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Enrico Guarnera
Enrico Guarnera
Principal Scientist @ Merck KGaA Healthcare
Geverifieerd e-mailadres voor merckgroup.com
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Jaar
Insulin-Degrading Enzyme in the Fight against Alzheimer’s Disease
IV Kurochkin, E Guarnera, IN Berezovsky
Trends in pharmacological sciences, 2018
1612018
Pathways and intermediates of amyloid fibril formation
R Pellarin, E Guarnera, A Caflisch
Journal of molecular biology 374 (4), 917-924, 2007
1462007
Amyloid fibril polymorphism is under kinetic control
R Pellarin, P Schuetz, E Guarnera, A Caflisch
Journal of the American Chemical Society 132 (42), 14960-14970, 2010
1362010
Allosteric sites: remote control in regulation of protein activity
E Guarnera, IN Berezovsky
Current opinion in structural biology 37, 1-8, 2016
1312016
Structure-based statistical mechanical model accounts for the causality and energetics of allosteric communication
E Guarnera, IN Berezovsky
PLoS computational biology 12 (3), e1004678, 2016
1152016
AlloSigMA: allosteric signaling and mutation analysis server
E Guarnera, ZW Tan, Z Zheng, IN Berezovsky
Bioinformatics 33 (24), 3996-3998, 2017
1002017
Allosteric drugs and mutations: chances, challenges, and necessity
E Guarnera, IN Berezovsky
Current opinion in structural biology 62, 149-157, 2020
752020
On the perturbation nature of allostery: sites, mutations, and signal modulation
E Guarnera, IN Berezovsky
Current opinion in structural biology 56, 18-27, 2019
752019
The telomere-binding protein Tbf1 demarcates snoRNA gene promoters in Saccharomyces cerevisiae
M Preti, C Ribeyre, C Pascali, MC Bosio, B Cortelazzi, J Rougemont, ...
Molecular cell 38 (4), 614-620, 2010
752010
Reversing allosteric communication: From detecting allosteric sites to inducing and tuning targeted allosteric response
WV Tee, E Guarnera, IN Berezovsky
PLoS computational biology 14 (6), e1006228, 2018
682018
AlloSigMA 2: paving the way to designing allosteric effectors and to exploring allosteric effects of mutations
ZW Tan, E Guarnera, WV Tee, IN Berezovsky
Nucleic acids research 48 (W1), W116-W124, 2020
582020
Toward Comprehensive Allosteric Control over Protein Activity
E Guarnera, IN Berezovsky
Structure 27, 1-13, 2019
562019
Toward allosterically increased catalytic activity of insulin degrading enzyme (IDE) against amyloid peptides
IV Kurochkin, E Guarnera, JH Wong, F Eisenhaber, IN Berezovsky
Biochemistry, 2016
552016
AlloMAPS: allosteric mutation analysis and polymorphism of signaling database
ZW Tan, WV Tee, E Guarnera, L Booth, IN Berezovsky
Nucleic acids research 47 (D1), D265-D270, 2019
502019
Estimation of protein folding probability from equilibrium simulations
F Rao, G Settanni, E Guarnera, A Caflisch
The Journal of chemical physics 122 (18), 2005
492005
Basic units of protein structure, folding, and function
IN Berezovsky, E Guarnera, Z Zheng
Progress in biophysics and molecular biology 128, 85-99, 2017
462017
Protein function machinery: from basic structural units to modulation of activity
IN Berezovsky, E Guarnera, Z Zheng, B Eisenhaber, F Eisenhaber
Current opinion in structural biology 42, 67-74, 2017
432017
On the allosteric effect of nsSNPs and the emerging importance of allosteric polymorphism
WV Tee, E Guarnera, IN Berezovsky
Journal of molecular biology 431 (19), 3933-3942, 2019
352019
How does a simplified-sequence protein fold?
E Guarnera, R Pellarin, A Caflisch
Biophysical journal 97 (6), 1737-1746, 2009
282009
Allosteric perspective on the mutability and druggability of the SARS-CoV-2 Spike protein
ZW Tan, WV Tee, F Samsudin, E Guarnera, PJ Bond, IN Berezovsky
Structure 30 (4), 590-607. e4, 2022
232022
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Artikelen 1–20