A predictive model of therapeutic monoclonal antibody dynamics and regulation by the neonatal Fc receptor (FcRn) GZ Ferl, AM Wu, JJ DiStefano Annals of biomedical engineering 33 (11), 1640-1652, 2005 | 172 | 2005 |
Evaluation of [18F]gefitinib as a molecular imaging probe for the assessment of the epidermal growth factor receptor status in malignant tumors H Su, Y Seimbille, GZ Ferl, C Bodenstein, B Fueger, KJ Kim, YT Hsu, ... European journal of nuclear medicine and molecular imaging 35, 1089-1099, 2008 | 134 | 2008 |
Phosphoinositide 3-kinase and Bruton's tyrosine kinase regulate overlapping sets of genes in B lymphocytes DA Fruman, GZ Ferl, SS An, AC Donahue, AB Satterthwaite, ON Witte Proceedings of the National Academy of Sciences 99 (1), 359-364, 2002 | 103 | 2002 |
Estimation of the 18F-FDG input function in mice by use of dynamic small-animal PET and minimal blood sample data GZ Ferl, X Zhang, HM Wu, SC Huang Journal of Nuclear Medicine 48 (12), 2037-2045, 2007 | 85 | 2007 |
A two-tiered physiologically based model for dually labeled single-chain Fv-Fc antibody fragments GZ Ferl, V Kenanova, AM Wu, JJ DiStefano III Molecular cancer therapeutics 5 (6), 1550-1558, 2006 | 70 | 2006 |
Physiologically based pharmacokinetic models of small molecules and therapeutic antibodies: a mini‐review on fundamental concepts and applications GZ Ferl, FP Theil, H Wong Biopharmaceutics & Drug Disposition 37 (2), 75-92, 2016 | 46 | 2016 |
Derivation of a compartmental model for quantifying 64Cu-DOTA-RGD kinetics in tumor-bearing mice GZ Ferl, RA Dumont, IJ Hildebrandt, A Armijo, R Haubner, G Reischl, ... Journal of Nuclear Medicine 50 (2), 250-258, 2009 | 43 | 2009 |
An automated method for nonparametric kinetic analysis of clinical DCE‐MRI data: application to glioblastoma treated with bevacizumab GZ Ferl, L Xu, M Friesenhahn, LJ Bernstein, DP Barboriak, RE Port Magnetic Resonance in Medicine 63 (5), 1366-1375, 2010 | 41 | 2010 |
Effects of anti-VEGF on predicted antibody biodistribution: roles of vascular volume, interstitial volume, and blood flow CA Boswell, GZ Ferl, EE Mundo, D Bumbaca, MG Schweiger, FP Theil, ... PloS one 6 (3), e17874, 2011 | 35 | 2011 |
A preclinical population pharmacokinetic model for anti‐CD20/CD3 T‐cell‐dependent bispecific antibodies GZ Ferl, A Reyes, LL Sun, M Cheu, A Oldendorp, S Ramanujan, ... Clinical and Translational Science 11 (3), 296-304, 2018 | 26 | 2018 |
Development and evaluation of a novel method for preclinical measurement of tissue vascular volume CA Boswell, GZ Ferl, EE Mundo, MG Schweiger, J Marik, MP Reich, ... Molecular Pharmaceutics, 2010 | 23 | 2010 |
A phosphorylation site in Bruton's tyrosine kinase selectively regulates B cell calcium signaling efficiency by altering phospholipase C-γ activation S Guo, GZ Ferl, R Deora, M Riedinger, S Yin, JL Kerwin, JA Loo, ON Witte Proceedings of the National Academy of Sciences 101 (39), 14180-14185, 2004 | 22 | 2004 |
Tissue physiology of cynomolgus monkeys: cross-species comparison and implications for translational pharmacology D Mandikian, I Figueroa, A Oldendorp, H Rafidi, S Ulufatu, MG Schweiger, ... The AAPS Journal 20, 1-13, 2018 | 21 | 2018 |
VCAM-1 density and tumor perfusion predict T-cell infiltration and treatment response in preclinical models J Riegler, H Gill, A Ogasawara, M Hedehus, V Javinal, J Oeh, GZ Ferl, ... Neoplasia 21 (10), 1036-1050, 2019 | 20 | 2019 |
Quantification of antiangiogenic and antivascular drug activity by kinetic analysis of DCE‐MRI data GZ Ferl, RE Port Clinical Pharmacology & Therapeutics 92 (1), 118-124, 2012 | 17 | 2012 |
Treatment planning in PRRT based on simulated PET data and a PBPK model D Hardiansyah, W Guo, AA Attarwala, P Kletting, FM Mottaghy, G Glatting Nuklearmedizin-NuclearMedicine 56 (01), 23-30, 2017 | 14 | 2017 |
DATforDCEMRI: an R package for deconvolution analysis and visualization of DCE-MRI data GZ Ferl Journal of Statistical Software 44, 1-18, 2011 | 14* | 2011 |
Extending the utility of gene profiling data by bridging microarray platforms GZ Ferl, JM Timmerman, ON Witte Proceedings of the National Academy of Sciences 100 (19), 10585-10587, 2003 | 14 | 2003 |
Biodistribution and efficacy of an anti-TENB2 antibody-drug conjugate in a patient-derived model of prostate cancer CA Boswell, DB Yadav, EE Mundo, SF Yu, JA Lacap, ... Oncotarget 10 (58), 6234, 2019 | 13 | 2019 |
Mixed‐effects modeling of clinical DCE‐MRI data: application to colorectal liver metastases treated with bevacizumab GZ Ferl, JPB O'Connor, GJM Parker, RAD Carano, SJ Acharya, ... Journal of Magnetic Resonance Imaging 41 (1), 132-141, 2015 | 13 | 2015 |