| Nitroheterocyclic compounds are more efficacious than CYP51 inhibitors against Trypanosoma cruzi: implications for Chagas disease drug discovery and … CB Moraes, MA Giardini, H Kim, CH Franco, AM Araujo-Junior, ... Scientific reports 4 (1), 4703, 2014 | 221 | 2014 |
| Bacteria from Antarctic environments: diversity and detection of antimicrobial, antiproliferative, and antiparasitic activities TR Silva, AWF Duarte, MRZ Passarini, ALTG Ruiz, CH Franco, ... Polar Biology 41, 1505-1519, 2018 | 51 | 2018 |
| A comparative study of warheads for design of cysteine protease inhibitors DG Silva, JFR Ribeiro, D De Vita, L Cianni, CH Franco, LH Freitas-Junior, ... Bioorganic & medicinal chemistry letters 27 (22), 5031-5035, 2017 | 42 | 2017 |
| Drug discovery for Chagas disease: impact of different host cell lines on assay performance and hit compound selection CH Franco, LM Alcântara, E Chatelain, L Freitas-Junior, CB Moraes Tropical Medicine and Infectious Disease 4 (2), 82, 2019 | 39 | 2019 |
| Aryl thiosemicarbazones for the treatment of trypanosomatidic infections P Linciano, CB Moraes, LM Alcantara, CH Franco, B Pascoalino, ... European Journal of Medicinal Chemistry 146, 423-434, 2018 | 37 | 2018 |
| Design, synthesis and antitrypanosomal activity of some nitrofurazone 1, 2, 4-triazolic bioisosteric analogues FT Silva, CH Franco, DC Favaro, LH Freitas-Junior, CB Moraes, ... European Journal of Medicinal Chemistry 121, 553-560, 2016 | 34 | 2016 |
| Chemosensitization potential of P-glycoprotein inhibitors in malaria parasites LM Alcantara, J Kim, CB Moraes, CH Franco, KD Franzoi, S Lee, ... Experimental parasitology 134 (2), 235-243, 2013 | 28 | 2013 |
| Enhancement of benzothiazoles as pteridine reductase-1 inhibitors for the treatment of trypanosomatidic infections P Linciano, C Pozzi, LD Iacono, F di Pisa, G Landi, A Bonucci, S Gul, ... Journal of Medicinal Chemistry 62 (8), 3989-4012, 2019 | 27 | 2019 |
| Discovery of new potent hits against intracellular Trypanosoma cruzi by QSAR-based virtual screening CC Melo-Filho, RC Braga, EN Muratov, CH Franco, CB Moraes, ... European journal of medicinal chemistry 163, 649-659, 2019 | 26 | 2019 |
| Methoxylated 2'-hydroxychalcones as antiparasitic hit compounds C Borsari, N Santarem, J Torrado, AI Olías, MJ Corral, C Baptista, S Gul, ... European Journal of Medicinal Chemistry 126, 1129-1135, 2017 | 26 | 2017 |
| Novel drug discovery for Chagas disease CB Moraes, CH Franco Expert opinion on drug discovery 11 (5), 447-455, 2016 | 25 | 2016 |
| Discovery of a benzothiophene-flavonol halting miltefosine and antimonial drug resistance in Leishmania parasites through the application of medicinal chemistry, screening and … C Borsari, MD Jiménez-Antón, J Eick, E Bifeld, JJ Torrado, ... European Journal of Medicinal Chemistry 183, 111676, 2019 | 22 | 2019 |
| Synthesis and structure-activity relationship of nitrile-based cruzain inhibitors incorporating a trifluoroethylamine-based P2 amide replacement JC Gomes, L Cianni, J Ribeiro, F dos Reis Rocho, SCM Silva, PHJ Batista, ... Bioorganic & Medicinal Chemistry 27 (22), 115083, 2019 | 21 | 2019 |
| Highly improved antiparasitic activity after introduction of an N-benzylimidazole moiety on protein farnesyltransferase inhibitors D Bosc, E Mouray, S Cojean, CH Franco, PM Loiseau, LH Freitas-Junior, ... European journal of medicinal chemistry 109, 173-186, 2016 | 19 | 2016 |
| Investigating the structure-activity relationships of N’-[(5-nitrofuran-2-yl) methylene] substituted hydrazides against Trypanosoma cruzi to design novel active compounds F Palace-Berl, KFM Pasqualoto, B Zingales, CB Moraes, M Bury, ... European Journal of Medicinal Chemistry 144, 29-40, 2018 | 18 | 2018 |
| Mutagenic potential of lettuce grown from irradiated seeds CH Franco, VHM dos Santos, LP Silva, V Arthur, RMG Silva Scientia Horticulturae 182, 27-30, 2015 | 16 | 2015 |
| Novel structural CYP51 mutation in Trypanosoma cruzi associated with multidrug resistance to CYP51 inhibitors and reduced infectivity CH Franco, DC Warhurst, T Bhattacharyya, HYA Au, H Le, MA Giardini, ... International Journal for Parasitology: Drugs and Drug Resistance 13, 107-120, 2020 | 10 | 2020 |
| Prospecting and identifying Phyllanthus amarus lignans with antileishmanial and antitrypanosomal activity GG Conrado, N Grazzia, S Adriana da Silva, CH Franco, CB Moraes, ... Planta Medica 86 (11), 782-789, 2020 | 10 | 2020 |
| In Vitro Anti-Trypanosoma cruzi Activity of Halophytes from Southern Portugal Reloaded: A Special Focus on Sea Fennel (Crithmum maritimum L.) CG Pereira, CB Moraes, CH Franco, C Feltrin, R Grougnet, EG Barbosa, ... Plants 10 (11), 2235, 2021 | 9 | 2021 |
| Identification of inhibitors to trypanosoma cruzi sirtuins based on compounds developed to human enzymes TM Bastos, MBP Soares, CH Franco, L Alcântara, L Antonini, M Sabatino, ... International Journal of Molecular Sciences 21 (10), 2020 | 9 | 2020 |
Carolina Borsoi MoraesDepartment of Clinical and Toxicological Analyses, School of Pharmaceutical Sciences, University ofVerified email at usp.br
