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Sara Nolbrant
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Predictive markers guide differentiation to improve graft outcome in clinical translation of hESC-based therapy for Parkinson’s disease
A Kirkeby, S Nolbrant, K Tiklova, A Heuer, N Kee, T Cardoso, ...
Cell stem cell 20 (1), 135-148, 2017
2752017
Generation of high-purity human ventral midbrain dopaminergic progenitors for in vitro maturation and intracerebral transplantation
S Nolbrant, A Heuer, M Parmar, A Kirkeby
Nature protocols 12 (9), 1962-1979, 2017
2162017
Single-cell RNA sequencing reveals midbrain dopamine neuron diversity emerging during mouse brain development
K Tiklová, ÅK Björklund, L Lahti, A Fiorenzano, S Nolbrant, L Gillberg, ...
Nature communications 10 (1), 581, 2019
2122019
Single-cell analysis reveals a close relationship between differentiating dopamine and subthalamic nucleus neuronal lineages
N Kee, N Volakakis, A Kirkeby, L Dahl, H Storvall, S Nolbrant, L Lahti, ...
Cell stem cell 20 (1), 29-40, 2017
1432017
A systematic capsid evolution approach performed in vivo for the design of AAV vectors with tailored properties and tropism
M Davidsson, G Wang, P Aldrin-Kirk, T Cardoso, S Nolbrant, M Hartnor, ...
Proceedings of the National Academy of Sciences 116 (52), 27053-27062, 2019
1362019
Single cell transcriptomics identifies stem cell-derived graft composition in a model of Parkinson’s disease
K Tiklová, S Nolbrant, A Fiorenzano, ÅK Björklund, Y Sharma, A Heuer, ...
Nature communications 11 (1), 2434, 2020
802020
hESC-derived dopaminergic transplants integrate into basal ganglia circuitry in a preclinical model of Parkinson’s disease
AF Adler, T Cardoso, S Nolbrant, B Mattsson, DB Hoban, U Jarl, ...
Cell reports 28 (13), 3462-3473. e5, 2019
742019
Target‐specific forebrain projections and appropriate synaptic inputs of hESC‐derived dopamine neurons grafted to the midbrain of Parkinsonian rats
T Cardoso, AF Adler, B Mattsson, DB Hoban, S Nolbrant, JN Wahlestedt, ...
Journal of Comparative Neurology 526 (13), 2133-2146, 2018
542018
Direct reprogramming of human fetal-and stem cell-derived glial progenitor cells into midbrain dopaminergic neurons
S Nolbrant, J Giacomoni, DB Hoban, A Bruzelius, M Birtele, ...
Stem Cell Reports 15 (4), 869-882, 2020
242020
Profiling of lincRNAs in human pluripotent stem cell derived forebrain neural progenitor cells
DA Grassi, PL Brattås, ME Jönsson, D Atacho, O Karlsson, S Nolbrant, ...
Heliyon 6 (1), 2020
132020
Robust derivation of transplantable dopamine neurons from human pluripotent stem cells by timed retinoic acid delivery
Z Alekseenko, JM Dias, AF Adler, M Kozhevnikova, JA van Lunteren, ...
Nature Communications 13 (1), 3046, 2022
112022
The putative tumor suppressor gene EphA7 is a novel BMI-1 target
G Prost, S Braun, F Hertwig, M Winkler, L Jagemann, S Nolbrant, IV Leefa, ...
Oncotarget 7 (36), 58203, 2016
102016
Single cell gene expression analysis reveals human stem cell-derived graft composition in a cell therapy model of Parkinson’s disease
K Tiklová, S Nolbrant, A Fiorenzano, ÅK Björklund, Y Sharma, A Heuer, ...
bioRxiv, 720870, 2019
72019
Barcoded Rational AAV Vector Evolution enables systematic in vivo mapping of peptide binding motifs
M Davidsson, G Wang, P Aldrin-Kirk, T Cardoso, S Nolbrant, M Hartnor, ...
bioRxiv, 335372, 2018
72018
A novel two-factor monosynaptic TRIO tracing method for assessment of circuit integration of hESC-derived dopamine transplants
P Aldrin-Kirk, M Åkerblom, T Cardoso, S Nolbrant, AF Adler, X Liu, ...
Stem Cell Reports 17 (1), 159-172, 2022
42022
Human embryonic stem cell-derived dopaminergic grafts alleviate L-DOPA induced dyskinesia
OF Elabi, R Pass, I Sormonta, S Nolbrant, N Drummond, A Kirkeby, ...
Journal of Parkinson's disease 12 (6), 1881-1896, 2022
32022
Post-transcriptional mechanisms distinguish human and chimp forebrain progenitor cells
DA Grassi, PL Brattås, JG Valdés, M Rezeli, ME Jönsson, S Nolbrant, ...
bioRxiv, 582197, 2019
32019
Deconvolution of spatial sequencing provides accurate characterization of hESC-derived DA transplants in vivo
J Rájová, M Davidsson, M Avallone, M Hartnor, P Aldrin-Kirk, T Cardoso, ...
Molecular Therapy-Methods & Clinical Development 29, 381-394, 2023
12023
Neural tube patterning: From a minimal model for rostrocaudal patterning toward an integrated 3D model
M Brambach, A Ernst, S Nolbrant, J Drouin-Ouellet, A Kirkeby, M Parmar, ...
Iscience 24 (6), 2021
12021
Unbiased Gene Expression Analysis Reveals Human Stem Cell-Derived Graft Composition in a Cell Therapy Model of Parkinson's Disease
S Nolbrant, K Tiklova, A Fiorenzano, AK Bjorklund, Y Sharma, A Heuer, ...
CELL TRANSPLANTATION 30, 16-16, 2021
2021
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