A Pym
A Pym
Africa Health Research Institute (AHRI)
Geverifieerd e-mailadres voor ahri.org - Homepage
TitelGeciteerd doorJaar
A new evolutionary scenario for the Mycobacterium tuberculosis complex
R Brosch, SV Gordon, M Marmiesse, P Brodin, C Buchrieser, K Eiglmeier, ...
Proceedings of the national academy of Sciences 99 (6), 3684-3689, 2002
17262002
The diarylquinoline TMC207 for multidrug-resistant tuberculosis
AH Diacon, A Pym, M Grobusch, R Patientia, R Rustomjee, L Page-Shipp, ...
New England Journal of Medicine 360 (23), 2397-2405, 2009
7842009
Loss of RD1 contributed to the attenuation of the live tuberculosis vaccines Mycobacterium bovis BCG and Mycobacterium microti
AS Pym, P Brodin, R Brosch, M Huerre, ST Cole
Molecular microbiology 46 (3), 709-717, 2002
7102002
Recombinant BCG exporting ESAT-6 confers enhanced protection against tuberculosis
AS Pym, P Brodin, L Majlessi, R Brosch, C Demangel, A Williams, ...
Nature medicine 9 (5), 533, 2003
6792003
Multidrug-resistant tuberculosis and culture conversion with bedaquiline
AH Diacon, A Pym, MP Grobusch, JM de los Rios, E Gotuzzo, I Vasilyeva, ...
New England Journal of Medicine 371 (8), 723-732, 2014
4482014
Four-month moxifloxacin-based regimens for drug-sensitive tuberculosis
NAJ Gillespie SH1, Crook AM, McHugh TD, Mendel CM, Meredith SK, Murray SR ...
New England Journal of Medicine 371 (17), 1577-87, 2014
4202014
Feasibility, accuracy, and clinical effect of point-of-care Xpert MTB/RIF testing for tuberculosis in primary-care settings in Africa: a multicentre, randomised, controlled trial
G Theron, L Zijenah, D Chanda, P Clowes, A Rachow, M Lesosky, W Bara, ...
The Lancet 383 (9915), 424-435, 2014
3812014
Randomized pilot trial of eight weeks of bedaquiline (TMC207) treatment for multidrug-resistant tuberculosis: long-term outcome, tolerability, and effect on emergence of drug …
AH Diacon, PR Donald, A Pym, M Grobusch, RF Patientia, R Mahanyele, ...
Antimicrobial agents and chemotherapy 56 (6), 3271-3276, 2012
3302012
Effect of katG mutations on the virulence of Mycobacterium tuberculosis and the implication for transmission in humans
AS Pym, B Saint-Joanis, ST Cole
Infection and immunity 70 (9), 4955-4960, 2002
2772002
Genomic deletions classify the Beijing/W strains as a distinct genetic lineage of Mycobacterium tuberculosis
AG Tsolaki, S Gagneux, AS Pym, BN Kreiswirth, D Van Soolingen, ...
Journal of clinical microbiology 43 (7), 3185-3191, 2005
2712005
The evolution of mycobacterial pathogenicity: clues from comparative genomics
R Brosch, AS Pym, SV Gordon, ST Cole
Trends in microbiology 9 (9), 452-458, 2001
2672001
Impact of bacterial genetics on the transmission of isoniazid-resistant Mycobacterium tuberculosis
S Gagneux, MV Burgos, K DeRiemer, A Enciso, S Munoz, PC Hopewell, ...
PLoS pathogens 2 (6), e61, 2006
2332006
Systematic genetic nomenclature for type VII secretion systems
W Bitter, ENG Houben, D Bottai, P Brodin, EJ Brown, JS Cox, ...
PLoS pathogens 5 (10), e1000507, 2009
1982009
Efficiency and safety of the combination of moxifloxacin, pretomanid (PA-824), and pyrazinamide during the first 8 weeks of antituberculosis treatment: a phase 2b, open-label …
R Dawson, AH Diacon, D Everitt, C van Niekerk, PR Donald, DA Burger, ...
The Lancet 385 (9979), 1738-1747, 2015
1742015
Evaluation of vaccines in the EU TB Vaccine Cluster using a guinea pig aerosol infection model of tuberculosis
A Williams, GJ Hatch, SO Clark, KE Gooch, KA Hatch, GA Hall, K Huygen, ...
Tuberculosis 85 (1-2), 29-38, 2005
1662005
Regulation of catalase–peroxidase (KatG) expression, isoniazid sensitivity and virulence by furA of Mycobacterium tuberculosis
AS Pym, P Domenech, N Honoré, J Song, V Deretic, ST Cole
Molecular microbiology 40 (4), 879-889, 2001
1502001
Whole-genome sequencing to establish relapse or re-infection with Mycobacterium tuberculosis: a retrospective observational study
JM Bryant, SR Harris, J Parkhill, R Dawson, AH Diacon, P van Helden, ...
The Lancet Respiratory Medicine 1 (10), 786-792, 2013
1482013
Comparative genomics of the mycobacteria
R Brosch, SV Gordon, A Pym, K Eiglmeier, T Garnier, ST Cole
International journal of medical microbiology 290 (2), 143-152, 2000
1472000
Bedaquiline in the treatment of multidrug-and extensively drug-resistant tuberculosis
AS Pym, AH Diacon, SJ Tang, F Conradie, M Danilovits, C Chuchottaworn, ...
European Respiratory Journal 47 (2), 564-574, 2016
1392016
Evolution of extensively drug-resistant tuberculosis over four decades: whole genome sequencing and dating analysis of Mycobacterium tuberculosis isolates from KwaZulu-Natal
KA Cohen, T Abeel, AM McGuire, CA Desjardins, V Munsamy, TP Shea, ...
PLoS medicine 12 (9), e1001880, 2015
1312015
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Artikelen 1–20