finger protein
KR Clemens, V Wolf, SJ McBryant, P Zhang, X Liao, PE Wright, ...
Science 260 (5107), 530-533, 1993
1841993
Histone deacetylase (HDAC) inhibitors targeting HDAC3 and HDAC1 ameliorate polyglutamine-elicited phenotypes in model systems of Huntington's disease
H Jia, J Pallos, V Jacques, A Lau, B Tang, A Cooper, A Syed, J Purcell, ...
Neurobiology of disease 46 (2), 351-361, 2012
1722012
Two new pimelic diphenylamide HDAC inhibitors induce sustained frataxin upregulation in cells from Friedreich's ataxia patients and in a mouse model
M Rai, E Soragni, CJ Chou, G Barnes, S Jones, JR Rusche, JM Gottesfeld, ...
PloS one 5 (1), e8825, 2010
1722010
Domain packing and dynamics in the DNA complex of the N-terminal zinc fingers of TFIIIA.
MP Foster, DS Wuttke, I Radhakrishnan, DA Case, JM Gottesfeld, ...
Nature structural biology 4 (8), 605-608, 1997
1721997
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Artikelen 1–20