Mark S. Hipp
Mark S. Hipp
Groupleader, University Medical Center Groningen
Geverifieerd e-mailadres voor umcg.nl - Homepage
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Molecular chaperone functions in protein folding and proteostasis
YE Kim, MS Hipp, A Bracher, M Hayer-Hartl, F Ulrich Hartl
Annual review of biochemistry 82, 323-355, 2013
11752013
Proteostasis impairment in protein-misfolding and-aggregation diseases
MS Hipp, SH Park, FU Hartl
Trends in cell biology 24 (9), 506-514, 2014
5042014
PolyQ proteins interfere with nuclear degradation of cytosolic proteins by sequestering the Sis1p chaperone
SH Park, Y Kukushkin, R Gupta, T Chen, A Konagai, MS Hipp, ...
Cell 154 (1), 134-145, 2013
3102013
Cytoplasmic protein aggregates interfere with nucleocytoplasmic transport of protein and RNA
AC Woerner, F Frottin, D Hornburg, LR Feng, F Meissner, M Patra, ...
Science 351 (6269), 173-176, 2016
2882016
The proteostasis network and its decline in ageing
MS Hipp, P Kasturi, FU Hartl
Nature reviews Molecular cell biology 20 (7), 421-435, 2019
2742019
FAT10, a ubiquitin-independent signal for proteasomal degradation
MS Hipp, B Kalveram, S Raasi, M Groettrup, G Schmidtke
Molecular and cellular biology 25 (9), 3483-3491, 2005
1982005
In situ structure of neuronal C9orf72 poly-GA aggregates reveals proteasome recruitment
Q Guo, C Lehmer, A Martínez-Sánchez, T Rudack, F Beck, H Hartmann, ...
Cell 172 (4), 696-705. e12, 2018
1752018
Ubiquitin accumulation in autophagy-deficient mice is dependent on the Nrf2-mediated stress response pathway: a potential role for protein aggregation in autophagic substrate …
BE Riley, SE Kaiser, TA Shaler, ACY Ng, T Hara, MS Hipp, K Lage, ...
Journal of Cell Biology 191 (3), 537-552, 2010
1582010
In situ architecture and cellular interactions of PolyQ inclusions
FJB Bäuerlein, I Saha, A Mishra, M Kalemanov, A Martínez-Sánchez, ...
Cell 171 (1), 179-187. e10, 2017
1562017
Indirect inhibition of 26S proteasome activity in a cellular model of Huntington’s disease
MS Hipp, CN Patel, K Bersuker, BE Riley, SE Kaiser, TA Shaler, ...
Journal of Cell Biology 196 (5), 573-587, 2012
1532012
The nucleolus functions as a phase-separated protein quality control compartment
F Frottin, F Schueder, S Tiwary, R Gupta, R Körner, T Schlichthaerle, ...
Science 365 (6451), 342-347, 2019
1222019
NEDD8 ultimate buster-1L interacts with the ubiquitin-like protein FAT10 and accelerates its degradation
MS Hipp, S Raasi, M Groettrup, G Schmidtke
Journal of Biological Chemistry 279 (16), 16503-16510, 2004
972004
Proteasome inhibition leads to NF‐κB‐independent IL‐8 transactivation in human endothelial cells through induction of AP‐1
MS Hipp, C Urbich, P Mayer, J Wischhusen, M Weller, M Kracht, ...
European journal of immunology 32 (8), 2208-2217, 2002
792002
The UBA domains of NUB1L are required for binding but not for accelerated degradation of the ubiquitin-like modifier FAT10
G Schmidtke, B Kalveram, E Weber, P Bochtler, S Lukasiak, MS Hipp, ...
Journal of Biological Chemistry 281 (29), 20045-20054, 2006
692006
Proteotoxic stress and ageing triggers the loss of redox homeostasis across cellular compartments
J Kirstein, D Morito, T Kakihana, M Sugihara, A Minnen, MS Hipp, ...
The EMBO journal 34 (18), 2334-2349, 2015
652015
Spatiotemporal proteomic profiling of Huntington’s disease inclusions reveals widespread loss of protein function
F Hosp, S Gutiérrez-Ángel, MH Schaefer, J Cox, F Meissner, MS Hipp, ...
Cell reports 21 (8), 2291-2303, 2017
572017
Heat shock response activation exacerbates inclusion body formation in a cellular model of Huntington disease
K Bersuker, MS Hipp, B Calamini, RI Morimoto, RR Kopito
Journal of Biological Chemistry 288 (33), 23633-23638, 2013
512013
Overexpression of Q-rich prion-like proteins suppresses polyQ cytotoxicity and alters the polyQ interactome
L Ripaud, V Chumakova, M Antonin, AR Hastie, S Pinkert, R Körner, ...
Proceedings of the National Academy of Sciences 111 (51), 18219-18224, 2014
432014
Functional modules of the proteostasis network
GG Jayaraj, MS Hipp, FU Hartl
Cold Spring Harbor perspectives in biology 12 (1), a033951, 2020
392020
The formation, function and regulation of amyloids: insights from structural biology
M Landreh, MR Sawaya, MS Hipp, DS Eisenberg, K Wüthrich, FU Hartl
Journal of internal medicine 280 (2), 164-176, 2016
392016
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Artikelen 1–20