Insights into the catalytic mechanisms of phenylalanine and tryptophan hydroxylase from kinetic isotope effects on aromatic hydroxylation JA Pavon, PF Fitzpatrick Biochemistry 45 (36), 11030-11037, 2006 | 57 | 2006 |
Analysis of monoclonal antibody oxidation by simple mixed mode chromatography JA Pavon, X Li, S Chico, U Kishnani, S Soundararajan, J Cheung, H Li, ... Journal of Chromatography A 1431, 154-165, 2016 | 40 | 2016 |
Kinetic mechanism of phenylalanine hydroxylase: Intrinsic binding and rate constants from single-turnover experiments KM Roberts, JA Pavon, PF Fitzpatrick Biochemistry 52 (6), 1062-1073, 2013 | 34 | 2013 |
Intrinsic isotope effects on benzylic hydroxylation by the aromatic amino acid hydroxylases: evidence for hydrogen tunneling, coupled motion, and similar reactivities JA Pavon, PF Fitzpatrick Journal of the American Chemical Society 127 (47), 16414-16415, 2005 | 34 | 2005 |
Single turnover kinetics of tryptophan hydroxylase: Evidence for a new intermediate in the reaction of the aromatic amino acid hydroxylases JA Pavon, B Eser, MT Huynh, PF Fitzpatrick Biochemistry 49 (35), 7563-7571, 2010 | 26 | 2010 |
Identification and characterization of a residual host cell protein hexosaminidase B associated with N‐glycan degradation during the stability study of a therapeutic … X Li, Y An, J Liao, L Xiao, M Swanson, K Martinez‐Fonts, JA Pavon, ... Biotechnology progress 37 (3), e3128, 2021 | 25 | 2021 |
Selective tryptophan oxidation of monoclonal antibodies: Oxidative stress and modeling prediction JA Pavon, L Xiao, X Li, J Zhao, D Aldredge, E Dank, A Fridman, YH Liu Analytical chemistry 91 (3), 2192-2200, 2019 | 19 | 2019 |
Demonstration of a peroxide shunt in the tetrahydropterin-dependent aromatic amino acid monooxygenases JA Pavon, PF Fitzpatrick Journal of the American Chemical Society 131 (13), 4582-4583, 2009 | 16 | 2009 |
Determination of ultra-trace metal-protein interactions in co-formulated monoclonal antibody drug product by SEC-ICP-MS L Whitty-Léveillé, ZL VanAernum, JA Pavon, C Murphy, K Neal, W Forest, ... Mabs 15 (1), 2199466, 2023 | 1 | 2023 |
MECHANISM OF OXYGEN ACTIVATION AND HYDROXYLATION BY THE AROMATIC AMINO ACID HYDROXYLASES JA Pavon Texas A & M University, 2010 | | 2010 |