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Siroon Bekkering
Siroon Bekkering
Radboudumc, MCRI
Geverifieerd e-mailadres voor radboudumc.nl
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Glutaminolysis and fumarate accumulation integrate immunometabolic and epigenetic programs in trained immunity
RJW Arts, B Novakovic, R Ter Horst, A Carvalho, S Bekkering, ...
Cell metabolism 24 (6), 807-819, 2016
6892016
Metabolic induction of trained immunity through the mevalonate pathway
S Bekkering, RJW Arts, B Novakovic, I Kourtzelis, CDCC van der Heijden, ...
Cell 172 (1), 135-146. e9, 2018
5892018
Oxidized low-density lipoprotein induces long-term proinflammatory cytokine production and foam cell formation via epigenetic reprogramming of monocytes
S Bekkering, J Quintin, LAB Joosten, JWM van der Meer, MG Netea, ...
Arteriosclerosis, thrombosis, and vascular biology 34 (8), 1731-1738, 2014
5612014
Oxidized phospholipids on lipoprotein (a) elicit arterial wall inflammation and an inflammatory monocyte response in humans
FM van der Valk, S Bekkering, J Kroon, C Yeang, J Van den Bossche, ...
Circulation 134 (8), 611-624, 2016
4922016
Trained immunity, tolerance, priming and differentiation: distinct immunological processes
M Divangahi, P Aaby, SA Khader, LB Barreiro, S Bekkering, T Chavakis, ...
Nature immunology 22 (1), 2-6, 2021
3542021
In Vitro Experimental Model of Trained Innate Immunity in Human Primary Monocytes
S Bekkering, BA Blok, LAB Joosten, NP Riksen, R van Crevel, MG Netea
Clinical and Vaccine Immunology 23 (12), 926-933, 2016
2902016
Innate immune cell activation and epigenetic remodeling in symptomatic and asymptomatic atherosclerosis in humans in vivo
S Bekkering, I van den Munckhof, T Nielen, E Lamfers, C Dinarello, ...
Atherosclerosis 254, 228-236, 2016
1942016
Trained immunity: reprogramming innate immunity in health and disease
S Bekkering, J Domínguez-Andrés, LAB Joosten, NP Riksen, MG Netea
Annual review of immunology 39, 667-693, 2021
1782021
Joosten LAB, van der Meer JWM, Netea MG, Riksen NP. Oxidized low-density lipoprotein induces long-term proinflammatory cytokine production and foam cell formation via …
S Bekkering, J Quintin
Arterioscler Thromb Vasc Biol 34 (8), 1731-8, 2014
1302014
Trained innate immunity as a novel mechanism linking infection and the development of atherosclerosis
J Leentjens, S Bekkering, LAB Joosten, MG Netea, DP Burgner, ...
Circulation research 122 (5), 664-669, 2018
1172018
Remnant cholesterol elicits arterial wall inflammation and a multilevel cellular immune response in humans
SJ Bernelot Moens, SL Verweij, JG Schnitzler, LCA Stiekema, M Bos, ...
Arteriosclerosis, thrombosis, and vascular biology 37 (5), 969-975, 2017
1132017
Treatment with statins does not revert trained immunity in patients with familial hypercholesterolemia
S Bekkering, LCA Stiekema, SB Moens, SL Verweij, B Novakovic, ...
Cell metabolism 30 (1), 1-2, 2019
1112019
Effects of oral butyrate supplementation on inflammatory potential of circulating peripheral blood mononuclear cells in healthy and obese males
MCP Cleophas, JM Ratter, S Bekkering, J Quintin, K Schraa, ES Stroes, ...
Scientific reports 9 (1), 775, 2019
1072019
Long-term activation of the innate immune system in atherosclerosis
A Christ, S Bekkering, E Latz, NP Riksen
Seminars in Immunology 28 (4), 384-393, 2016
952016
Plasma cholesteryl ester transfer protein is predominantly derived from Kupffer cells
Y Wang, S van der Tuin, N Tjeerdema, AD van Dam, SS Rensen, ...
Hepatology 62 (6), 1710-1722, 2015
862015
Diabetes and overweight/obesity are independent, nonadditive risk factors for in-hospital severity of COVID-19: an international, multicenter retrospective meta-analysis
DK Longmore, JE Miller, S Bekkering, C Saner, E Mifsud, Y Zhu, R Saffery, ...
Diabetes Care 44 (6), 1281-1290, 2021
802021
Rewiring of glucose metabolism defines trained immunity induced by oxidized low-density lipoprotein
ST Keating, L Groh, K Thiem, S Bekkering, Y Li, V Matzaraki, ...
Journal of Molecular Medicine 98, 819-831, 2020
802020
The epigenetic memory of monocytes and macrophages as a novel drug target in atherosclerosis
S Bekkering, LAB Joosten, JWM van der Meer, MG Netea, NP Riksen
Clinical therapeutics 37 (4), 914-923, 2015
782015
Trained innate immunity and atherosclerosis
S Bekkering, LAB Joosten, JWM van der Meer, MG Netea, NP Riksen
Current opinion in lipidology 24 (6), 487-492, 2013
762013
Oral butyrate does not affect innate immunity and islet autoimmunity in individuals with longstanding type 1 diabetes: a randomised controlled trial
PF de Groot, T Nikolic, S Imangaliyev, S Bekkering, G Duinkerken, ...
Diabetologia 63, 597-610, 2020
702020
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Artikelen 1–20