| Intratumor heterogeneity and branched evolution revealed by multiregion sequencing M Gerlinger, AJ Rowan, S Horswell, J Larkin, D Endesfelder, E Gronroos, ... New England journal of medicine 366 (10), 883-892, 2012 | 8510 | 2012 |
| SREBP activity is regulated by mTORC1 and contributes to Akt-dependent cell growth T Porstmann, CR Santos, B Griffiths, M Cully, M Wu, S Leevers, ... Cell metabolism 8 (3), 224-236, 2008 | 1556 | 2008 |
| Lipid metabolism in cancer CR Santos, A Schulze The FEBS journal 279 (15), 2610-2623, 2012 | 1420 | 2012 |
| Genomic architecture and evolution of clear cell renal cell carcinomas defined by multiregion sequencing M Gerlinger, S Horswell, J Larkin, AJ Rowan, MP Salm, I Varela, R Fisher, ... Nature genetics 46 (3), 225-233, 2014 | 1351 | 2014 |
| Towards Industry 4.0: an overview of European strategic roadmaps C Santos, A Mehrsai, AC Barros, M Araújo, E Ares Procedia manufacturing 13, 972-979, 2017 | 361 | 2017 |
| Functional metabolic screen identifies 6-phosphofructo-2-kinase/fructose-2, 6-biphosphatase 4 as an important regulator of prostate cancer cell survival S Ros, CR Santos, S Moco, F Baenke, G Kelly, M Howell, N Zamboni, ... Cancer discovery 2 (4), 328-343, 2012 | 223 | 2012 |
| SETD2 loss-of-function promotes renal cancer branched evolution through replication stress and impaired DNA repair N Kanu, E Grönroos, P Martinez, RA Burrell, X Yi Goh, J Bartkova, ... Oncogene 34 (46), 5699-5708, 2015 | 183 | 2015 |
| Systematic evaluation of the prognostic impact and intratumour heterogeneity of clear cell renal cell carcinoma biomarkers S Gulati, P Martinez, T Joshi, NJ Birkbak, CR Santos, AJ Rowan, ... European urology 66 (5), 936-948, 2014 | 172 | 2014 |
| Human vaccinia-related kinase 1 (VRK1) activates the ATF2 transcriptional activity by novel phosphorylation on Thr-73 and Ser-62 and cooperates with JNK A Sevilla, CR Santos, FM Vega, PA Lazo Journal of Biological Chemistry 279 (26), 27458-27465, 2004 | 139 | 2004 |
| Genome‐wide RNA interference analysis of renal carcinoma survival regulators identifies MCT4 as a Warburg effect metabolic target M Gerlinger, CR Santos, B Spencer‐Dene, P Martinez, D Endesfelder, ... The Journal of pathology 227 (2), 146-156, 2012 | 138 | 2012 |
| c-Jun phosphorylation by the human vaccinia-related kinase 1 (VRK1) and its cooperation with the N-terminal kinase of c-Jun (JNK) A Sevilla, CR Santos, R Barcia, FM Vega, PA Lazo Oncogene 23 (55), 8950-8958, 2004 | 126 | 2004 |
| A new player in the orchestra of cell growth: SREBP activity is regulated by mTORC1 and contributes to the regulation of cell and organ size T Porstmann, CR Santos, C Lewis, B Griffiths, A Schulze Biochemical Society Transactions 37 (1), 278-283, 2009 | 101 | 2009 |
| VRK1 signaling pathway in the context of the proliferation phenotype in head and neck squamous cell carcinoma CR Santos, M Rodríguez-Pinilla, FM Vega, JL Rodríguez-Peralto, ... Molecular cancer research 4 (3), 177-185, 2006 | 96 | 2006 |
| Regulation of the SREBP transcription factors by mTORC1 CA Lewis, B Griffiths, CR Santos, M Pende, A Schulze Biochemical Society transactions 39 (2), 495-499, 2011 | 92 | 2011 |
| Modulation of interleukin-1 transcriptional response by the interaction between VRK2 and the JIP1 scaffold protein S Blanco, M Sanz-García, CR Santos, PA Lazo PloS one 3 (2), e1660, 2008 | 81 | 2008 |
| Vaccinia-related kinase 2 modulates the stress response to hypoxia mediated by TAK1 S Blanco, C Santos, PA Lazo Molecular and cellular biology 27 (20), 7273-7283, 2007 | 77 | 2007 |
| The vaccinia virus B1R kinase induces p53 downregulation by an Mdm2-dependent mechanism CR Santos, FM Vega, S Blanco, R Barcia, PA Lazo Virology 328 (2), 254-265, 2004 | 61 | 2004 |
| Interference with p53 functions in human viral infections, a target for novel antiviral strategies? PA Lazo, CR Santos Reviews in medical virology 21 (5), 285-300, 2011 | 44 | 2011 |
| Tumour-suppression function of KLF12 through regulation of anoikis N Godin-Heymann, S Brabetz, MM Murillo, M Saponaro, CR Santos, ... Oncogene 35 (25), 3324-3334, 2016 | 40 | 2016 |
| Vaccinia virus B1R kinase interacts with JIP1 and modulates c-Jun-dependent signaling CR Santos, S Blanco, A Sevilla, PA Lazo Journal of virology 80 (15), 7667-7675, 2006 | 37 | 2006 |
Prof Marco GerlingerBarts Cancer Institute, London, UKGeverifieerd e-mailadres voor qmul.ac.uk
