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Robert Bentham
Robert Bentham
Geverifieerd e-mailadres voor ucl.ac.uk
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Meta-analysis of tumor-and T cell-intrinsic mechanisms of sensitization to checkpoint inhibition
K Litchfield, JL Reading, C Puttick, K Thakkar, C Abbosh, R Bentham, ...
Cell 184 (3), 596-614. e14, 2021
5552021
The mitochondrial calcium uniporter regulates breast cancer progression via HIF‐1α
A Tosatto, R Sommaggio, C Kummerow, RB Bentham, TS Blacker, ...
EMBO molecular medicine 8 (5), 569-585, 2016
2252016
Mitochondria form contact sites with the nucleus to couple prosurvival retrograde response
R Desai, DA East, L Hardy, D Faccenda, M Rigon, J Crosby, MS Alvarez, ...
Science advances 6 (51), eabc9955, 2020
962020
The evolution of lung cancer and impact of subclonal selection in TRACERx
AM Frankell, M Dietzen, M Al Bakir, EL Lim, T Karasaki, S Ward, ...
Nature 616 (7957), 525-533, 2023
792023
Using DNA sequencing data to quantify T cell fraction and therapy response
R Bentham, K Litchfield, TBK Watkins, EL Lim, R Rosenthal, ...
Nature 597 (7877), 555-560, 2021
402021
Inositol trisphosphate receptor-mediated Ca2+ signalling stimulates mitochondrial function and gene expression in core myopathy patients
M Suman, JA Sharpe, RB Bentham, VN Kotiadis, M Menegollo, ...
Human Molecular Genetics 27 (13), 2367-2382, 2018
192018
MCbiclust: a novel algorithm to discover large-scale functionally related gene sets from massive transcriptomics data collections
RB Bentham, K Bryson, G Szabadkai
Nucleic acids research 45 (15), 8712-8730, 2017
162017
No evidence for a local renin-angiotensin system in liver mitochondria
R Astin, R Bentham, S Djafarzadeh, JA Horscroft, RE Kuc, PS Leung, ...
Scientific reports 3 (1), 2467, 2013
162013
Macrophages induce malignant traits in mammary epithelium via IKKε/TBK1 kinases and the serine biosynthesis pathway
E Wilcz‐Villega, E Carter, A Ironside, R Xu, I Mataloni, J Holdsworth, ...
EMBO molecular medicine 12 (2), e10491, 2020
132020
The breast cancer oncogene IKKε coordinates mitochondrial function and serine metabolism
R Xu, W Jones, E Wilcz‐Villega, ASH Costa, V Rajeeve, RB Bentham, ...
EMBO reports 21 (9), e48260, 2020
62020
Mitochondria form cholesterol tethered contact sites with the Nucleus to regulate retrograde response
R Desai, DA East, L Hardy, J Crosby, M Rigon, D Faccenda, MS Alvarez, ...
BioRxiv, 445411, 2019
32019
Biclustering analysis of co-regulation patterns in nuclear-encoded mitochondrial genes and metabolic pathways
RB Bentham, K Bryson, G Szabadkai
Cancer Metabolism: Methods and Protocols, 469-478, 2019
22019
The evolution of lung cancer and impact of subclonal selection in TRACERx
C Swanton, N McGranahan, M Jamal-Hanjani, AM Frankell, M Dietzen, ...
Nature 616 (7957), 2023
12023
Mitochondria Form Contact Sites with the Nucleus to Couple Pro-Survival Retrograde Response
R Desai, DA East, L Hardy, J Crosby, M Rigon, D Faccenda, MS Alvarez, ...
12019
The origins and clinical impact of extrachromosomal DNA across 39 cancers
C Bailey, O Pich, K Thol, J Luebeck, G Stavrou, TB Watkins, NE Weiser, ...
Cancer Research 84 (6_Supplement), 3887-3887, 2024
2024
Pervasive HLA disruption fuels cancer evolution
C Puttick, TP Jones, M Leung, O Pich, FG Cancino, J Liu, M Varas-Godoy, ...
Cancer Research 84 (6_Supplement), 1201-1201, 2024
2024
Multi-state gene cluster switches determining the adaptive mitochondrial and metabolic landscape of breast cancer
M Menegollo, R Bentham, N Patani, RC Stein, M Yuneva, G Szabadkai
Cancer Research 84 (6_Supplement), 7559-7559, 2024
2024
Whole genome sequencing reveals differences in the genetic landscape of interval and screen-detected breast cancer
R Houlston, C Mills, A Sud, A Everall, D Chubb, S Lawrence, B Kinnersley, ...
2024
Whole genome sequencing refines stratification and therapy of patients with clear cell renal cell carcinoma
R Houlston, R Culliford, S Lawrence, C Mills, Z Tippu, D Chubb, ...
Research Square, rs. 3. rs-3675752, 2023
2023
Whole-genome sequencing uncovers the genomic determinants of therapeutic resistance to immune checkpoint blockade
K Litchfield, B Simpson, H Cha, A Castro, R Bentham, L Ryan, M Dietzen, ...
2023
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Artikelen 1–20