Geoff Macintyre
Geoff Macintyre
Computational Oncology Group Leader, CNIO, Madrid, Spain
Geverifieerd e-mailadres voor cnio.es - Homepage
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Pan-cancer analysis of whole genomes
I The, TPCA of Whole, Genomes Consortium
Nature 578 (7793), 82, 2020
3822020
Tracking the origins and drivers of subclonal metastatic expansion in prostate cancer
MKH Hong*, G Macintyre*, DC Wedge*, P Van Loo, K Patel, S Lunke, ...
Nature Communications 6, 2015
2862015
The evolutionary history of 2,658 cancers
M Gerstung, C Jolly, I Leshchiner, SC Dentro, S Gonzalez, D Rosebrock, ...
Nature 578 (7793), 122-128, 2020
2632020
Genome-wide analysis distinguishes hyperglycemia regulated epigenetic signatures of primary vascular cells
L Pirola, A Balcerczyk, RW Tothill, I Haviv, A Kaspi, S Lunke, M Ziemann, ...
Genome research 21 (10), 1601-1615, 2011
1852011
Copy number signatures and mutational processes in ovarian carcinoma
G Macintyre, TE Goranova, D De Silva, D Ennis, AM Piskorz, M Eldridge, ...
Nature genetics 50 (9), 1262-1270, 2018
1422018
is-rSNP: a novel technique for in silico regulatory SNP detection
G Macintyre, J Bailey, I Haviv, A Kowalczyk
Bioinformatics 26 (18), i524-i530, 2010
1352010
Reducing the risk of false discovery enabling identification of biologically significant genome-wide methylation status using the HumanMethylation450 array
H Naeem, NC Wong, Z Chatterton, MKH Hong, JS Pedersen, ...
BMC genomics 15 (1), 1-15, 2014
1182014
Molecular Profiling of Human Mammary Gland Links Breast Cancer Risk to a p27+ Cell Population with Progenitor Characteristics
S Choudhury, V Almendro, VF Merino, Z Wu, R Maruyama, Y Su, ...
Cell stem cell, 2013
942013
Socrates: identification of genomic rearrangements in tumour genomes by re-aligning soft clipped reads
J Schröder, A Hsu, SE Boyle, G Macintyre, M Cmero, RW Tothill, ...
Bioinformatics 30 (8), 1064-1072, 2014
752014
A urinary microRNA signature can predict the presence of bladder urothelial carcinoma in patients undergoing surveillance
N Sapre, G Macintyre, M Clarkson, H Naeem, M Cmero, A Kowalczyk, ...
British journal of cancer 114 (4), 454-462, 2016
512016
Curated microRNAs in urine and blood fail to validate as predictive biomarkers for high-risk prostate cancer
N Sapre, MKH Hong, G Macintyre, H Lewis, A Kowalczyk, AJ Costello, ...
PloS one 9 (4), e91729, 2014
482014
Canonical androstenedione reduction is the predominant source of signaling androgens in hormone-refractory prostate cancer
M Fankhauser, Y Tan, G Macintyre, I Haviv, MKH Hong, A Nguyen, ...
Clinical Cancer Research 20 (21), 5547-5557, 2014
462014
Sequencing Structural Variants in Cancer for Precision Therapeutics
G Macintyre, B Ylstra, JD Brenton
Trends in Genetics 32 (9), 530-542, 2016
452016
Portraits of genetic intra-tumour heterogeneity and subclonal selection across cancer types
SC Dentro, I Leshchiner, K Haase, M Tarabichi, J Wintersinger, ...
BioRxiv, 312041, 2018
302018
Unraveling tumor–immune heterogeneity in advanced ovarian cancer uncovers immunogenic effect of chemotherapy
A Jiménez-Sánchez, P Cybulska, KLV Mager, S Koplev, O Cast, ...
Nature Genetics, 1-12, 2020
272020
How subclonal modeling is changing the metastatic paradigm
G Macintyre, P Van Loo, NM Corcoran, DC Wedge, F Markowetz, ...
Clinical Cancer Research 23 (3), 630-635, 2017
272017
Associating disease-related genetic variants in intergenic regions to the genes they impact
G Macintyre, AJ Yepes, CS Ong, K Verspoor
PeerJ 2, e639, 2014
272014
Methanol-based fixation is superior to buffered formalin for next-generation sequencing of DNA from clinical cancer samples
AM Piskorz, D Ennis, G Macintyre, TE Goranova, M Eldridge, ...
Annals of Oncology 27 (3), 532-539, 2016
212016
Using Gene Ontology annotations in exploratory microarray clustering to understand cancer etiology
G Macintyre, J Bailey, D Gustafsson, I Haviv, A Kowalczyk
Pattern Recognition Letters 31 (14), 2138-2146, 2010
192010
Comparing nodal versus bony metastatic spread using tumour phylogenies
S Mangiola, MKH Hong, M Cmero, N Kurganovs, A Ryan, AJ Costello, ...
Scientific reports 6 (1), 1-10, 2016
182016
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Artikelen 1–20