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Tim Luker
Tim Luker
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Molybdenum-mediated carbonylation of aryl halides with nucleophiles using microwave irradiation
B Roberts, D Liptrot, L Alcaraz, T Luker, MJ Stocks
Organic Letters 12 (19), 4280-4283, 2010
1232010
Total synthesis of desoxoprosophylline: application of a lactam-derived enol triflate to natural product synthesis
T Luker, H Hiemstra, WN Speckamp
The Journal of Organic Chemistry 62 (11), 3592-3596, 1997
881997
Palladium catalysed amination of electron deficient halothiophenes
TJ Luker, HG Beaton, M Whiting, A Mete, DR Cheshire
Tetrahedron Letters 41 (40), 7731-7735, 2000
692000
Synthesis and further reactivity of functionalized lactam-derived enol triflates
T Luker, H Hiemstra, WN Speckamp
The Journal of Organic Chemistry 62 (23), 8131-8140, 1997
691997
Strategies to improve in vivo toxicology outcomes for basic candidate drug molecules
L Alcaraz, KK Chohan, N Blomberg, DS Brown, RJ Butlind, T Elebring, ...
Bioorganic & medicinal chemistry letters, 2011
682011
Michael Additions to (R)-1-Acetyl-5-isopropoxy-3-pyrrolin-2-one and Subsequent N-Acyliminium Ion Generation:  Synthesis of Enantiopure 1-Azabicycles and …
T Luker, WJ Koot, H Hiemstra, WN Speckamp
The Journal of Organic Chemistry 63 (2), 220-221, 1998
671998
Enantioselective formal total synthesis of roseophilin
SJ Bamford, T Luker, WN Speckamp, H Hiemstra
Organic Letters 2 (8), 1157-1160, 2000
592000
Permanganate oxidation of 1, 5, 9-trienes: Stereoselective synthesis of tetrahydrofuran-containing fragments
RCD Brown, CJ Bataille, RM Hughes, A Kenney, TJ Luker
The Journal of Organic Chemistry 67 (23), 8079-8085, 2002
542002
Molybdenum-mediated synthesis of quinazolin-4(3H)-ones via cyclocarbonylation using microwave irradiation
B Roberts, D Liptrot, T Luker, MJ Stocks, C Barber, N Webb, R Dods, ...
Tetrahedron letters 52 (29), 3793-3796, 2011
462011
Tandem reactions on a zirconocene template
SF Fillery, GJ Gordon, T Luker, RJ Whitby
Pure and applied chemistry 69 (3), 633-638, 1997
451997
Substituted indole-1-acetic acids as potent and selective CRTH2 antagonists—discovery of AZD1981
T Luker, R Bonnert, S Brough, AR Cook, MR Dickinson, I Dougall, ...
Bioorganic & medicinal chemistry letters 21 (21), 6288-6292, 2011
422011
Elaboration of zirconacyclopentanes by sequential insertion of lithium chloroallylide and ketones or aldehydes
T Luker, RJ Whitby
Tetrahedron letters 35 (5), 785-788, 1994
421994
The regiochemistry of carbenoid insertion into zirconacycles
GJ Gordon, T Luker, MW Tuckett, RJ Whitby
Tetrahedron 56 (15), 2113-2129, 2000
402000
Organozirconium methods for the efficient construction of the bicyclo [9.3. 0] tetradecane dolabellane skeleton
T Luker, RJ Whitby
Tetrahedron letters 37 (42), 7661-7664, 1996
401996
Synthesis and reactivity of pyrrolidinone-and piperidinone-derived enol triflates
T Luker, H Hiemstra, WN Speckamp
Tetrahedron letters 37 (45), 8257-8260, 1996
391996
Insertion of phenyl azide and diphenyldiazomethane into bis (cyclopentadienyl) zirconacyclopentanes. Crystal structure of an 18-electron alkyl zirconocene triazenido complex
T Luker, RJ Whitby, M Webster
Journal of organometallic chemistry 492 (1), 53-57, 1995
331995
Deferitazole, a new orally active iron chelator
RC Hider, X Kong, V Abbate, R Harland, K Conlon, T Luker
Dalton Transactions 44 (11), 5197-5204, 2015
302015
Formation of medium-size bridged ring systems via ring-closing metathesis of 2, 5-disubstituted-2, 3-dihydro-1 H-pyrroles
SJ Bamford, K Goubitz, HL van Lingen, T Luker, H Schenk, H Hiemstra
Journal of the Chemical Society, Perkin Transactions 1, 345-351, 2000
252000
Prediction of efficacious inhalation lung doses via the use of in silico lung retention quantitative structure-activity relationship models and in vitro potency screens
A Cooper, T Potter, T Luker
Drug metabolism and disposition 38 (12), 2218-2225, 2010
242010
Trans-2-tritylcyclohexanol as a chiral auxiliary in permanganate-mediated oxidative cyclization of 2-methylenehept-5-enoates: Application to the synthesis of trans-(+)-linalool …
AM Al Hazmi, NS Sheikh, CJR Bataille, AAM Al-Hadedi, SV Watkin, ...
Organic letters 16 (19), 5104-5107, 2014
232014
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