| Immune-responsive gene 1 protein links metabolism to immunity by catalyzing itaconic acid production A Michelucci, T Cordes, J Ghelfi, A Pailot, N Reiling, O Goldmann, T Binz, ... Proceedings of the National Academy of Sciences 110 (19), 7820-7825, 2013 | 989 | 2013 |
| Characterization of the microglial phenotype under specific pro-inflammatory and anti-inflammatory conditions: effects of oligomeric and fibrillar amyloid-β A Michelucci, T Heurtaux, L Grandbarbe, E Morga, P Heuschling Journal of neuroimmunology 210 (1-2), 3-12, 2009 | 489 | 2009 |
| Stem cell-associated heterogeneity in Glioblastoma results from intrinsic tumor plasticity shaped by the microenvironment A Dirkse, A Golebiewska, T Buder, PV Nazarov, A Muller, S Poovathingal, ... Nature communications 10 (1), 1787, 2019 | 457 | 2019 |
| Immunoresponsive gene 1 and itaconate inhibit succinate dehydrogenase to modulate intracellular succinate levels T Cordes, M Wallace, A Michelucci, AS Divakaruni, SC Sapcariu, C Sousa, ... Journal of Biological Chemistry 291 (27), 14274-14284, 2016 | 430 | 2016 |
| The itaconate pathway is a central regulatory node linking innate immune tolerance and trained immunity J Domínguez-Andrés, B Novakovic, Y Li, BP Scicluna, MS Gresnigt, ... Cell metabolism 29 (1), 211-220. e5, 2019 | 280 | 2019 |
| Single‐cell transcriptomics reveals distinct inflammation‐induced microglia signatures C Sousa, A Golebiewska, SK Poovathingal, T Kaoma, Y Pires‐Afonso, ... EMBO reports 19 (11), e46171, 2018 | 236 | 2018 |
| Itaconic acid: the surprising role of an industrial compound as a mammalian antimicrobial metabolite T Cordes, A Michelucci, K Hiller Annual review of nutrition 35, 451-473, 2015 | 179 | 2015 |
| Cellular and molecular characterization of microglia: a unique immune cell population C Sousa, K Biber, A Michelucci Frontiers in immunology 8, 245768, 2017 | 176 | 2017 |
| Notch signaling modulates the activation of microglial cells L Grandbarbe, A Michelucci, T Heurtaux, K Hemmer, E Morga, ... Glia 55 (15), 1519-1530, 2007 | 121 | 2007 |
| Patient-derived organoids and orthotopic xenografts of primary and recurrent gliomas represent relevant patient avatars for precision oncology A Golebiewska, AC Hau, A Oudin, D Stieber, YA Yabo, V Baus, ... Acta Neuropathologica 140, 919-949, 2020 | 88 | 2020 |
| Gene Regulatory Network Inference of Immunoresponsive Gene 1 (IRG1) Identifies Interferon Regulatory Factor 1 (IRF1) as Its Transcriptional Regulator in … A Tallam, TM Perumal, PM Antony, C Jäger, JV Fritz, L Vallar, R Balling, ... PLoS One 11 (2), e0149050, 2016 | 81 | 2016 |
| IL-33-induced metabolic reprogramming controls the differentiation of alternatively activated macrophages and the resolution of inflammation M Faas, N Ipseiz, J Ackermann, S Culemann, A Grüneboom, F Schröder, ... Immunity 54 (11), 2531-2546. e5, 2021 | 80 | 2021 |
| Inflammation promotes a conversion of astrocytes into neural progenitor cells via NF-κB activation S Gabel, E Koncina, G Dorban, T Heurtaux, C Birck, E Glaab, ... Molecular neurobiology 53, 5041-5055, 2016 | 75 | 2016 |
| Microglial activation depends on beta‐amyloid conformation: role of the formylpeptide receptor 2 T Heurtaux, A Michelucci, S Losciuto, C Gallotti, P Felten, G Dorban, ... Journal of neurochemistry 114 (2), 576-586, 2010 | 73 | 2010 |
| Jagged1 regulates the activation of astrocytes via modulation of NFκB and JAK/STAT/SOCS pathways E Morga, L Mouad‐Amazzal, P Felten, T Heurtaux, M Moro, A Michelucci, ... Glia 57 (16), 1741-1753, 2009 | 60 | 2009 |
| Revealing and harnessing tumour-associated microglia/macrophage heterogeneity in glioblastoma Y Pires-Afonso, SP Niclou, A Michelucci International journal of molecular sciences 21 (3), 689, 2020 | 59 | 2020 |
| Loss of DJ-1 impairs antioxidant response by altered glutamine and serine metabolism J Meiser, S Delcambre, A Wegner, C Jäger, J Ghelfi, AF d'Herouel, ... Neurobiology of disease 89, 112-125, 2016 | 57 | 2016 |
| Citraconate inhibits ACOD1 (IRG1) catalysis, reduces interferon responses and oxidative stress, and modulates inflammation and cell metabolism F Chen, WAM Elgaher, M Winterhoff, K Büssow, FH Waqas, E Graner, ... Nature Metabolism 4 (5), 534-546, 2022 | 55 | 2022 |
| Itaconate and derivatives reduce interferon responses and inflammation in influenza A virus infection A Sohail, AA Iqbal, N Sahini, F Chen, M Tantawy, SFH Waqas, ... PLoS pathogens 18 (1), e1010219, 2022 | 49 | 2022 |
| Neurodegeneration and neuroinflammation are linked, but independent of alpha‐synuclein inclusions, in a seeding/spreading mouse model of Parkinson's disease P Garcia, W Jürgens‐Wemheuer, O Uriarte Huarte, A Michelucci, ... Glia 70 (5), 935-960, 2022 | 44 | 2022 |
Simone P. NiclouUniversity of LuxembourgGeverifieerd e-mailadres voor lih.lu
