Optogenetic control of heart muscle in vitro and in vivo T Bruegmann, D Malan, M Hesse, T Beiert, CJ Fuegemann, ... Nature methods 7 (11), 897-900, 2010 | 510 | 2010 |
Optogenetic defibrillation terminates ventricular arrhythmia in mouse hearts and human simulations T Bruegmann, PM Boyle, CC Vogt, TV Karathanos, HJ Arevalo, ... The Journal of clinical investigation 126 (10), 3894-3904, 2016 | 179 | 2016 |
Systemic gene transfer enables optogenetic pacing of mouse hearts CC Vogt, T Bruegmann, D Malan, A Ottersbach, W Roell, BK Fleischmann, ... Cardiovascular research 106 (2), 338-343, 2015 | 114 | 2015 |
Optogenetic control of contractile function in skeletal muscle T Bruegmann, T Van Bremen, CC Vogt, T Send, BK Fleischmann, ... Nature communications 6 (1), 1-8, 2015 | 112 | 2015 |
Optogenetic termination of atrial fibrillation in mice T Bruegmann, T Beiert, CC Vogt, JW Schrickel, P Sasse Cardiovascular research 114 (5), 713-723, 2018 | 78 | 2018 |
Optogenetic activation of Gq signalling modulates pacemaker activity of cardiomyocytes T Beiert, T Bruegmann, P Sasse Cardiovascular research 102 (3), 507-516, 2014 | 73 | 2014 |
Frequency-dependent drug screening using optogenetic stimulation of human iPSC-derived cardiomyocytes H Lapp, T Bruegmann, D Malan, S Friedrichs, C Kilgus, A Heidsieck, ... Scientific reports 7 (1), 1-12, 2017 | 60 | 2017 |
Improved heart repair upon myocardial infarction: Combination of magnetic nanoparticles and tailored magnets strongly increases engraftment of myocytes A Ottersbach, O Mykhaylyk, A Heidsieck, D Eberbeck, S Rieck, ... Biomaterials 155, 176-190, 2018 | 54 | 2018 |
Optical control of L-type Ca 2+ channels using a diltiazem photoswitch T Fehrentz, FME Huber, N Hartrampf, T Bruegmann, JA Frank, NHF Fine, ... Nature chemical biology 14 (8), 764-767, 2018 | 53 | 2018 |
Optogenetic stimulation of G s-signaling in the heart with high spatio-temporal precision P Makowka, T Bruegmann, V Dusend, D Malan, T Beiert, M Hesse, ... Nature communications 10 (1), 1-9, 2019 | 42 | 2019 |
Optogenetic termination of cardiac arrhythmia: mechanistic enlightenment and therapeutic application? P Sasse, M Funken, T Beiert, T Bruegmann Frontiers in physiology 10, 675, 2019 | 41 | 2019 |
Optogenetic hyperpolarization of cardiomyocytes terminates ventricular arrhythmia M Funken, D Malan, P Sasse, T Bruegmann Frontiers in physiology 10, 498, 2019 | 37 | 2019 |
Synchronization of excitable cardiac cultures of different origin NN Agladze, OV Halaidych, VA Tsvelaya, T Bruegmann, C Kilgus, ... Biomaterials science 5 (9), 1777-1785, 2017 | 35 | 2017 |
Frequency-dependent multi-well cardiotoxicity screening enabled by optogenetic stimulation S Rehnelt, D Malan, K Juhasz, B Wolters, L Doerr, M Beckler, ... International journal of molecular sciences 18 (12), 2634, 2017 | 29 | 2017 |
Selective optogenetic control of Gq signaling using human Neuropsin A Wagdi, D Malan, U Sathyanarayanan, JS Beauchamp, M Vogt, D Zipf, ... Nature communications 13 (1), 1-18, 2022 | 28 | 2022 |
Carnosine synthase deficiency is compatible with normal skeletal muscle and olfactory function but causes reduced olfactory sensitivity in aging mice L Wang-Eckhardt, A Bastian, T Bruegmann, P Sasse, M Eckhardt Journal of Biological Chemistry 295 (50), 17100-17113, 2020 | 22 | 2020 |
No light without the dark: Perspectives and hindrances for translation of cardiac optogenetics C Richter, T Bruegmann Progress in biophysics and molecular biology 154, 39-50, 2020 | 21 | 2020 |
Direct optogenetic stimulation of smooth muscle cells to control gastric contractility M Vogt, B Schulz, A Wagdi, J Lebert, GJ van Belle, J Christoph, ... Theranostics 11 (11), 5569, 2021 | 17 | 2021 |
Combined fibre atrophy and decreased muscle regeneration capacity driven by mitochondrial DNA alterations underlie the development of sarcopenia S Kimoloi, A Sen, S Guenther, T Braun, T Brügmann, P Sasse, ... Journal of Cachexia, Sarcopenia and Muscle, 2022 | 15 | 2022 |
Towards the clinical translation of optogenetic skeletal muscle stimulation LA Gundelach, MA Hüser, D Beutner, P Ruther, T Bruegmann Pflügers Archiv-European Journal of Physiology 472, 527-545, 2020 | 14 | 2020 |