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Wei Wang
Wei Wang
Syneos Health
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Reduced H3K27me3 and DNA hypomethylation are major drivers of gene expression in K27M mutant pediatric high-grade gliomas
S Bender, Y Tang, AM Lindroth, V Hovestadt, DTW Jones, M Kool, ...
Cancer cell 24 (5), 660-672, 2013
7412013
Enhancer hijacking activates GFI1 family oncogenes in medulloblastoma
PA Northcott, C Lee, T Zichner, AM Stütz, S Erkek, D Kawauchi, DJH Shih, ...
Nature 511 (7510), 428-434, 2014
6652014
BCAT1 promotes cell proliferation through amino acid catabolism in gliomas carrying wild-type IDH1
M Tönjes, S Barbus, YJ Park, W Wang, M Schlotter, AM Lindroth, ...
Nature medicine 19 (7), 901-908, 2013
4652013
Decoding the regulatory landscape of medulloblastoma using DNA methylation sequencing
V Hovestadt, DTW Jones, S Picelli, W Wang, M Kool, PA Northcott, ...
Nature 510 (7506), 537-541, 2014
4382014
BCAT1 restricts αKG levels in AML stem cells leading to IDHmut-like DNA hypermethylation
S Raffel, M Falcone, N Kneisel, J Hansson, W Wang, C Lutz, L Bullinger, ...
Nature 551 (7680), 384-388, 2017
3192017
Genome-wide high-throughput integrome analyses by nrLAM-PCR and next-generation sequencing
A Paruzynski, A Arens, R Gabriel, CC Bartholomae, S Scholz, W Wang, ...
Nature protocols 5 (8), 1379-1395, 2010
2242010
Comprehensive genomic access to vector integration in clinical gene therapy
R Gabriel, R Eckenberg, A Paruzynski, CC Bartholomae, A Nowrouzi, ...
Nature medicine 15 (12), 1431-1436, 2009
2172009
Tagmentation-based whole-genome bisulfite sequencing
Q Wang, L Gu, A Adey, B Radlwimmer, W Wang, V Hovestadt, M Bähr, ...
Nature protocols 8 (10), 2022-2032, 2013
1792013
Hepatocyte‐targeted expression by integrase‐defective lentiviral vectors induces antigen‐specific tolerance in mice with low genotoxic risk
J Mátrai, A Cantore, CC Bartholomae, A Annoni, W Wang, ...
Hepatology 53 (5), 1696-1707, 2011
1542011
DNA methylome analysis in Burkitt and follicular lymphomas identifies differentially methylated regions linked to somatic mutation and transcriptional control
H Kretzmer, SH Bernhart, W Wang, A Haake, MA Weniger, AK Bergmann, ...
Nature genetics 47 (11), 1316-1325, 2015
1432015
Successful engraftment of gene-corrected hematopoietic stem cells in non-conditioned patients with Fanconi anemia
P Rio, S Navarro, W Wang, R Sanchez-Dominguez, RM Pujol, ...
Nature medicine 25 (9), 1396-1401, 2019
1392019
Extensive methylation of promoter sequences silences lentiviral transgene expression during stem cell differentiation in vivo
F Herbst, CR Ball, F Tuorto, A Nowrouzi, W Wang, O Zavidij, SM Dieter, ...
Molecular Therapy 20 (5), 1014-1021, 2012
1382012
Spatially clustered loci with multiple enhancers are frequent targets of HIV-1 integration
B Lucic, HC Chen, M Kuzman, E Zorita, J Wegner, V Minneker, W Wang, ...
Nature communications 10 (1), 4059, 2019
972019
Glioblastoma epigenome profiling identifies SOX10 as a master regulator of molecular tumour subtype
Y Wu, M Fletcher, Z Gu, Q Wang, B Costa, A Bertoni, KH Man, M Schlotter, ...
Nature communications 11 (1), 6434, 2020
552020
Generation and clinical application of gene-modified autologous epidermal sheets in Netherton syndrome: lessons learned from a phase 1 trial
WL Di, SM Lwin, A Petrova, C Bernadis, F Syed, F Farzaneh, D Moulding, ...
Human gene therapy 30 (9), 1067-1078, 2019
352019
Mesenchymal stem cells to treat Crohn's disease with fistula
X Zhang, Y Zhang, W Wang, YQ Wei, H Deng
Human Gene Therapy 28 (7), 534-540, 2017
282017
In utero gene therapy (IUGT) using GLOBE lentiviral vector phenotypically corrects the heterozygous humanised mouse model and its progress can be monitored using MRI techniques
P Shangaris, SP Loukogeorgakis, S Subramaniam, C Flouri, LH Jackson, ...
Scientific Reports 9 (1), 11592, 2019
212019
Microstructure evolution of sandwich graphite oxide/interlayer-embedded Au nanoparticles induced from γ-rays for carcinoembryonic antigen biosensor
X Zhao, W Wang, L Liu, Y Hu, Z Xu, L Liu, N Wu, N Li
Nanotechnology 30 (49), 495501, 2019
182019
L, Roncarolo MG, Schmidt M, Vandendriessche T, Naldini L: Hepatocyte-targeted expression by integrase-defective lentiviral vectors induces antigen-specific tolerance in mice …
J Mátrai, A Cantore, CC Bartholomae, A Annoni, W Wang, ...
Hepatology 53 (5), 1696-1707, 2011
122011
The LAM-PCR method to sequence LV integration sites
W Wang, CC Bartholomae, R Gabriel, A Deichmann, M Schmidt
Lentiviral Vectors and Exosomes as Gene and Protein Delivery Tools, 107-120, 2016
72016
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Artikelen 1–20