Molybdenum-mediated carbonylation of aryl halides with nucleophiles using microwave irradiation B Roberts, D Liptrot, L Alcaraz, T Luker, MJ Stocks Organic Letters 12 (19), 4280-4283, 2010 | 123 | 2010 |
Total synthesis of desoxoprosophylline: application of a lactam-derived enol triflate to natural product synthesis T Luker, H Hiemstra, WN Speckamp The Journal of Organic Chemistry 62 (11), 3592-3596, 1997 | 88 | 1997 |
Palladium catalysed amination of electron deficient halothiophenes TJ Luker, HG Beaton, M Whiting, A Mete, DR Cheshire Tetrahedron Letters 41 (40), 7731-7735, 2000 | 69 | 2000 |
Synthesis and further reactivity of functionalized lactam-derived enol triflates T Luker, H Hiemstra, WN Speckamp The Journal of Organic Chemistry 62 (23), 8131-8140, 1997 | 69 | 1997 |
Strategies to improve in vivo toxicology outcomes for basic candidate drug molecules L Alcaraz, KK Chohan, N Blomberg, DS Brown, RJ Butlind, T Elebring, ... Bioorganic & medicinal chemistry letters, 2011 | 68 | 2011 |
Michael Additions to (R)-1-Acetyl-5-isopropoxy-3-pyrrolin-2-one and Subsequent N-Acyliminium Ion Generation: Synthesis of Enantiopure 1-Azabicycles and … T Luker, WJ Koot, H Hiemstra, WN Speckamp The Journal of Organic Chemistry 63 (2), 220-221, 1998 | 67 | 1998 |
Enantioselective formal total synthesis of roseophilin SJ Bamford, T Luker, WN Speckamp, H Hiemstra Organic Letters 2 (8), 1157-1160, 2000 | 59 | 2000 |
Permanganate oxidation of 1, 5, 9-trienes: Stereoselective synthesis of tetrahydrofuran-containing fragments RCD Brown, CJ Bataille, RM Hughes, A Kenney, TJ Luker The Journal of Organic Chemistry 67 (23), 8079-8085, 2002 | 54 | 2002 |
Molybdenum-mediated synthesis of quinazolin-4(3H)-ones via cyclocarbonylation using microwave irradiation B Roberts, D Liptrot, T Luker, MJ Stocks, C Barber, N Webb, R Dods, ... Tetrahedron letters 52 (29), 3793-3796, 2011 | 46 | 2011 |
Tandem reactions on a zirconocene template SF Fillery, GJ Gordon, T Luker, RJ Whitby Pure and applied chemistry 69 (3), 633-638, 1997 | 45 | 1997 |
Substituted indole-1-acetic acids as potent and selective CRTH2 antagonists—discovery of AZD1981 T Luker, R Bonnert, S Brough, AR Cook, MR Dickinson, I Dougall, ... Bioorganic & medicinal chemistry letters 21 (21), 6288-6292, 2011 | 42 | 2011 |
Elaboration of zirconacyclopentanes by sequential insertion of lithium chloroallylide and ketones or aldehydes T Luker, RJ Whitby Tetrahedron letters 35 (5), 785-788, 1994 | 42 | 1994 |
The regiochemistry of carbenoid insertion into zirconacycles GJ Gordon, T Luker, MW Tuckett, RJ Whitby Tetrahedron 56 (15), 2113-2129, 2000 | 40 | 2000 |
Organozirconium methods for the efficient construction of the bicyclo [9.3. 0] tetradecane dolabellane skeleton T Luker, RJ Whitby Tetrahedron letters 37 (42), 7661-7664, 1996 | 40 | 1996 |
Synthesis and reactivity of pyrrolidinone-and piperidinone-derived enol triflates T Luker, H Hiemstra, WN Speckamp Tetrahedron letters 37 (45), 8257-8260, 1996 | 39 | 1996 |
Insertion of phenyl azide and diphenyldiazomethane into bis (cyclopentadienyl) zirconacyclopentanes. Crystal structure of an 18-electron alkyl zirconocene triazenido complex T Luker, RJ Whitby, M Webster Journal of organometallic chemistry 492 (1), 53-57, 1995 | 33 | 1995 |
Deferitazole, a new orally active iron chelator RC Hider, X Kong, V Abbate, R Harland, K Conlon, T Luker Dalton Transactions 44 (11), 5197-5204, 2015 | 30 | 2015 |
Formation of medium-size bridged ring systems via ring-closing metathesis of 2, 5-disubstituted-2, 3-dihydro-1 H-pyrroles SJ Bamford, K Goubitz, HL van Lingen, T Luker, H Schenk, H Hiemstra Journal of the Chemical Society, Perkin Transactions 1, 345-351, 2000 | 25 | 2000 |
Prediction of efficacious inhalation lung doses via the use of in silico lung retention quantitative structure-activity relationship models and in vitro potency screens A Cooper, T Potter, T Luker Drug metabolism and disposition 38 (12), 2218-2225, 2010 | 24 | 2010 |
Trans-2-tritylcyclohexanol as a chiral auxiliary in permanganate-mediated oxidative cyclization of 2-methylenehept-5-enoates: Application to the synthesis of trans-(+)-linalool … AM Al Hazmi, NS Sheikh, CJR Bataille, AAM Al-Hadedi, SV Watkin, ... Organic letters 16 (19), 5104-5107, 2014 | 23 | 2014 |