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Shakil Saghir
Shakil Saghir
President, ToxInternational, Inc.
Verified email at aku.edu - Homepage
Title
Cited by
Cited by
Year
Method and system for monitoring and analyzing compliance with internal dosing regimen
C Jones, P Mercure, S Saghir
US Patent App. 11/693,404, 2007
1832007
Strategies to assess systemic exposure of chemicals in subchronic/chronic diet and drinking water studies
SA Saghir, AL Mendrala, MJ Bartels, SJ Day, SC Hansen, JM Sushynski, ...
Toxicology and applied pharmacology 211 (3), 245-260, 2006
642006
Ontogeny of mammalian metabolizing enzymes in humans and animals used in toxicological studies
SA Saghir, SA Khan, AT McCoy
Critical reviews in toxicology 42 (5), 323-357, 2012
592012
Low-dose pharmacokinetics and oral bioavailability of dichloroacetate in naive and GST-zeta-depleted rats.
SA Saghir, IR Schultz
Environmental Health Perspectives 110 (8), 757-763, 2002
562002
Assessment of diurnal systemic dose of agrochemicals in regulatory toxicity testing–an integrated approach without additional animal use
SA Saghir, MJ Bartels, DL Rick, AT McCoy, RJ Rasoulpour, ...
Regulatory Toxicology and Pharmacology 63 (2), 321-332, 2012
472012
Differential and Non-Uniform Tissue and Brain Distribution of Two Distinct 14C-Hexachlorobiphenyls in Weanling Rats
SA Saghir, LG Hansen, KR Holmes, PRS Kodavanti
Toxicological Sciences 54 (1), 60-70, 2000
452000
Use of toxicokinetics to support chemical evaluation: Informing high dose selection and study interpretation
S Creton, SA Saghir, MJ Bartels, R Billington, JS Bus, W Davies, MP Dent, ...
Regulatory Toxicology and Pharmacology 62 (2), 241-247, 2012
432012
Mechanism of trifluralin-induced thyroid tumors in rats
SA Saghir, GD Charles, MJ Bartels, LHL Kan, MD Dryzga, KA Brzak, ...
Toxicology letters 180 (1), 38-45, 2008
412008
An F1-Extended One-Generation Reproductive Toxicity Study in Crl:CD(SD) Rats With 2,4-Dichlorophenoxyacetic Acid
MS Marty, BH Neal, CL Zablotny, BL Yano, AK Andrus, MR Woolhiser, ...
toxicological sciences 136 (2), 527-547, 2013
392013
Preparation, characterization, and scale-up of ketoconazole with enhanced dissolution and bioavailability
EJ Elder, JC Evans, BD Scherzer, JE Hitt, GB Kupperblatt, SA Saghir, ...
Drug development and industrial pharmacy 33 (7), 755-765, 2007
392007
Effects of black carbon and montmorillonite clay on multiphasic hexachlorobenzene desorption from sediments
Y Chai, X Qiu, JW Davis, RA Budinsky Jr, MJ Bartels, SA Saghir
Chemosphere 69 (8), 1204-1212, 2007
332007
Comparison of vitamin D replacement strategies with high-dose intramuscular or oral cholecalciferol: a prospective intervention study
MQ Masood, A Khan, S Awan, F Dar, S Naz, G Naureen, S Saghir, ...
Endocrine Practice 21 (10), 1125-1133, 2015
322015
Life-stage-, sex-, and dose-dependent dietary toxicokinetics and relationship to toxicity of 2, 4-dichlorophenoxyacetic acid (2, 4-D) in rats: implications for toxicity test …
SA Saghir, MS Marty, CL Zablotny, JK Passage, AW Perala, BH Neal, ...
toxicological sciences 136 (2), 294-307, 2013
322013
Kinetics of monochloroacetic acid in adult male rats after intravenous injection of a subtoxic and a toxic dose
SA Saghir, K Fried, KK Rozman
Journal of Pharmacology and Experimental Therapeutics 296 (2), 612-622, 2001
282001
Physiologically based pharmacokinetic model development and simulations for ethylene dichloride (1, 2-dichloroethane) in rats
LM Sweeney, SA Saghir, ML Gargas
Regulatory Toxicology and Pharmacology 51 (3), 311-323, 2008
272008
Mechanism of ethylbenzene-induced mouse-specific lung tumor: metabolism of ethylbenzene by rat, mouse, and human liver and lung microsomes
SA Saghir, DL Rick, EL McClymont, F Zhang, MJ Bartels, JS Bus
Toxicological sciences 107 (2), 352-366, 2009
262009
Short-term distribution, metabolism, and excretion of 2, 2′, 5-tri-, 2, 2′, 4, 4′-tetra-, and 3, 3′, 4, 4′-tetrachlorobiphenyls in prepubertal rats
SA Saghir, GD Koritz, LG Hansen
Archives of environmental contamination and toxicology 36, 213-220, 1999
241999
Effects of aging and sediment composition on hexachlorobenzene desorption resistance compared to oral bioavailability in rats
Y Chai, JW Davis, SA Saghir, X Qiu, RA Budinsky Jr, MJ Bartels
Chemosphere 72 (3), 432-441, 2008
232008
In vitro metabolism and covalent binding of ethylbenzene to microsomal protein as a possible mechanism of ethylbenzene-induced mouse lung tumorigenesis
SA Saghir, F Zhang, DL Rick, L Kan, JS Bus, MJ Bartels
Regulatory Toxicology and Pharmacology 57 (2-3), 129-135, 2010
222010
Kinetics of monochloroacetic acid at subtoxic and toxic doses in rats after single oral and dermal administrations
SA Saghir, KK Rozman
Toxicological Sciences 76 (1), 51-64, 2003
222003
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