| Small-molecule proteostasis regulators for protein conformational diseases B Calamini, MC Silva, F Madoux, DM Hutt, S Khanna, MA Chalfant, ... Nature chemical biology 8 (2), 185-196, 2012 | 249 | 2012 |
| Targeted degradation of aberrant tau in frontotemporal dementia patient-derived neuronal cell models MC Silva, FM Ferguson, Q Cai, KA Donovan, G Nandi, D Patnaik, T Zhang, ... elife 8, e45457, 2019 | 215 | 2019 |
| A thermoanalytic and kinetic study of sunflower oil A Souza, JC Santos, MM Conceição, MC Silva, S Prasad Brazilian Journal of Chemical Engineering 21, 265-273, 2004 | 193 | 2004 |
| Inhibition of p25/Cdk5 attenuates tauopathy in mouse and iPSC models of frontotemporal dementia J Seo, O Kritskiy, LA Watson, SJ Barker, D Dey, WK Raja, YT Lin, T Ko, ... Journal of Neuroscience 37 (41), 9917-9924, 2017 | 142 | 2017 |
| A genetic screening strategy identifies novel regulators of the proteostasis network MC Silva, S Fox, M Beam, H Thakkar, MD Amaral, RI Morimoto PLoS genetics 7 (12), e1002438, 2011 | 134 | 2011 |
| Neuronal signaling modulates protein homeostasis in Caenorhabditis elegans post-synaptic muscle cells SM Garcia, MO Casanueva, MC Silva, MD Amaral, RI Morimoto Genes & development 21 (22), 3006-3016, 2007 | 130 | 2007 |
| Prolonged tau clearance and stress vulnerability rescue by pharmacological activation of autophagy in tauopathy neurons MC Silva, GA Nandi, S Tentarelli, IK Gurrell, T Jamier, D Lucente, ... Nature Communications 11 (1), 3258, 2020 | 111 | 2020 |
| An inhibitor of the proteasomal deubiquitinating enzyme USP14 induces tau elimination in cultured neurons M Boselli, BH Lee, J Robert, MA Prado, SW Min, C Cheng, MC Silva, ... Journal of Biological Chemistry 292 (47), 19209-19225, 2017 | 111 | 2017 |
| Human iPSC-derived neuronal model of tau-A152T frontotemporal dementia reveals tau-mediated mechanisms of neuronal vulnerability MC Silva, C Cheng, W Mair, S Almeida, H Fong, MHU Biswas, Z Zhang, ... Stem cell reports 7 (3), 325-340, 2016 | 110 | 2016 |
| ELAVL4, splicing, and glutamatergic dysfunction precede neuron loss in MAPT mutation cerebral organoids KR Bowles, MC Silva, K Whitney, T Bertucci, JE Berlind, JD Lai, JC Garza, ... Cell 184 (17), 4547-4563. e17, 2021 | 87 | 2021 |
| Tauopathies: Deciphering disease mechanisms to develop effective therapies MC Silva, SJ Haggarty International journal of molecular sciences 21 (23), 8948, 2020 | 78 | 2020 |
| A comprehensive resource for induced pluripotent stem cells from patients with primary tauopathies CM Karch, AW Kao, A Karydas, K Onanuga, R Martinez, A Argouarch, ... Stem cell reports 13 (5), 939-955, 2019 | 71 | 2019 |
| Parâmetros clínicos, hematológicos, bioquímicos e hormonais de bovinos submetidos ao estresse calórico F Ferreira, WE Campos, AU Carvalho, MFA Pires, ML Martinez, M Silva, ... Arquivo Brasileiro de Medicina Veterinária e Zootecnia 61, 769-776, 2009 | 70 | 2009 |
| Advancing drug discovery for neuropsychiatric disorders using patient-specific stem cell models SJ Haggarty, MC Silva, A Cross, NJ Brandon, RH Perlis Molecular and Cellular Neuroscience 73, 104-115, 2016 | 68 | 2016 |
| Human pluripotent stem cell–derived models and drug screening in CNS precision medicine MC Silva, SJ Haggarty Annals of the New York Academy of Sciences 1471 (1), 18-56, 2020 | 62 | 2020 |
| Neuronal reprograming of protein homeostasis by calcium-dependent regulation of the heat shock response MC Silva, MD Amaral, RI Morimoto PLoS genetics 9 (8), e1003711, 2013 | 36 | 2013 |
| Dynamic imaging by fluorescence correlation spectroscopy identifies diverse populations of polyglutamine oligomers formed in vivo M Beam, MC Silva, RI Morimoto Journal of Biological Chemistry 287 (31), 26136-26145, 2012 | 33 | 2012 |
| Occurrence of paralytic shellfish toxins- PST in southern Brazilian waters LA Proença, N Lagos, L Rörig, M Silva, S Guimarães Ciencia e Cultura(Sao Paulo) 51 (1), 16-21, 1999 | 24 | 1999 |
| Salud México D Sandra, E Argueta, NH Wacher, M Silva, L Valdez, M Cruz, ... S. de, Virtual, D., Social, IM del S., Mediavilla, J., Fernández, M., Nocito …, 2016 | 23 | 2016 |
| Targeting tau mitigates mitochondrial fragmentation and oxidative stress in amyotrophic lateral sclerosis T Petrozziello, EA Bordt, AN Mills, SE Kim, E Sapp, BA Devlin, ... Molecular neurobiology 59 (1), 683-702, 2022 | 22 | 2022 |
Bradford DickersonProfessor of Neurology, Harvard Medical School & Massachusetts General HospitalVerified email at mgh.harvard.edu
