| On the temperature dependence of enzyme-catalyzed rates VL Arcus, EJ Prentice, JK Hobbs, AJ Mulholland, MW Van der Kamp, ... Biochemistry 55 (12), 1681-1688, 2016 | 283 | 2016 |
| Thermodynamic theory explains the temperature optima of soil microbial processes and high Q10 values at low temperatures LA Schipper, JK Hobbs, S Rutledge, VL Arcus Global change biology 20 (11), 3578-3586, 2014 | 221 | 2014 |
| Change in heat capacity for enzyme catalysis determines temperature dependence of enzyme catalyzed rates JK Hobbs, W Jiao, AD Easter, EJ Parker, LA Schipper, VL Arcus ACS chemical biology 8 (11), 2388-2393, 2013 | 206 | 2013 |
| Consequences of daptomycin-mediated membrane damage in Staphylococcus aureus JK Hobbs, K Miller, AJ O’Neill, I Chopra Journal of Antimicrobial Chemotherapy 62 (5), 1003-1008, 2008 | 166 | 2008 |
| On the Origin and Evolution of Thermophily: Reconstruction of Functional Precambrian Enzymes from Ancestors of Bacillus JK Hobbs, C Shepherd, DJ Saul, NJ Demetras, S Haaning, CR Monk, ... Molecular biology and evolution 29 (2), 825-835, 2012 | 112 | 2012 |
| XF-73, a novel antistaphylococcal membrane-active agent with rapid bactericidal activity N Ooi, K Miller, J Hobbs, W Rhys-Williams, W Love, I Chopra Journal of antimicrobial chemotherapy 64 (4), 735-740, 2009 | 108 | 2009 |
| (p) ppGpp and the stringent response: an emerging threat to antibiotic therapy JK Hobbs, AB Boraston ACS infectious diseases 5 (9), 1505-1517, 2019 | 87 | 2019 |
| KdgF, the missing link in the microbial metabolism of uronate sugars from pectin and alginate JK Hobbs, SM Lee, M Robb, F Hof, C Barr, KT Abe, JH Hehemann, ... Proceedings of the National Academy of Sciences 113 (22), 6188-6193, 2016 | 75 | 2016 |
| Molecular Characterization of N-glycan Degradation and Transport in Streptococcus pneumoniae and Its Contribution to Virulence M Robb, JK Hobbs, SA Woodiga, S Shapiro-Ward, MDL Suits, ... PLoS pathogens 13 (1), e1006090, 2017 | 70 | 2017 |
| Insights into the κ/ι-carrageenan metabolism pathway of some marine Pseudoalteromonas species AG Hettle, JK Hobbs, B Pluvinage, C Vickers, KT Abe, O Salama-Alber, ... Communications biology 2 (1), 474, 2019 | 51 | 2019 |
| Toward more accurate ancestral protein genotype–phenotype reconstructions with the use of species tree-aware gene trees M Groussin, JK Hobbs, GJ Szöllősi, S Gribaldo, VL Arcus, M Gouy Molecular Biology and Evolution 32 (1), 13-22, 2015 | 49 | 2015 |
| Glycan‐metabolizing enzymes in microbe–host interactions: the Streptococcus pneumoniae paradigm JK Hobbs, B Pluvinage, AB Boraston FEBS letters 592 (23), 3865-3897, 2018 | 43 | 2018 |
| Evaluation of linezolid for the treatment of Clostridium difficile infection caused by epidemic strains using an in vitro human gut model SD Baines, AR Noel, GS Huscroft, SL Todhunter, R O'Connor, JK Hobbs, ... Journal of antimicrobial chemotherapy 66 (7), 1537-1546, 2011 | 38 | 2011 |
| Biochemical reconstruction of a metabolic pathway from a marine bacterium reveals its mechanism of pectin depolymerization JK Hobbs, AG Hettle, C Vickers, AB Boraston Applied and Environmental Microbiology 85 (1), e02114-18, 2019 | 26 | 2019 |
| A second β-hexosaminidase encoded in the Streptococcus pneumoniae genome provides an expanded biochemical ability to degrade host glycans M Robb, CS Robb, MA Higgins, JK Hobbs, JC Paton, AB Boraston Journal of Biological Chemistry 290 (52), 30888-30900, 2015 | 24 | 2015 |
| Metabolism of a hybrid algal galactan by members of the human gut microbiome CS Robb, JK Hobbs, B Pluvinage, G Reintjes, L Klassen, S Monteith, ... Nature chemical biology 18 (5), 501-510, 2022 | 23 | 2022 |
| Reconstructed ancestral enzymes impose a fitness cost upon modern bacteria despite exhibiting favourable biochemical properties JK Hobbs, EJ Prentice, M Groussin, VL Arcus Journal of molecular evolution 81, 110-120, 2015 | 22 | 2015 |
| Clinical Mutations That Partially Activate the Stringent Response Confer Multidrug Tolerance in Staphylococcus aureus D Bryson, AG Hettle, AB Boraston, JK Hobbs Antimicrobial Agents and Chemotherapy 64 (3), 10.1128/aac. 02103-19, 2020 | 19 | 2020 |
| Two complementary α-fucosidases from Streptococcus pneumoniae promote complete degradation of host-derived carbohydrate antigens JK Hobbs, B Pluvinage, M Robb, SP Smith, AB Boraston Journal of Biological Chemistry 294 (34), 12670-12682, 2019 | 19 | 2019 |
| Functional analyses of resurrected and contemporary enzymes illuminate an evolutionary path for the emergence of exolysis in polysaccharide lyase family 2 R McLean, JK Hobbs, MD Suits, ST Tuomivaara, DR Jones, AB Boraston, ... Journal of Biological Chemistry 290 (35), 21231-21243, 2015 | 17 | 2015 |
