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Stefan Schildknecht
Stefan Schildknecht
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Geverifieerd e-mailadres voor uni-konstanz.de
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Rapid, complete and large‐scale generation of post‐mitotic neurons from the human LUHMES cell line
D Scholz, D Pöltl, A Genewsky, M Weng, T Waldmann, S Schildknecht, ...
Journal of neurochemistry 119 (5), 957-971, 2011
3652011
Adverse outcome pathways: opportunities, limitations and open questions
M Leist, A Ghallab, R Graepel, R Marchan, R Hassan, SH Bennekou, ...
Archives of Toxicology 91, 3477-3505, 2017
3242017
Role of reduced lipoic acid in the redox regulation of mitochondrial aldehyde dehydrogenase (ALDH-2) activity: implications for mitochondrial oxidative stress and nitrate tolerance
P Wenzel, U Hink, M Oelze, S Schuppan, K Schaeuble, S Schildknecht, ...
Journal of Biological Chemistry 282 (1), 792-799, 2007
1882007
Vascular aging: chronic oxidative stress and impairment of redox signaling—consequences for vascular homeostasis and disease
MM Bachschmid, S Schildknecht, R Matsui, R Zee, D Haeussler, ...
Annals of medicine 45 (1), 17-36, 2013
1772013
Oxidative and nitrative alpha‐synuclein modifications and proteostatic stress: implications for disease mechanisms and interventions in synucleinopathies
S Schildknecht, HR Gerding, C Karreman, M Drescher, HA Lashuel, ...
Journal of neurochemistry 125 (4), 491-511, 2013
1482013
Toxicity of organic and inorganic mercury species in differentiated human neurons and human astrocytes
H Lohren, L Blagojevic, R Fitkau, F Ebert, S Schildknecht, M Leist, ...
Journal of trace elements in medicine and biology 32, 200-208, 2015
1332015
Hydralazine is a powerful inhibitor of peroxynitrite formation as a possible explanation for its beneficial effects on prognosis in patients with congestive heart failure
A Daiber, M Oelze, M Coldewey, K Kaiser, C Huth, S Schildknecht, ...
Biochemical and biophysical research communications 338 (4), 1865-1874, 2005
1332005
Requirement of a dopaminergic neuronal phenotype for toxicity of low concentrations of 1-methyl-4-phenylpyridinium to human cells
S Schildknecht, D Pöltl, DM Nagel, F Matt, D Scholz, J Lotharius, ...
Toxicology and applied pharmacology 241 (1), 23-35, 2009
1282009
Neuroprotection by minocycline caused by direct and specific scavenging of peroxynitrite
S Schildknecht, R Pape, N Müller, M Robotta, A Marquardt, A Bürkle, ...
Journal of biological chemistry 286 (7), 4991-5002, 2011
1202011
In vitro research reproducibility: Keeping up high standards
C Hirsch, S Schildknecht
Frontiers in pharmacology 10, 492837, 2019
1172019
Redox regulation of vascular prostanoid synthesis by the nitric oxide-superoxide system
M Bachschmid, S Schildknecht, V Ullrich
Biochemical and biophysical research communications 338 (1), 536-542, 2005
1142005
Transcriptional and metabolic adaptation of human neurons to the mitochondrial toxicant MPP+
AK Krug, S Gutbier, L Zhao, D Pöltl, C Kullmann, V Ivanova, S Förster, ...
Cell death & disease 5 (5), e1222-e1222, 2014
1122014
A 3-dimensional human embryonic stem cell (hESC)-derived model to detect developmental neurotoxicity of nanoparticles
L Hoelting, B Scheinhardt, O Bondarenko, S Schildknecht, M Kapitza, ...
Archives of toxicology 87, 721-733, 2013
1112013
Alpha‐Synuclein binds to the inner membrane of mitochondria in an α‐helical conformation
M Robotta, HR Gerding, A Vogel, K Hauser, S Schildknecht, C Karreman, ...
Chembiochem 15 (17), 2499-2502, 2014
1092014
A transcriptome-based classifier to identify developmental toxicants by stem cell testing: design, validation and optimization for histone deacetylase inhibitors
E Rempel, L Hoelting, T Waldmann, NV Balmer, S Schildknecht, ...
Archives of toxicology 89, 1599-1618, 2015
992015
Redox regulation: a new challenge for pharmacology
D Frein, S Schildknecht, M Bachschmid, V Ullrich
Biochemical Pharmacology 70 (6), 811-823, 2005
962005
Generation of genetically-modified human differentiated cells for toxicological tests and the study of neurodegenerative diseases
S Schildknecht, C Karreman, D Pöltl, L Efrémova, C Kullmann, S Gutbier, ...
932013
An adverse outcome pathway for parkinsonian motor deficits associated with mitochondrial complex I inhibition
A Terron, A Bal-Price, A Paini, F Monnet-Tschudi, SH Bennekou, ...
Archives of Toxicology 92, 41-82, 2018
912018
Sensitivity of dopaminergic neuron differentiation from stem cells to chronic low-dose methylmercury exposure
B Zimmer, S Schildknecht, PB Kuegler, V Tanavde, S Kadereit, M Leist
Toxicological Sciences 121 (2), 357-367, 2011
872011
Tipping points and endogenous determinants of nigrostriatal degeneration by MPTP
S Schildknecht, DA Di Monte, R Pape, K Tieu, M Leist
Trends in Pharmacological Sciences 38 (6), 541-555, 2017
812017
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Artikelen 1–20