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Gregory Z. Ferl
Gregory Z. Ferl
Distinguished Scientist, Genentech, Inc.
Verified email at gene.com - Homepage
Title
Cited by
Cited by
Year
A predictive model of therapeutic monoclonal antibody dynamics and regulation by the neonatal Fc receptor (FcRn)
GZ Ferl, AM Wu, JJ DiStefano
Annals of biomedical engineering 33 (11), 1640-1652, 2005
1722005
Evaluation of [18F]gefitinib as a molecular imaging probe for the assessment of the epidermal growth factor receptor status in malignant tumors
H Su, Y Seimbille, GZ Ferl, C Bodenstein, B Fueger, KJ Kim, YT Hsu, ...
European journal of nuclear medicine and molecular imaging 35, 1089-1099, 2008
1342008
Phosphoinositide 3-kinase and Bruton's tyrosine kinase regulate overlapping sets of genes in B lymphocytes
DA Fruman, GZ Ferl, SS An, AC Donahue, AB Satterthwaite, ON Witte
Proceedings of the National Academy of Sciences 99 (1), 359-364, 2002
1032002
Estimation of the 18F-FDG input function in mice by use of dynamic small-animal PET and minimal blood sample data
GZ Ferl, X Zhang, HM Wu, SC Huang
Journal of Nuclear Medicine 48 (12), 2037-2045, 2007
852007
A two-tiered physiologically based model for dually labeled single-chain Fv-Fc antibody fragments
GZ Ferl, V Kenanova, AM Wu, JJ DiStefano III
Molecular cancer therapeutics 5 (6), 1550-1558, 2006
702006
Physiologically based pharmacokinetic models of small molecules and therapeutic antibodies: a mini‐review on fundamental concepts and applications
GZ Ferl, FP Theil, H Wong
Biopharmaceutics & Drug Disposition 37 (2), 75-92, 2016
462016
Derivation of a compartmental model for quantifying 64Cu-DOTA-RGD kinetics in tumor-bearing mice
GZ Ferl, RA Dumont, IJ Hildebrandt, A Armijo, R Haubner, G Reischl, ...
Journal of Nuclear Medicine 50 (2), 250-258, 2009
432009
An automated method for nonparametric kinetic analysis of clinical DCE‐MRI data: application to glioblastoma treated with bevacizumab
GZ Ferl, L Xu, M Friesenhahn, LJ Bernstein, DP Barboriak, RE Port
Magnetic Resonance in Medicine 63 (5), 1366-1375, 2010
412010
Effects of anti-VEGF on predicted antibody biodistribution: roles of vascular volume, interstitial volume, and blood flow
CA Boswell, GZ Ferl, EE Mundo, D Bumbaca, MG Schweiger, FP Theil, ...
PloS one 6 (3), e17874, 2011
352011
A preclinical population pharmacokinetic model for anti‐CD20/CD3 T‐cell‐dependent bispecific antibodies
GZ Ferl, A Reyes, LL Sun, M Cheu, A Oldendorp, S Ramanujan, ...
Clinical and Translational Science 11 (3), 296-304, 2018
262018
Development and evaluation of a novel method for preclinical measurement of tissue vascular volume
CA Boswell, GZ Ferl, EE Mundo, MG Schweiger, J Marik, MP Reich, ...
Molecular Pharmaceutics, 2010
232010
A phosphorylation site in Bruton's tyrosine kinase selectively regulates B cell calcium signaling efficiency by altering phospholipase C-γ activation
S Guo, GZ Ferl, R Deora, M Riedinger, S Yin, JL Kerwin, JA Loo, ON Witte
Proceedings of the National Academy of Sciences 101 (39), 14180-14185, 2004
222004
Tissue physiology of cynomolgus monkeys: cross-species comparison and implications for translational pharmacology
D Mandikian, I Figueroa, A Oldendorp, H Rafidi, S Ulufatu, MG Schweiger, ...
The AAPS Journal 20, 1-13, 2018
212018
VCAM-1 density and tumor perfusion predict T-cell infiltration and treatment response in preclinical models
J Riegler, H Gill, A Ogasawara, M Hedehus, V Javinal, J Oeh, GZ Ferl, ...
Neoplasia 21 (10), 1036-1050, 2019
202019
Quantification of antiangiogenic and antivascular drug activity by kinetic analysis of DCE‐MRI data
GZ Ferl, RE Port
Clinical Pharmacology & Therapeutics 92 (1), 118-124, 2012
172012
Treatment planning in PRRT based on simulated PET data and a PBPK model
D Hardiansyah, W Guo, AA Attarwala, P Kletting, FM Mottaghy, G Glatting
Nuklearmedizin-NuclearMedicine 56 (01), 23-30, 2017
142017
DATforDCEMRI: an R package for deconvolution analysis and visualization of DCE-MRI data
GZ Ferl
Journal of Statistical Software 44, 1-18, 2011
14*2011
Extending the utility of gene profiling data by bridging microarray platforms
GZ Ferl, JM Timmerman, ON Witte
Proceedings of the National Academy of Sciences 100 (19), 10585-10587, 2003
142003
Biodistribution and efficacy of an anti-TENB2 antibody-drug conjugate in a patient-derived model of prostate cancer
CA Boswell, DB Yadav, EE Mundo, SF Yu, JA Lacap, ...
Oncotarget 10 (58), 6234, 2019
132019
Mixed‐effects modeling of clinical DCE‐MRI data: application to colorectal liver metastases treated with bevacizumab
GZ Ferl, JPB O'Connor, GJM Parker, RAD Carano, SJ Acharya, ...
Journal of Magnetic Resonance Imaging 41 (1), 132-141, 2015
132015
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