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Kaixiang Cao
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Histone H3K4 monomethylation catalyzed by Trr and mammalian COMPASS-like proteins at enhancers is dispensable for development and viability
R Rickels, HM Herz, CC Sze, K Cao, MA Morgan, CK Collings, M Gause, ...
Nature genetics 49 (11), 1647-1653, 2017
1952017
High-resolution mapping of h1 linker histone variants in embryonic stem cells
K Cao, N Lailler, Y Zhang, A Kumar, K Uppal, Z Liu, EK Lee, H Wu, ...
PLoS genetics 9 (4), e1003417, 2013
1282013
PAF1 regulation of promoter-proximal pause release via enhancer activation
FX Chen, P Xie, CK Collings, K Cao, Y Aoi, SA Marshall, EJ Rendleman, ...
Science 357 (6357), 1294-1298, 2017
1272017
Histone h1 depletion impairs embryonic stem cell differentiation
Y Zhang, M Cooke, S Panjwani, K Cao, B Krauth, PY Ho, M Medrzycki, ...
PLoS genetics 8 (5), e1002691, 2012
1202012
Not all H3K4 methylations are created equal: Mll2/COMPASS dependency in primordial germ cell specification
D Hu, X Gao, K Cao, MA Morgan, G Mas, ER Smith, AG Volk, ET Bartom, ...
Molecular cell 65 (3), 460-475. e6, 2017
942017
Histone H1.3 Suppresses H19 Noncoding RNA Expression and Cell Growth of Ovarian Cancer Cells
M Medrzycki, Y Zhang, W Zhang, K Cao, C Pan, N Lailler, JF McDonald, ...
Cancer research 74 (22), 6463-6473, 2014
912014
Uncoupling histone H3K4 trimethylation from developmental gene expression via an equilibrium of COMPASS, Polycomb and DNA methylation
D Douillet, CC Sze, C Ryan, A Piunti, AP Shah, M Ugarenko, SA Marshall, ...
Nature genetics 52 (6), 615-625, 2020
902020
Histone H3K4 methylation-dependent and-independent functions of Set1A/COMPASS in embryonic stem cell self-renewal and differentiation
CC Sze, K Cao, CK Collings, SA Marshall, EJ Rendleman, PA Ozark, ...
Genes & development 31 (17), 1732-1737, 2017
842017
An Mll4/COMPASS-Lsd1 epigenetic axis governs enhancer function and pluripotency transition in embryonic stem cells
K Cao, CK Collings, MA Morgan, SA Marshall, EJ Rendleman, PA Ozark, ...
Science advances 4 (1), eaap8747, 2018
652018
A cryptic Tudor domain links BRWD2/PHIP to COMPASS-mediated histone H3K4 methylation
MAJ Morgan, RA Rickels, CK Collings, X He, K Cao, HM Herz, ...
Genes & development 31 (19), 2003-2014, 2017
632017
SET1A/COMPASS and shadow enhancers in the regulation of homeotic gene expression
K Cao, CK Collings, SA Marshall, MA Morgan, EJ Rendleman, L Wang, ...
Genes & development 31 (8), 787-801, 2017
532017
DOT1L-controlled cell-fate determination and transcription elongation are independent of H3K79 methylation
K Cao, M Ugarenko, PA Ozark, J Wang, SA Marshall, EJ Rendleman, ...
Proceedings of the National Academy of Sciences 117 (44), 27365-27373, 2020
472020
Coordinated regulation of cellular identity–associated H3K4me3 breadth by the COMPASS family
CC Sze, PA Ozark, K Cao, M Ugarenko, S Das, LU Wang, SA Marshall, ...
Science advances 6 (26), eaaz4764, 2020
402020
Inhibit globally, act locally: CDK7 inhibitors in cancer therapy
K Cao, A Shilatifard
Cancer cell 26 (2), 158-159, 2014
322014
Inhibition of DNA methyltransferases and histone deacetylases induces astrocytic differentiation of neural progenitors
A Majumder, SK Dhara, R Swetenburg, M Mithani, K Cao, M Medrzycki, ...
Stem cell research 11 (1), 574-586, 2013
322013
Reduction of Hox gene expression by histone H1 depletion
Y Zhang, Z Liu, M Medrzycki, K Cao, Y Fan
PloS one 7 (6), e38829, 2012
252012
Expression analysis of mammalian linker-histone subtypes
M Medrzycki, Y Zhang, K Cao, Y Fan
JoVE (Journal of Visualized Experiments), e3577, 2012
232012
A synthetic lethality screen reveals ING5 as a genetic dependency of catalytically dead Set1A/COMPASS in mouse embryonic stem cells
BK Cenik, CC Sze, CA Ryan, S Das, K Cao, D Douillet, EJ Rendleman, ...
Proceedings of the National Academy of Sciences 119 (19), e2118385119, 2022
42022
Enhancers in cancer: Genetic and epigenetic deregulation
K Cao, A Shilatifard
Encyclopedia of Cancer, 559-568, 2018
32018
Demethylase-independent roles of LSD1 in regulating enhancers and cell fate transition
C Zeng, J Chen, EW Cooke, A Subuddhi, ET Roodman, FX Chen, K Cao
Nature Communications 14 (1), 4944, 2023
22023
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